CR6503A - Derivados de- 1-trifluorometil-4-hidroxi-7-piperidinil-aminometiclcromano - Google Patents
Derivados de- 1-trifluorometil-4-hidroxi-7-piperidinil-aminometiclcromanoInfo
- Publication number
- CR6503A CR6503A CR6503A CR6503A CR6503A CR 6503 A CR6503 A CR 6503A CR 6503 A CR6503 A CR 6503A CR 6503 A CR6503 A CR 6503A CR 6503 A CR6503 A CR 6503A
- Authority
- CR
- Costa Rica
- Prior art keywords
- alkyl
- derivatives
- aminometiclcromano
- piperidinil
- trifluorometil
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/16—Anti-Parkinson drugs
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
Abstract
Se refiere a nuevos derivados de 1-trifluorometil-4-hidroxi-7-piperidinil-aminometilcromano de fórmula (I) en la que R1 es un alquilo C1-C6, R2 es hidrógeno, alquilo C1, C6, haloalquilo C1-C6 o fenilo, R3 es hidrógeno o halo y R4 y R5 son independientemente hidrógeno, alquilo C1-C6 o haloalquilo C1-C6, sus sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen dichos compuestos y el uso de dichos compuestos para tratar trastornos del sistema nervioso central, gastrointestinales y otros.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13539999P | 1999-05-21 | 1999-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR6503A true CR6503A (es) | 2004-02-03 |
Family
ID=22467939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR6503A CR6503A (es) | 1999-05-21 | 2001-11-19 | Derivados de- 1-trifluorometil-4-hidroxi-7-piperidinil-aminometiclcromano |
Country Status (49)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
| ATE257477T1 (de) * | 1999-10-18 | 2004-01-15 | Pfizer Prod Inc | Verfahren zur herstellung von zyklischen piperidinylaminomethyl-trifluoromethyl- etherderivaten |
| DE10311984A1 (de) * | 2003-03-12 | 2004-09-23 | Freie Universität Berlin | Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten |
| US7122700B2 (en) * | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
| US7868016B2 (en) * | 2005-07-13 | 2011-01-11 | Baxter International Inc. | Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride |
| WO2009109001A1 (en) * | 2008-03-04 | 2009-09-11 | Adelaide Research & Innovation Pty Ltd | Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function |
| WO2009158426A1 (en) | 2008-06-25 | 2009-12-30 | Array Biopharma Inc. | 6-substituted phenoxychroman carboxylic acid derivatives |
| CN117343036A (zh) * | 2023-03-20 | 2024-01-05 | 江苏联环药业股份有限公司 | 异苯并二氢吡喃类化合物及其药物组合物和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY110227A (en) * | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| GB9317987D0 (en) * | 1993-08-26 | 1993-10-13 | Glaxo Group Ltd | Chemical compounds |
| WO1996030367A1 (fr) * | 1995-03-27 | 1996-10-03 | Hisamitsu Pharmaceutical Co., Inc. | Derives de piperidine |
| RU2156250C2 (ru) * | 1995-04-24 | 2000-09-20 | Новартис Аг | Производные хромона, способ их получения и фармацевтическая композиция |
| ES2155601T3 (es) * | 1995-07-07 | 2001-05-16 | Pfizer | Compuestos de benzolactama sustituidos como antagonistas de la sustancia p. |
| TW340842B (en) * | 1995-08-24 | 1998-09-21 | Pfizer | Substituted benzylaminopiperidine compounds |
| TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
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2000
- 2000-04-20 CA CA002374643A patent/CA2374643C/en not_active Expired - Fee Related
- 2000-04-20 EE EEP200100612A patent/EE04719B1/xx not_active IP Right Cessation
- 2000-04-20 ES ES00915314T patent/ES2190781T3/es not_active Expired - Lifetime
- 2000-04-20 DE DE60001736T patent/DE60001736T2/de not_active Expired - Fee Related
- 2000-04-20 AP APAP/P/2001/002327A patent/AP1396A/en active
- 2000-04-20 EA EA200101109A patent/EA004233B1/ru not_active IP Right Cessation
- 2000-04-20 KR KR10-2001-7014803A patent/KR100453301B1/ko not_active IP Right Cessation
- 2000-04-20 CZ CZ20014164A patent/CZ20014164A3/cs unknown
- 2000-04-20 HU HU0201443A patent/HUP0201443A3/hu unknown
- 2000-04-20 SK SK1659-2001A patent/SK285819B6/sk not_active IP Right Cessation
- 2000-04-20 UA UA2001117936A patent/UA71004C2/uk unknown
- 2000-04-20 CN CNB008078750A patent/CN1140525C/zh not_active Expired - Fee Related
- 2000-04-20 MX MXPA01011977A patent/MXPA01011977A/es unknown
- 2000-04-20 DK DK00915314T patent/DK1178984T3/da active
- 2000-04-20 GE GEAP20006203A patent/GEP20043225B/en unknown
- 2000-04-20 WO PCT/IB2000/000493 patent/WO2000071538A2/en active IP Right Grant
- 2000-04-20 EP EP00915314A patent/EP1178984B1/en not_active Expired - Lifetime
- 2000-04-20 JP JP2000619795A patent/JP3802762B2/ja not_active Expired - Fee Related
- 2000-04-20 AT AT00915314T patent/ATE234832T1/de not_active IP Right Cessation
- 2000-04-20 PL PL352409A patent/PL198658B1/pl unknown
- 2000-04-20 IL IL14594900A patent/IL145949A0/xx unknown
- 2000-04-20 AU AU36673/00A patent/AU775861B2/en not_active Ceased
- 2000-04-20 TR TR2001/03332T patent/TR200103332T2/xx unknown
- 2000-04-20 BR BR0011284-4A patent/BR0011284A/pt not_active Application Discontinuation
- 2000-04-20 PT PT00915314T patent/PT1178984E/pt unknown
- 2000-04-20 NZ NZ514698A patent/NZ514698A/en unknown
- 2000-04-24 OA OA1200100302A patent/OA11944A/en unknown
- 2000-04-25 HN HN2000000057A patent/HN2000000057A/es unknown
- 2000-05-05 PA PA20008495201A patent/PA8495201A1/es unknown
- 2000-05-10 CO CO00033397A patent/CO5170464A1/es not_active Application Discontinuation
- 2000-05-16 TW TW089109370A patent/TWI275588B/zh not_active IP Right Cessation
- 2000-05-17 TN TNTNSN00105A patent/TNSN00105A1/fr unknown
- 2000-05-17 MA MA25978A patent/MA26734A1/fr unknown
- 2000-05-17 DZ DZ000087A patent/DZ3044A1/xx active
- 2000-05-17 US US09/572,213 patent/US6239147B1/en not_active Expired - Fee Related
- 2000-05-18 UY UY26147D patent/UY26147A1/es unknown
- 2000-05-18 GT GT200000073A patent/GT200000073A/es unknown
- 2000-05-19 SV SV2000000077A patent/SV2002000077A/es not_active Application Discontinuation
- 2000-05-19 PE PE2000000472A patent/PE20010165A1/es not_active Application Discontinuation
- 2000-05-19 MY MYPI20002220A patent/MY123373A/en unknown
- 2000-05-19 AR ARP000102386A patent/AR020294A1/es active IP Right Grant
- 2000-05-21 GC GCP2000665 patent/GC0000254A/en active
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2001
- 2001-10-23 IS IS6123A patent/IS6123A/is unknown
- 2001-11-19 CR CR6503A patent/CR6503A/es unknown
- 2001-11-20 HR HR20010861A patent/HRP20010861A2/hr not_active Application Discontinuation
- 2001-11-20 NO NO20015652A patent/NO322496B1/no unknown
- 2001-11-20 ZA ZA200109554A patent/ZA200109554B/en unknown
- 2001-11-26 BG BG106152A patent/BG106152A/xx unknown
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2002
- 2002-10-30 HK HK02107866.4A patent/HK1046280B/zh not_active IP Right Cessation
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