TR200103332T2 - 1-Triflorometil-4-hidroksi-7-piperidinil-aminometilkroman türevleri. - Google Patents

1-Triflorometil-4-hidroksi-7-piperidinil-aminometilkroman türevleri.

Info

Publication number
TR200103332T2
TR200103332T2 TR2001/03332T TR200103332T TR200103332T2 TR 200103332 T2 TR200103332 T2 TR 200103332T2 TR 2001/03332 T TR2001/03332 T TR 2001/03332T TR 200103332 T TR200103332 T TR 200103332T TR 200103332 T2 TR200103332 T2 TR 200103332T2
Authority
TR
Turkey
Prior art keywords
alkyl
piperidinyl
trifluoromethyl
hydroxy
halo
Prior art date
Application number
TR2001/03332T
Other languages
English (en)
Inventor
Scott Obach Ronald
Alan Scully Douglas
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200103332T2 publication Critical patent/TR200103332T2/tr

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

Bu bulus, R1'in C1-C6 alkil; R2'nin hidrojen, C1-C6 alkil, halo C1-C6 alkil veya fenil; R3'ün hidrojen veya halo; R4 ve R5'in bagimsiz bir sekilde hidrojen, C1-C6 alkil veya halo C1-C6 alkil oldugu formül (I)'e ait yeni 1-triflorometil-4-hidroksi-7-piperidinil-aminometil-kroman türevleriyle, bunlarin farmasötik açidan kabul gören tuzlariyla, bu bileskleri ihtiva eden farmasötik kompozisyonlarla ve bu bilesiklerin, CNS, mide-barsak ve diger bozukluklarin tedavisinde kullanilmasiyla ilgilidir. (Formül var)
TR2001/03332T 1999-05-21 2000-04-20 1-Triflorometil-4-hidroksi-7-piperidinil-aminometilkroman türevleri. TR200103332T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13539999P 1999-05-21 1999-05-21

Publications (1)

Publication Number Publication Date
TR200103332T2 true TR200103332T2 (tr) 2002-04-22

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ID=22467939

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TR2001/03332T TR200103332T2 (tr) 1999-05-21 2000-04-20 1-Triflorometil-4-hidroksi-7-piperidinil-aminometilkroman türevleri.

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US (1) US6239147B1 (tr)
EP (1) EP1178984B1 (tr)
JP (1) JP3802762B2 (tr)
KR (1) KR100453301B1 (tr)
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Families Citing this family (7)

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TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
ES2211455T3 (es) * 1999-10-18 2004-07-16 Pfizer Products Inc. Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometil trifluorometilicos.
DE10311984A1 (de) * 2003-03-12 2004-09-23 Freie Universität Berlin Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten
US7122700B2 (en) * 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
US7868016B2 (en) * 2005-07-13 2011-01-11 Baxter International Inc. Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
WO2009109001A1 (en) * 2008-03-04 2009-09-11 Adelaide Research & Innovation Pty Ltd Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function
EP3144303B1 (en) 2008-06-25 2018-09-26 Array Biopharma, Inc. 6-substituted phenoxychroman carboxylic acid derivatives

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MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
EP0826684B1 (en) * 1995-03-27 2001-11-21 Hisamitsu Pharmaceutical Co., Inc. Piperidine derivatives
RU2156250C2 (ru) * 1995-04-24 2000-09-20 Новартис Аг Производные хромона, способ их получения и фармацевтическая композиция
ATE199552T1 (de) * 1995-07-07 2001-03-15 Pfizer Substituierte benzolaktamverbindungen als substanz-p-antagonisten
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

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ES2190781T3 (es) 2003-08-16
SV2002000077A (es) 2002-07-03
KR100453301B1 (ko) 2004-10-20
GC0000254A (en) 2006-11-01
WO2000071538A3 (en) 2001-02-22
BG106152A (en) 2002-06-28
AP2001002327A0 (en) 2001-12-31
DK1178984T3 (da) 2003-06-10
HN2000000057A (es) 2001-03-02
NO322496B1 (no) 2006-10-16
CN1355799A (zh) 2002-06-26
AR020294A1 (es) 2002-05-02
NO20015652D0 (no) 2001-11-20
WO2000071538A2 (en) 2000-11-30
SK16592001A3 (sk) 2003-03-04
MXPA01011977A (es) 2002-05-06
AU3667300A (en) 2000-12-12
NZ514698A (en) 2005-01-28
CR6503A (es) 2004-02-03
BR0011284A (pt) 2002-03-05
CZ20014164A3 (cs) 2003-01-15
SK285819B6 (sk) 2007-09-06
UY26147A1 (es) 2000-12-29
NO20015652L (no) 2002-01-14

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