AR020294A1 - COMPUESTOS DERIVADOS DE 1-TRIFLUOROMETIL-4-HIDROXI-7-PIPERIDINIL-AMINOMETILCROMANO, COMPOSICION FARMACEUTICA Y USO EN LA PREPARACIoN DE MEDICAMENTOS. - Google Patents

COMPUESTOS DERIVADOS DE 1-TRIFLUOROMETIL-4-HIDROXI-7-PIPERIDINIL-AMINOMETILCROMANO, COMPOSICION FARMACEUTICA Y USO EN LA PREPARACIoN DE MEDICAMENTOS.

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Publication number
AR020294A1
AR020294A1 ARP000102386A ARP000102386A AR020294A1 AR 020294 A1 AR020294 A1 AR 020294A1 AR P000102386 A ARP000102386 A AR P000102386A AR P000102386 A ARP000102386 A AR P000102386A AR 020294 A1 AR020294 A1 AR 020294A1
Authority
AR
Argentina
Prior art keywords
aminometilcromano
piperidinil
trifluorometil
hidroxi
medicines
Prior art date
Application number
ARP000102386A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020294A1 publication Critical patent/AR020294A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Esta se refiere a nuevos derivados de 1-trifluorometil-4-hidroxi-7-piperidinil-aminometilcromano de formula (I), en la que R1 es alquilo C1-6; R2 eshidrogeno, alquilo C1-6, haloalquilo C1-6 o fenilo; R3 es hidrogeno o halo; y R4 y R5 sonindependient emente hidrogeno, alquilo C1-6 o haloalquilo C1-6; sussales farmacéuticamente aceptables, composiciones farmacéuticas que contienen dichos compuestos y el uso de dichos compuestos para tratar trastornos delsistema nervioso central,gastrointestinales y otros.
ARP000102386A 1999-05-21 2000-05-19 COMPUESTOS DERIVADOS DE 1-TRIFLUOROMETIL-4-HIDROXI-7-PIPERIDINIL-AMINOMETILCROMANO, COMPOSICION FARMACEUTICA Y USO EN LA PREPARACIoN DE MEDICAMENTOS. AR020294A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13539999P 1999-05-21 1999-05-21

Publications (1)

Publication Number Publication Date
AR020294A1 true AR020294A1 (es) 2002-05-02

Family

ID=22467939

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102386A AR020294A1 (es) 1999-05-21 2000-05-19 COMPUESTOS DERIVADOS DE 1-TRIFLUOROMETIL-4-HIDROXI-7-PIPERIDINIL-AMINOMETILCROMANO, COMPOSICION FARMACEUTICA Y USO EN LA PREPARACIoN DE MEDICAMENTOS.

Country Status (49)

Country Link
US (1) US6239147B1 (es)
EP (1) EP1178984B1 (es)
JP (1) JP3802762B2 (es)
KR (1) KR100453301B1 (es)
CN (1) CN1140525C (es)
AP (1) AP1396A (es)
AR (1) AR020294A1 (es)
AT (1) ATE234832T1 (es)
AU (1) AU775861B2 (es)
BG (1) BG106152A (es)
BR (1) BR0011284A (es)
CA (1) CA2374643C (es)
CO (1) CO5170464A1 (es)
CR (1) CR6503A (es)
CZ (1) CZ20014164A3 (es)
DE (1) DE60001736T2 (es)
DK (1) DK1178984T3 (es)
DZ (1) DZ3044A1 (es)
EA (1) EA004233B1 (es)
EE (1) EE04719B1 (es)
ES (1) ES2190781T3 (es)
GC (1) GC0000254A (es)
GE (1) GEP20043225B (es)
GT (1) GT200000073A (es)
HK (1) HK1046280B (es)
HN (1) HN2000000057A (es)
HR (1) HRP20010861A2 (es)
HU (1) HUP0201443A3 (es)
IL (1) IL145949A0 (es)
IS (1) IS6123A (es)
MA (1) MA26734A1 (es)
MX (1) MXPA01011977A (es)
MY (1) MY123373A (es)
NO (1) NO322496B1 (es)
NZ (1) NZ514698A (es)
OA (1) OA11944A (es)
PA (1) PA8495201A1 (es)
PE (1) PE20010165A1 (es)
PL (1) PL198658B1 (es)
PT (1) PT1178984E (es)
SK (1) SK285819B6 (es)
SV (1) SV2002000077A (es)
TN (1) TNSN00105A1 (es)
TR (1) TR200103332T2 (es)
TW (1) TWI275588B (es)
UA (1) UA71004C2 (es)
UY (1) UY26147A1 (es)
WO (1) WO2000071538A2 (es)
ZA (1) ZA200109554B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
ES2211455T3 (es) * 1999-10-18 2004-07-16 Pfizer Products Inc. Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometil trifluorometilicos.
DE10311984A1 (de) * 2003-03-12 2004-09-23 Freie Universität Berlin Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten
US7122700B2 (en) * 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
US7868016B2 (en) * 2005-07-13 2011-01-11 Baxter International Inc. Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
WO2009109001A1 (en) * 2008-03-04 2009-09-11 Adelaide Research & Innovation Pty Ltd Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function
NZ590437A (en) 2008-06-25 2012-07-27 Array Biopharma Inc 6-substituted phenoxychroman carboxylic acid derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
AU696948B2 (en) * 1995-03-27 1998-09-24 Hisamitsu Pharmaceutical Co., Inc. Piperidine derivatives
TW475930B (en) * 1995-04-24 2002-02-11 Novartis Ag Novel compound, its use and pharmaceutical composition comprising it
JP3042894B2 (ja) * 1995-07-07 2000-05-22 ファイザー製薬株式会社 サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

Also Published As

Publication number Publication date
CN1355799A (zh) 2002-06-26
NO322496B1 (no) 2006-10-16
CR6503A (es) 2004-02-03
PT1178984E (pt) 2003-06-30
NO20015652L (no) 2002-01-14
ES2190781T3 (es) 2003-08-16
GT200000073A (es) 2001-11-09
EA004233B1 (ru) 2004-02-26
NZ514698A (en) 2005-01-28
CZ20014164A3 (cs) 2003-01-15
EP1178984A2 (en) 2002-02-13
IS6123A (is) 2001-10-23
MY123373A (en) 2006-05-31
DK1178984T3 (da) 2003-06-10
AU775861B2 (en) 2004-08-19
DE60001736D1 (de) 2003-04-24
GC0000254A (en) 2006-11-01
MXPA01011977A (es) 2002-05-06
SK285819B6 (sk) 2007-09-06
KR100453301B1 (ko) 2004-10-20
TNSN00105A1 (fr) 2005-11-10
PA8495201A1 (es) 2002-08-26
TR200103332T2 (tr) 2002-04-22
HK1046280A1 (en) 2003-01-03
MA26734A1 (fr) 2004-12-20
PL198658B1 (pl) 2008-07-31
PL352409A1 (en) 2003-08-25
WO2000071538A2 (en) 2000-11-30
EE200100612A (et) 2003-02-17
CA2374643A1 (en) 2000-11-30
OA11944A (en) 2006-04-12
JP2003500405A (ja) 2003-01-07
SK16592001A3 (sk) 2003-03-04
EA200101109A1 (ru) 2002-04-25
BG106152A (en) 2002-06-28
CO5170464A1 (es) 2002-06-27
US6239147B1 (en) 2001-05-29
DE60001736T2 (de) 2003-09-18
AP2001002327A0 (en) 2001-12-31
GEP20043225B (en) 2004-04-26
AU3667300A (en) 2000-12-12
WO2000071538A3 (en) 2001-02-22
HUP0201443A2 (en) 2002-08-28
BR0011284A (pt) 2002-03-05
HRP20010861A2 (en) 2003-04-30
HUP0201443A3 (en) 2005-09-28
UY26147A1 (es) 2000-12-29
SV2002000077A (es) 2002-07-03
HK1046280B (zh) 2004-10-21
JP3802762B2 (ja) 2006-07-26
IL145949A0 (en) 2002-07-25
CA2374643C (en) 2006-02-14
ATE234832T1 (de) 2003-04-15
CN1140525C (zh) 2004-03-03
UA71004C2 (uk) 2004-11-15
EP1178984B1 (en) 2003-03-19
DZ3044A1 (fr) 2004-03-27
AP1396A (en) 2005-04-19
PE20010165A1 (es) 2001-02-20
ZA200109554B (en) 2002-11-20
EE04719B1 (et) 2006-10-16
TWI275588B (en) 2007-03-11
HN2000000057A (es) 2001-03-02
KR20020016793A (ko) 2002-03-06
NO20015652D0 (no) 2001-11-20

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