DE50107641D1 - Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität - Google Patents
Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilitätInfo
- Publication number
- DE50107641D1 DE50107641D1 DE50107641T DE50107641T DE50107641D1 DE 50107641 D1 DE50107641 D1 DE 50107641D1 DE 50107641 T DE50107641 T DE 50107641T DE 50107641 T DE50107641 T DE 50107641T DE 50107641 D1 DE50107641 D1 DE 50107641D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- coating
- binding agent
- storage stability
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011230 binding agent Substances 0.000 title abstract 4
- 239000011248 coating agent Substances 0.000 title abstract 4
- 238000000576 coating method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 238000005266 casting Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 238000003892 spreading Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2001/002018 WO2002067906A1 (de) | 2001-02-27 | 2001-02-27 | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE50107641D1 true DE50107641D1 (de) | 2005-11-10 |
Family
ID=8164308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50107641T Expired - Lifetime DE50107641D1 (de) | 2001-02-27 | 2001-02-27 | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität |
Country Status (19)
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7303763B2 (en) * | 2001-02-12 | 2007-12-04 | Watson Laboratories, Inc. | Compositions for conjugated estrogens and associated methods |
| DE10149674A1 (de) * | 2001-10-09 | 2003-04-24 | Apogepha Arzneimittel Gmbh | Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung |
| US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
| TWI312285B (en) * | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| DE10239999A1 (de) * | 2002-08-27 | 2004-03-04 | Röhm GmbH & Co. KG | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
| DE10260921A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
| DE10260920A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen |
| DE10260919A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug |
| DE10304403A1 (de) * | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| DE60301277T2 (de) * | 2003-12-09 | 2006-03-30 | Helm Ag | Pharmazeutische zubereitung enthaltend valaciclovir |
| JP4607478B2 (ja) * | 2004-03-17 | 2011-01-05 | 株式会社トクホン | 貼付剤用両面離型フィルム |
| JP4895819B2 (ja) * | 2004-10-29 | 2012-03-14 | 大鵬薬品工業株式会社 | プロピベリン含有経口粉粒状製剤及びその製造法 |
| DE102005042039A1 (de) * | 2005-09-02 | 2007-03-08 | Basf Ag | Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität |
| ITFI20050206A1 (it) * | 2005-09-30 | 2007-04-01 | Valpharma Sa | Composizione farmaceutica a rilascio controllato di venlafaxina cloridrato, e processo per la sua preparazione |
| US20090176882A1 (en) * | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| EP2176301B1 (de) | 2007-08-02 | 2013-05-15 | Basf Se | Wässrige polymerdispersion auf basis von n, n-diethylaminoethylmethacrylat, deren herstellung und verwendung |
| WO2010030735A2 (en) * | 2008-09-11 | 2010-03-18 | Aethos Pharmaceuticals, Inc. | Stabilized coating for pharmaceutical formulations |
| DE102008058556A1 (de) * | 2008-11-21 | 2010-05-27 | Pröstler, Karl-Heinz, Dipl.-Ing. | Verfahren zur Trockenbeschichtung |
| KR101647869B1 (ko) * | 2009-07-30 | 2016-08-11 | 에보니크 룀 게엠베하 | 공중합체, 디카르복실산 및 지방 모노카르복실산을 포함하는 분말 또는 과립 조성물 |
| CN105419206B (zh) * | 2009-07-30 | 2017-12-15 | 赢创罗姆有限公司 | 包含共聚物、二羧酸和脂肪单羧酸的粉末状或粒状组合物 |
| CA2769252C (en) | 2009-07-30 | 2016-01-12 | Evonik Roehm Gmbh | Powdery or granulated composition comprising a copolymer, a salt of a fatty monocarboxylic acid and a fatty monocarboxylic acid and/or a fatty alcohol |
| WO2011051155A2 (en) | 2009-10-28 | 2011-05-05 | Basf Se | Stable protective coatings for pharmaceutical dosage forms |
| CN102665763B (zh) * | 2009-11-30 | 2013-10-23 | 东丽株式会社 | 固体制剂用的薄膜包衣剂和使用该包衣剂的固体制剂 |
| TWI480067B (zh) | 2010-02-26 | 2015-04-11 | Toray Industries | 經包衣之固體製劑 |
| EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
| CA2803052C (en) | 2010-08-31 | 2014-10-28 | Toray Industries, Inc. | Coating agent for pharmaceutical solid preparation, pharmaceutical film formulation, and coated pharmaceutical solid preparation |
| CN103189052A (zh) | 2010-09-07 | 2013-07-03 | 巴斯夫欧洲公司 | 基于含氨基聚合物的共聚物作为基质粘合剂在制备含活性成分的颗粒和给药形式中的用途 |
| EP2621479B1 (de) | 2010-09-27 | 2017-11-29 | Basf Se | Protektive überzüge für saure wirkstoffe |
| US9795576B2 (en) | 2010-09-27 | 2017-10-24 | Basf Se | Protective coatings for acidic active ingredients |
| US8865250B2 (en) | 2011-02-28 | 2014-10-21 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US8962064B2 (en) | 2011-02-28 | 2015-02-24 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| BR112013021510B1 (pt) | 2011-02-28 | 2020-09-24 | Basf Se | Processo para a produção de composições de revestimento em pó, e, uso de um pó de polímero |
| EP2681263B1 (de) | 2011-02-28 | 2018-09-12 | Basf Se | Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen |
| US9044734B2 (en) | 2011-09-23 | 2015-06-02 | Basf Se | Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion |
| US20130236505A1 (en) | 2012-03-09 | 2013-09-12 | Basf Se | Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment |
| EP2636403A1 (de) | 2012-03-09 | 2013-09-11 | Basf Se | Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu |
| EP2863953A1 (de) | 2012-06-22 | 2015-04-29 | Basf Se | Wirkstoffhaltige festen dispersionen auf basis von diethylaminoethylmethacrylat-copolymeren |
| US10668156B2 (en) | 2012-06-22 | 2020-06-02 | Basf Se | Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers |
| CA2886626A1 (en) * | 2012-09-28 | 2014-04-03 | Evonik Industries Ag | Process for preparing aqueous dispersions |
| EP2922907A1 (en) | 2012-11-22 | 2015-09-30 | Evonik Röhm GmbH | Process for preparing a granulated product from a powder composition |
| EP2801349A1 (en) | 2013-05-06 | 2014-11-12 | Siegfried AG | Oral Pharmaceutical Formulation |
| US20200315978A1 (en) * | 2015-07-17 | 2020-10-08 | BE Pharbel Manufacturing | Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form |
| US11046668B2 (en) | 2016-03-11 | 2021-06-29 | Ohio State Innovation Foundation | Small molecule antimicrobials |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| US12031128B2 (en) | 2021-04-07 | 2024-07-09 | Battelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957966A (en) * | 1972-05-19 | 1976-05-18 | Gaf Corporation | Stabilized vitamin food coatings |
| JPS49107855A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-02-03 | 1974-10-14 | ||
| JPS5191317A (ja) * | 1975-02-04 | 1976-08-10 | Boshitsuseihifukuyakuzainoseizohoho | |
| JPS51112564A (en) * | 1975-03-28 | 1976-10-05 | Ajinomoto Kk | Production of nutritive matearial for diet food |
| JPS52117413A (en) * | 1976-03-26 | 1977-10-01 | Sankyo Co Ltd | Protective coating composition using aqueous solvent |
| US4341563A (en) * | 1978-11-17 | 1982-07-27 | Sankyo Company Limited | Protective coating compositions |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS6032714A (ja) * | 1983-08-01 | 1985-02-19 | Teijin Ltd | 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物 |
| CH668553A5 (de) * | 1987-02-02 | 1989-01-13 | Mepha Ag | Arzneimittel mit verzoegerter wirkstofffreisetzung. |
| DE4026992A1 (de) | 1990-08-25 | 1992-02-27 | Roehm Gmbh | Verfahren zur herstellung von traegersystemen fuer biologisch aktive materialien |
| JP2973751B2 (ja) * | 1991-12-04 | 1999-11-08 | 大正製薬株式会社 | 矯味経口組成物の製造方法 |
| ES2174849T3 (es) * | 1992-06-04 | 2002-11-16 | Smithkline Beecham Corp | Composiciones farmaceuticas con sabor agradable. |
| DE4310012A1 (de) | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
| DE19653606A1 (de) | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
| DE19715794C1 (de) | 1997-04-16 | 1998-12-03 | Roehm Gmbh | Laminare Arzneiform und Verfahren zu ihrer Herstellung |
| EP1426420A3 (en) | 1997-08-15 | 2005-12-14 | Eastman Chemical Company | The use of surfactants as plasticizers to reduce volatile organic compounds in water-based polymer coating compositions |
| DE19918435A1 (de) | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Überzugs- und Bindemittel für orale oder dermale Arzneiformen |
| AU6228799A (en) | 1998-10-26 | 2000-05-15 | Tanabe Seiyaku Co., Ltd. | Sustained-release particles |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| KR100695043B1 (ko) * | 2000-02-25 | 2007-03-14 | 닛뽕 뻬인또 가부시키가이샤 | 도료 조성물 |
-
2001
- 2001-02-27 SK SK1371-2002A patent/SK288049B6/sk not_active IP Right Cessation
- 2001-02-27 PL PL356961A patent/PL200270B1/pl unknown
- 2001-02-27 DE DE50107641T patent/DE50107641D1/de not_active Expired - Lifetime
- 2001-02-27 ES ES01913827T patent/ES2248291T3/es not_active Expired - Lifetime
- 2001-02-27 IL IL15115101A patent/IL151151A0/xx active IP Right Grant
- 2001-02-27 CN CNB018071902A patent/CN1192767C/zh not_active Expired - Lifetime
- 2001-02-27 JP JP2002567274A patent/JP4938204B2/ja not_active Expired - Lifetime
- 2001-02-27 BR BRPI0110321-0 patent/BRPI0110321B8/pt not_active IP Right Cessation
- 2001-02-27 EP EP01913827A patent/EP1368007B1/de not_active Expired - Lifetime
- 2001-02-27 KR KR20027014413A patent/KR100510356B1/ko not_active Expired - Lifetime
- 2001-02-27 HK HK03106496.3A patent/HK1054195B/zh not_active IP Right Cessation
- 2001-02-27 US US10/239,634 patent/US7160558B2/en not_active Expired - Lifetime
- 2001-02-27 HU HU0300388A patent/HU229344B1/hu not_active IP Right Cessation
- 2001-02-27 AT AT01913827T patent/ATE305774T1/de active
- 2001-02-27 MX MXPA02010382 patent/MX229421B/es active IP Right Grant
- 2001-02-27 WO PCT/EP2001/002018 patent/WO2002067906A1/de active IP Right Grant
- 2001-02-27 CA CA002403831A patent/CA2403831C/en not_active Expired - Lifetime
-
2002
- 2002-08-08 IL IL151151A patent/IL151151A/en unknown
- 2002-09-26 BG BG107148A patent/BG65879B1/bg unknown
- 2002-10-21 IN IN1723CH2002 patent/IN2002CH01723A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE305774T1 (de) | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität | |
| TR200100196T2 (tr) | Oral veya dermal ilaç biçimleri için kaplama ve birleştirme maddeleri | |
| MXPA04003970A (es) | Granulos o polvo para la produccion de agentes de recubrimiento y aglutinantes para formas farmaceuticas. | |
| EP0704208A3 (de) | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform | |
| EP2158905A3 (en) | Composition for the Transdermal Delivery of Fentanyl | |
| ATE536173T1 (de) | Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol | |
| MXPA01003392A (es) | Formas de medicamento recubiertas con una liberacion controlada de sustancia activa. | |
| NZ505431A (en) | Solid thermoformable controlled-release pharmaceutical composition | |
| ATE553754T1 (de) | Pharmazeutische zusammensetzung mit kontrollierter wirkstoffabgabe für wirkstoffe mit guter löslichkeit in wasser | |
| DE59907676D1 (de) | Wässrige Dispersion geeignet zur Herstellung von Überzugs- und Bindemitteln für feste orale Arzneiformen | |
| WO2001085257A3 (en) | Opioid antagonist compositions and dosage forms | |
| UA93530C2 (ru) | Композиция c пролонгированным высвобождением активного вещества, способ ee получения и применения | |
| IE831433L (en) | Cementiferous compositions comprising a copolymer as a¹plasticiser additive | |
| TW345590B (en) | Coating composition for concrete structures | |
| MXPA04003540A (es) | Utilizacion de un copolimero para producir una forma galenica que contiene un peptido o proteina como agente activo. | |
| WO2002060417A8 (de) | Lagerstabiles haft- und bindemittel für pharmazeutische anwendungen | |
| DE60201117D1 (de) | Mikrogranulate von Ursodeoxycholsäure | |
| RU2002107929A (ru) | Противовирусный лекарственный препарат для перорального применения | |
| BG108668A (en) | Use of a copolymer to produce a galenic form containing a peptide or a protein as active agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ROEHM GMBH, 64293 DARMSTADT, DE |
|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: EVONIK ROEHM GMBH, 64293 DARMSTADT, DE |