DE3878806T2 - Leukotrien ltd4 und ltb4-antagonisten. - Google Patents

Leukotrien ltd4 und ltb4-antagonisten.

Info

Publication number
DE3878806T2
DE3878806T2 DE8888115671T DE3878806T DE3878806T2 DE 3878806 T2 DE3878806 T2 DE 3878806T2 DE 8888115671 T DE8888115671 T DE 8888115671T DE 3878806 T DE3878806 T DE 3878806T DE 3878806 T2 DE3878806 T2 DE 3878806T2
Authority
DE
Germany
Prior art keywords
methyl
thio
propylphenoxy
acetyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888115671T
Other languages
German (de)
English (en)
Other versions
DE3878806D1 (de
Inventor
James Ronald Deason
Michael Allan Stealey
Richard Mathias Weier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE3878806D1 publication Critical patent/DE3878806D1/de
Publication of DE3878806T2 publication Critical patent/DE3878806T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DE8888115671T 1987-09-24 1988-09-23 Leukotrien ltd4 und ltb4-antagonisten. Expired - Fee Related DE3878806T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (2)

Publication Number Publication Date
DE3878806D1 DE3878806D1 (de) 1993-04-08
DE3878806T2 true DE3878806T2 (de) 1993-07-01

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888115671T Expired - Fee Related DE3878806T2 (de) 1987-09-24 1988-09-23 Leukotrien ltd4 und ltb4-antagonisten.

Country Status (14)

Country Link
US (1) US4923891A (enExample)
EP (1) EP0308956B1 (enExample)
JP (1) JPH01132577A (enExample)
KR (1) KR890005082A (enExample)
AU (1) AU610246B2 (enExample)
DE (1) DE3878806T2 (enExample)
DK (1) DK530888A (enExample)
ES (1) ES2045052T3 (enExample)
FI (1) FI884377L (enExample)
GR (1) GR3007858T3 (enExample)
IL (1) IL87800A (enExample)
NO (1) NO171412C (enExample)
NZ (1) NZ226318A (enExample)
PT (1) PT88580B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
US6342510B1 (en) 1995-06-12 2002-01-29 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
ES2243978T3 (es) * 1996-02-13 2005-12-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4.
EP1090916B1 (en) * 1999-10-06 2003-09-03 Dainippon Ink And Chemicals, Inc. 4-methylene-1,3-dioxolanes having functional groups
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
KR101390488B1 (ko) 2005-11-22 2014-05-26 세게티스, 인코포레이티드. 글리세롤 레불리네이트 케탈 및 그의 용도
CA2668294C (en) * 2007-10-09 2010-12-07 Segetis, Inc. Method of making ketals and acetals
US8575367B2 (en) 2008-09-25 2013-11-05 Segetis, Inc. Ketal ester derivatives
WO2010151558A1 (en) 2009-06-22 2010-12-29 Segetis, Inc. Ketal compounds and uses thereof
KR20130070608A (ko) 2010-05-10 2013-06-27 세게티스, 인코포레이티드. 미립자 고체에 대한 분산제 및 슬립제로서의 알킬 케탈 에스터 및 그의 제조방법, 및 용도
CA2806352C (en) 2010-08-03 2019-09-24 Segetis, Inc. Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
CN103052691B (zh) 2010-08-12 2014-05-28 赛格提斯有限公司 包含羧基酯缩酮聚结物的胶乳涂层组合物、其制备方法和应用
CN103069343B (zh) 2010-08-12 2015-09-09 赛格提斯有限公司 羧基酯缩酮除去组合物、其制造方法及应用
EP2613760A2 (en) 2010-09-07 2013-07-17 Segetis, Inc. Compositions for dyeing keratin fibers
CN103097604A (zh) 2010-09-13 2013-05-08 赛格提斯有限公司 织物软化剂组合物及其制造方法
EP2630205A4 (en) 2010-10-18 2015-01-21 Segetis Inc WATER-REDUCING COATING COMPOSITIONS COMPRISING CARBOXY ETHER KETALS, METHODS OF MAKING THE SAME, AND USES THEREOF
WO2014047428A1 (en) 2012-09-21 2014-03-27 Segetis, Inc. Cleaning, surfactant, and personal care compositions
CN104918929A (zh) 2012-11-29 2015-09-16 赛格提斯公司 羧基酯缩酮、其制造方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR4493M (enExample) * 1964-07-09 1966-10-10
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
US4923891A (en) 1990-05-08
GR3007858T3 (enExample) 1993-08-31
DK530888D0 (da) 1988-09-23
EP0308956A2 (en) 1989-03-29
PT88580B (pt) 1992-11-30
DK530888A (da) 1989-03-25
AU610246B2 (en) 1991-05-16
EP0308956B1 (en) 1993-03-03
AU2274188A (en) 1989-04-06
NO171412C (no) 1993-03-10
EP0308956A3 (en) 1990-06-13
FI884377A7 (fi) 1989-03-25
IL87800A (en) 1992-12-01
NZ226318A (en) 1991-08-27
NO884223L (no) 1989-03-28
FI884377L (fi) 1989-03-25
KR890005082A (ko) 1989-05-11
NO171412B (no) 1992-11-30
DE3878806D1 (de) 1993-04-08
ES2045052T3 (es) 1994-01-16
FI884377A0 (fi) 1988-09-23
PT88580A (pt) 1988-10-01
NO884223D0 (no) 1988-09-23
JPH01132577A (ja) 1989-05-25
IL87800A0 (en) 1989-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee