PT88580B - Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 - Google Patents

Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 Download PDF

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Publication number
PT88580B
PT88580B PT88580A PT8858088A PT88580B PT 88580 B PT88580 B PT 88580B PT 88580 A PT88580 A PT 88580A PT 8858088 A PT8858088 A PT 8858088A PT 88580 B PT88580 B PT 88580B
Authority
PT
Portugal
Prior art keywords
hydroxy
isomers
propylphenoxy
process according
prepared
Prior art date
Application number
PT88580A
Other languages
English (en)
Portuguese (pt)
Other versions
PT88580A (pt
Inventor
Richard Mathias Weier
Michael Allan Stealey
James Ronald Deason
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT88580A publication Critical patent/PT88580A/pt
Publication of PT88580B publication Critical patent/PT88580B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT88580A 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 PT88580B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (2)

Publication Number Publication Date
PT88580A PT88580A (pt) 1988-10-01
PT88580B true PT88580B (pt) 1992-11-30

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88580A PT88580B (pt) 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4

Country Status (14)

Country Link
US (1) US4923891A (enExample)
EP (1) EP0308956B1 (enExample)
JP (1) JPH01132577A (enExample)
KR (1) KR890005082A (enExample)
AU (1) AU610246B2 (enExample)
DE (1) DE3878806T2 (enExample)
DK (1) DK530888A (enExample)
ES (1) ES2045052T3 (enExample)
FI (1) FI884377L (enExample)
GR (1) GR3007858T3 (enExample)
IL (1) IL87800A (enExample)
NO (1) NO171412C (enExample)
NZ (1) NZ226318A (enExample)
PT (1) PT88580B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
US6342510B1 (en) 1995-06-12 2002-01-29 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
ES2243978T3 (es) * 1996-02-13 2005-12-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4.
EP1090916B1 (en) * 1999-10-06 2003-09-03 Dainippon Ink And Chemicals, Inc. 4-methylene-1,3-dioxolanes having functional groups
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
KR101390488B1 (ko) 2005-11-22 2014-05-26 세게티스, 인코포레이티드. 글리세롤 레불리네이트 케탈 및 그의 용도
CA2668294C (en) * 2007-10-09 2010-12-07 Segetis, Inc. Method of making ketals and acetals
US8575367B2 (en) 2008-09-25 2013-11-05 Segetis, Inc. Ketal ester derivatives
WO2010151558A1 (en) 2009-06-22 2010-12-29 Segetis, Inc. Ketal compounds and uses thereof
KR20130070608A (ko) 2010-05-10 2013-06-27 세게티스, 인코포레이티드. 미립자 고체에 대한 분산제 및 슬립제로서의 알킬 케탈 에스터 및 그의 제조방법, 및 용도
CA2806352C (en) 2010-08-03 2019-09-24 Segetis, Inc. Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
CN103052691B (zh) 2010-08-12 2014-05-28 赛格提斯有限公司 包含羧基酯缩酮聚结物的胶乳涂层组合物、其制备方法和应用
CN103069343B (zh) 2010-08-12 2015-09-09 赛格提斯有限公司 羧基酯缩酮除去组合物、其制造方法及应用
EP2613760A2 (en) 2010-09-07 2013-07-17 Segetis, Inc. Compositions for dyeing keratin fibers
CN103097604A (zh) 2010-09-13 2013-05-08 赛格提斯有限公司 织物软化剂组合物及其制造方法
EP2630205A4 (en) 2010-10-18 2015-01-21 Segetis Inc WATER-REDUCING COATING COMPOSITIONS COMPRISING CARBOXY ETHER KETALS, METHODS OF MAKING THE SAME, AND USES THEREOF
WO2014047428A1 (en) 2012-09-21 2014-03-27 Segetis, Inc. Cleaning, surfactant, and personal care compositions
CN104918929A (zh) 2012-11-29 2015-09-16 赛格提斯公司 羧基酯缩酮、其制造方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR4493M (enExample) * 1964-07-09 1966-10-10
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
US4923891A (en) 1990-05-08
GR3007858T3 (enExample) 1993-08-31
DK530888D0 (da) 1988-09-23
EP0308956A2 (en) 1989-03-29
DK530888A (da) 1989-03-25
AU610246B2 (en) 1991-05-16
EP0308956B1 (en) 1993-03-03
AU2274188A (en) 1989-04-06
NO171412C (no) 1993-03-10
DE3878806T2 (de) 1993-07-01
EP0308956A3 (en) 1990-06-13
FI884377A7 (fi) 1989-03-25
IL87800A (en) 1992-12-01
NZ226318A (en) 1991-08-27
NO884223L (no) 1989-03-28
FI884377L (fi) 1989-03-25
KR890005082A (ko) 1989-05-11
NO171412B (no) 1992-11-30
DE3878806D1 (de) 1993-04-08
ES2045052T3 (es) 1994-01-16
FI884377A0 (fi) 1988-09-23
PT88580A (pt) 1988-10-01
NO884223D0 (no) 1988-09-23
JPH01132577A (ja) 1989-05-25
IL87800A0 (en) 1989-03-31

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Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920521

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941130