JPH01132577A - ロイコトリエンltd↓4およびltb↓4アンタゴニスト - Google Patents

ロイコトリエンltd↓4およびltb↓4アンタゴニスト

Info

Publication number
JPH01132577A
JPH01132577A JP63239589A JP23958988A JPH01132577A JP H01132577 A JPH01132577 A JP H01132577A JP 63239589 A JP63239589 A JP 63239589A JP 23958988 A JP23958988 A JP 23958988A JP H01132577 A JPH01132577 A JP H01132577A
Authority
JP
Japan
Prior art keywords
methyl
compound
thio
propylphenoxy
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63239589A
Other languages
English (en)
Japanese (ja)
Inventor
James R Deason
ジェームス ロナルド ディーソン
Michael A Stealey
マイクル アラン スティーリィ
Richard M Weier
リチャード マシアス ウェイアー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of JPH01132577A publication Critical patent/JPH01132577A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP63239589A 1987-09-24 1988-09-24 ロイコトリエンltd↓4およびltb↓4アンタゴニスト Pending JPH01132577A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US100685 1987-09-24
US241265 1988-09-09
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (1)

Publication Number Publication Date
JPH01132577A true JPH01132577A (ja) 1989-05-25

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63239589A Pending JPH01132577A (ja) 1987-09-24 1988-09-24 ロイコトリエンltd↓4およびltb↓4アンタゴニスト

Country Status (14)

Country Link
US (1) US4923891A (enExample)
EP (1) EP0308956B1 (enExample)
JP (1) JPH01132577A (enExample)
KR (1) KR890005082A (enExample)
AU (1) AU610246B2 (enExample)
DE (1) DE3878806T2 (enExample)
DK (1) DK530888A (enExample)
ES (1) ES2045052T3 (enExample)
FI (1) FI884377A7 (enExample)
GR (1) GR3007858T3 (enExample)
IL (1) IL87800A (enExample)
NO (1) NO171412C (enExample)
NZ (1) NZ226318A (enExample)
PT (1) PT88580B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001158781A (ja) * 1999-10-06 2001-06-12 Dainippon Ink & Chem Inc 官能基を有する4−メチレン−1,3−ジオキソランおよびその製造方法

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
EP0833664A1 (en) 1995-06-12 1998-04-08 G.D. SEARLE & CO. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b 4? receptor antagonist for the treatment of inflammations
ES2243978T3 (es) * 1996-02-13 2005-12-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4.
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
CN103396393B (zh) * 2005-11-22 2016-03-02 塞格提斯有限公司 甘油乙酰丙酸酯缩酮及其用途
CA2668294C (en) * 2007-10-09 2010-12-07 Segetis, Inc. Method of making ketals and acetals
CN102239156B (zh) 2008-09-25 2014-10-15 塞格提斯有限公司 缩酮酯衍生物
BRPI1013943B1 (pt) 2009-06-22 2020-03-17 Segetis, Inc. Composto, método para sintetizar o mesmo, composição e composição lubrificante
CN102883705A (zh) 2010-05-10 2013-01-16 赛格提斯公司 含有烷基缩酮酯的个人护理制剂以及制造方法
AU2011285715B2 (en) 2010-08-03 2016-04-21 Gfbiochemicals Limited Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
US9074065B2 (en) 2010-08-12 2015-07-07 Segetis, Inc. Latex coating compositions including carboxy ester ketal coalescents, methods of manufacture, and uses thereof
CA2803389C (en) 2010-08-12 2016-10-11 Segetis, Inc. Carboxy ester ketal removal compositions, methods of manufacture, and uses thereof
US8632612B2 (en) 2010-09-07 2014-01-21 Segetis, Inc. Compositions for dyeing keratin fibers
CN103097604A (zh) 2010-09-13 2013-05-08 赛格提斯有限公司 织物软化剂组合物及其制造方法
KR20130131323A (ko) 2010-10-18 2013-12-03 세게티스, 인코포레이티드. 카복시 에스터 케탈을 포함하는 수희석성 코팅 조성물, 그리고 그의 제조방법 및 용도
US9458414B2 (en) 2012-09-21 2016-10-04 Gfbiochemicals Limited Cleaning, surfactant, and personal care compositions
BR112015012471B1 (pt) 2012-11-29 2020-05-19 Segetis Inc cetais de carbóxi éster , métodos de fabricação e uso dos mesmos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR4493M (enExample) * 1964-07-09 1966-10-10
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001158781A (ja) * 1999-10-06 2001-06-12 Dainippon Ink & Chem Inc 官能基を有する4−メチレン−1,3−ジオキソランおよびその製造方法

Also Published As

Publication number Publication date
AU2274188A (en) 1989-04-06
EP0308956A3 (en) 1990-06-13
NO171412C (no) 1993-03-10
FI884377A0 (fi) 1988-09-23
IL87800A (en) 1992-12-01
US4923891A (en) 1990-05-08
PT88580B (pt) 1992-11-30
FI884377L (fi) 1989-03-25
EP0308956B1 (en) 1993-03-03
NZ226318A (en) 1991-08-27
DK530888A (da) 1989-03-25
FI884377A7 (fi) 1989-03-25
EP0308956A2 (en) 1989-03-29
NO884223L (no) 1989-03-28
PT88580A (pt) 1988-10-01
KR890005082A (ko) 1989-05-11
GR3007858T3 (enExample) 1993-08-31
DK530888D0 (da) 1988-09-23
AU610246B2 (en) 1991-05-16
ES2045052T3 (es) 1994-01-16
DE3878806T2 (de) 1993-07-01
NO171412B (no) 1992-11-30
NO884223D0 (no) 1988-09-23
IL87800A0 (en) 1989-03-31
DE3878806D1 (de) 1993-04-08

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