PT88580A - Process for preparing 1,3-dithio(oxathio or dioxo)lane derivatives useful as leukotriene ltd4 and ltb4 antagonists - Google Patents

Process for preparing 1,3-dithio(oxathio or dioxo)lane derivatives useful as leukotriene ltd4 and ltb4 antagonists

Info

Publication number
PT88580A
PT88580A PT88580A PT8858088A PT88580A PT 88580 A PT88580 A PT 88580A PT 88580 A PT88580 A PT 88580A PT 8858088 A PT8858088 A PT 8858088A PT 88580 A PT88580 A PT 88580A
Authority
PT
Portugal
Prior art keywords
oxathio
dithio
dioxo
lane
preparing
Prior art date
Application number
PT88580A
Other languages
English (en)
Other versions
PT88580B (pt
Inventor
James Ronald Deason
Michael Allan Stealey
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT88580A publication Critical patent/PT88580A/pt
Publication of PT88580B publication Critical patent/PT88580B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT88580A 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 PT88580B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (2)

Publication Number Publication Date
PT88580A true PT88580A (pt) 1988-10-01
PT88580B PT88580B (pt) 1992-11-30

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88580A PT88580B (pt) 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4

Country Status (14)

Country Link
US (1) US4923891A (pt)
EP (1) EP0308956B1 (pt)
JP (1) JPH01132577A (pt)
KR (1) KR890005082A (pt)
AU (1) AU610246B2 (pt)
DE (1) DE3878806T2 (pt)
DK (1) DK530888A (pt)
ES (1) ES2045052T3 (pt)
FI (1) FI884377A (pt)
GR (1) GR3007858T3 (pt)
IL (1) IL87800A (pt)
NO (1) NO171412C (pt)
NZ (1) NZ226318A (pt)
PT (1) PT88580B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
US6342510B1 (en) 1995-06-12 2002-01-29 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
AU2250097A (en) 1996-02-13 1997-09-02 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist
DE69911020T2 (de) * 1999-10-06 2004-07-08 Dainippon Ink And Chemicals, Inc. 4-Methylen-1,3-dioxolane mit funktionellen Gruppen
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
CN101346067B (zh) 2005-11-22 2013-03-27 塞格提斯有限公司 甘油乙酰丙酸酯缩酮及其用途
WO2009048874A1 (en) * 2007-10-09 2009-04-16 Segetis, Inc. Method of making ketals and acetals
CN102239156B (zh) 2008-09-25 2014-10-15 塞格提斯有限公司 缩酮酯衍生物
CN102459219A (zh) 2009-06-22 2012-05-16 赛格提斯公司 缩酮化合物及其用途
CA2796883A1 (en) 2010-05-10 2011-11-17 Segetis, Inc. Personal care formulations containing alkyl ketal esters and methods of manufacture
CA2806352C (en) 2010-08-03 2019-09-24 Segetis, Inc. Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
CN103052691B (zh) 2010-08-12 2014-05-28 赛格提斯有限公司 包含羧基酯缩酮聚结物的胶乳涂层组合物、其制备方法和应用
WO2012021824A2 (en) 2010-08-12 2012-02-16 Segetis, Inc. Carboxy ester ketal removal compositions, methods of manufacture, and uses thereof
EP2613760A2 (en) 2010-09-07 2013-07-17 Segetis, Inc. Compositions for dyeing keratin fibers
WO2012037122A2 (en) 2010-09-13 2012-03-22 Segetis, Inc. Fabric softener compositions and methods of manufacture thereof
WO2012054505A2 (en) 2010-10-18 2012-04-26 Segetis, Inc. Water reducible coating compositions including carboxy ester ketals, methods of manufacture, and uses thereof
WO2014047428A1 (en) 2012-09-21 2014-03-27 Segetis, Inc. Cleaning, surfactant, and personal care compositions
WO2014085609A1 (en) 2012-11-29 2014-06-05 Segetis, Inc. Carboxy ester ketals, methods of manufacture, and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR4493M (pt) * 1964-07-09 1966-10-10
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
DE3878806T2 (de) 1993-07-01
PT88580B (pt) 1992-11-30
EP0308956A2 (en) 1989-03-29
DK530888A (da) 1989-03-25
GR3007858T3 (pt) 1993-08-31
NZ226318A (en) 1991-08-27
EP0308956A3 (en) 1990-06-13
US4923891A (en) 1990-05-08
AU2274188A (en) 1989-04-06
NO171412B (no) 1992-11-30
AU610246B2 (en) 1991-05-16
NO884223D0 (no) 1988-09-23
DE3878806D1 (de) 1993-04-08
KR890005082A (ko) 1989-05-11
EP0308956B1 (en) 1993-03-03
FI884377A (fi) 1989-03-25
NO884223L (no) 1989-03-28
ES2045052T3 (es) 1994-01-16
FI884377A0 (fi) 1988-09-23
IL87800A (en) 1992-12-01
IL87800A0 (en) 1989-03-31
JPH01132577A (ja) 1989-05-25
NO171412C (no) 1993-03-10
DK530888D0 (da) 1988-09-23

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920521

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941130