PT84339A - 1,6-naphthyridine derivatives process for the preparation thereof and pharmaceutical compositions containing them - Google Patents
1,6-naphthyridine derivatives process for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- PT84339A PT84339A PT84339A PT8433987A PT84339A PT 84339 A PT84339 A PT 84339A PT 84339 A PT84339 A PT 84339A PT 8433987 A PT8433987 A PT 8433987A PT 84339 A PT84339 A PT 84339A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- naphthyridine derivatives
- derivatives process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843431303 DE3431303A1 (de) | 1984-08-25 | 1984-08-25 | 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung |
DE19863605743 DE3605743A1 (de) | 1984-08-25 | 1986-02-22 | 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
PT84339A true PT84339A (pt) | 1987-03-01 |
PT84339B PT84339B (pt) | 1989-09-14 |
Family
ID=37877026
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT84339A PT84339B (pt) | 1984-08-25 | 1987-02-20 | Processo para a preparacao de derivados da 1,6-naftiridina e de composicoes farmaceuticas que os contem |
Country Status (11)
Country | Link |
---|---|
US (1) | US4751228A (pt) |
EP (1) | EP0234516B1 (pt) |
JP (2) | JPS61143382A (pt) |
DD (1) | DD236316A5 (pt) |
DE (2) | DE3431303A1 (pt) |
DK (1) | DK87687A (pt) |
ES (1) | ES2036533T3 (pt) |
GR (1) | GR3004468T3 (pt) |
IE (1) | IE59783B1 (pt) |
PT (1) | PT84339B (pt) |
ZA (1) | ZA856431B (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3906460C1 (pt) * | 1989-03-01 | 1990-11-15 | Goedecke Ag, 1000 Berlin, De | |
DE3906406C1 (pt) * | 1989-03-01 | 1990-10-25 | Goedecke Ag, 1000 Berlin, De | |
DE4202526A1 (de) * | 1992-01-30 | 1993-08-05 | Bayer Ag | Neue 4-cinnolinyl- und 4-naphthyridinyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DE102006026585A1 (de) * | 2006-06-07 | 2007-12-13 | Bayer Healthcare Aktiengesellschaft | Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung |
DE102006026583A1 (de) * | 2006-06-07 | 2007-12-13 | Bayer Healthcare Aktiengesellschaft | Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung |
DE102007009494A1 (de) * | 2007-02-27 | 2008-08-28 | Bayer Healthcare Ag | Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung |
PT3337801T (pt) * | 2015-08-21 | 2019-08-05 | Bayer Pharma AG | Processo para preparar (4s)-4-(4-ciano-2-metoxifenil)-5- etoxi-2,8-dimetil-1,4-di-hidro-1,6-naftiridina-3- carboxamida e recuperar (4s)-4-(4-ciano-2-metoxifenil)-5- etoxi-2,8-dimetil-1,4-di-hidro-1,6-naftiridina-3- carboxamida por meio de métodos eletroquímicos |
PE20180554A1 (es) * | 2015-08-21 | 2018-04-02 | Bayer Pharma AG | Procedimiento para la preparacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetilo-1,4-dihidro-1,6-naftiridina-3-carboxamida y su purificacion para su uso como principio activo farmaceutico |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5553291A (en) * | 1978-10-17 | 1980-04-18 | Nippon Kayaku Co Ltd | Naphthylidine derivative and its preparation |
DE3169626D1 (en) * | 1981-02-27 | 1985-05-02 | American Home Prod | Antihypertensive agents |
AU532361B2 (en) * | 1981-09-01 | 1983-09-29 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US4415580A (en) * | 1982-08-02 | 1983-11-15 | Sterling Drug Inc. | Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same |
DE3327650A1 (de) * | 1983-07-30 | 1985-02-14 | Gödecke AG, 1000 Berlin | 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen |
IL75987A (en) * | 1984-08-25 | 1991-07-18 | Goedecke Ag | Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them |
-
1984
- 1984-08-25 DE DE19843431303 patent/DE3431303A1/de active Granted
-
1985
- 1985-08-23 ZA ZA856431A patent/ZA856431B/xx unknown
- 1985-08-23 DD DD85279936A patent/DD236316A5/de not_active IP Right Cessation
- 1985-08-23 JP JP60185643A patent/JPS61143382A/ja active Granted
-
1986
- 1986-02-22 DE DE19863605743 patent/DE3605743A1/de not_active Withdrawn
-
1987
- 1987-01-28 US US07/007,691 patent/US4751228A/en not_active Expired - Fee Related
- 1987-02-20 JP JP62035940A patent/JPS62198680A/ja active Pending
- 1987-02-20 DK DK087687A patent/DK87687A/da not_active Application Discontinuation
- 1987-02-20 PT PT84339A patent/PT84339B/pt not_active IP Right Cessation
- 1987-02-20 EP EP87102398A patent/EP0234516B1/de not_active Expired - Lifetime
- 1987-02-20 IE IE43687A patent/IE59783B1/en not_active IP Right Cessation
- 1987-02-20 ES ES198787102398T patent/ES2036533T3/es not_active Expired - Lifetime
-
1992
- 1992-04-30 GR GR920400703T patent/GR3004468T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPS61143382A (ja) | 1986-07-01 |
DD236316A5 (de) | 1986-06-04 |
ES2036533T3 (es) | 1993-06-01 |
EP0234516B1 (de) | 1992-04-29 |
DE3431303C2 (pt) | 1989-08-10 |
JPH0360834B2 (pt) | 1991-09-17 |
DE3431303A1 (de) | 1986-02-27 |
EP0234516A1 (de) | 1987-09-02 |
DK87687A (da) | 1987-08-23 |
US4751228A (en) | 1988-06-14 |
IE870436L (en) | 1987-08-22 |
ZA856431B (en) | 1986-04-30 |
DE3605743A1 (de) | 1987-08-27 |
JPS62198680A (ja) | 1987-09-02 |
GR3004468T3 (pt) | 1993-03-31 |
DK87687D0 (da) | 1987-02-20 |
IE59783B1 (en) | 1994-04-06 |
PT84339B (pt) | 1989-09-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960831 |