DE3873720T2 - Nicotinoylpiperazin-derivate, verfahren zu ihrer herstellung und ihre verwendung in der therapie. - Google Patents

Nicotinoylpiperazin-derivate, verfahren zu ihrer herstellung und ihre verwendung in der therapie.

Info

Publication number
DE3873720T2
DE3873720T2 DE8888403182T DE3873720T DE3873720T2 DE 3873720 T2 DE3873720 T2 DE 3873720T2 DE 8888403182 T DE8888403182 T DE 8888403182T DE 3873720 T DE3873720 T DE 3873720T DE 3873720 T2 DE3873720 T2 DE 3873720T2
Authority
DE
Germany
Prior art keywords
nicotinoyl
addition salts
piperazine
formula
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888403182T
Other languages
German (de)
English (en)
Other versions
DE3873720D1 (de
Inventor
Bernard Danree
Michelle Faulques
Jean-Yves Lacolle
Jean-Pierre Riffaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Original Assignee
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA filed Critical Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Application granted granted Critical
Publication of DE3873720D1 publication Critical patent/DE3873720D1/de
Publication of DE3873720T2 publication Critical patent/DE3873720T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8888403182T 1987-12-16 1988-12-14 Nicotinoylpiperazin-derivate, verfahren zu ihrer herstellung und ihre verwendung in der therapie. Expired - Fee Related DE3873720T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8717563A FR2624857B1 (fr) 1987-12-16 1987-12-16 Derives de nicotinoyl-piperazine, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
DE3873720D1 DE3873720D1 (de) 1992-09-17
DE3873720T2 true DE3873720T2 (de) 1993-03-11

Family

ID=9357932

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888403182T Expired - Fee Related DE3873720T2 (de) 1987-12-16 1988-12-14 Nicotinoylpiperazin-derivate, verfahren zu ihrer herstellung und ihre verwendung in der therapie.

Country Status (11)

Country Link
US (1) US4880807A (enExample)
EP (1) EP0323303B1 (enExample)
JP (1) JPH01199947A (enExample)
AT (1) ATE79374T1 (enExample)
CA (1) CA1316926C (enExample)
DE (1) DE3873720T2 (enExample)
DK (1) DK169543B1 (enExample)
ES (1) ES2043873T3 (enExample)
FR (1) FR2624857B1 (enExample)
GR (1) GR3006202T3 (enExample)
PT (1) PT89216B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2956441A4 (en) * 2013-02-18 2016-11-02 Scripps Research Inst MODULATORS OF VASOPRESSIN RECEPTORS WITH THERAPEUTIC POTENTIAL

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE540697C (de) * 1925-08-11 1933-01-28 Chemische Ind Ges Verfahren zur Darstellung einseitig acylierter Diamine
BE795518A (fr) * 1972-02-17 1973-08-16 Ciba Geigy Nouveaux composes pyridiniques et leurs procedes de preparation
US3865828A (en) * 1972-03-22 1975-02-11 Egyt Gyogyszervegyeszeti Gyar Pyridine derivatives having antidepressant activity
CH653021A5 (fr) * 1981-04-24 1985-12-13 Delalande Sa Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
DE3601397A1 (de) * 1986-01-18 1987-07-23 Bayer Ag Substituierte 1,4-dihydropyridin-3-carbonsaeurepiperazide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
FR2624857B1 (fr) 1991-03-22
FR2624857A1 (fr) 1989-06-23
JPH01199947A (ja) 1989-08-11
CA1316926C (en) 1993-04-27
ATE79374T1 (de) 1992-08-15
EP0323303A1 (fr) 1989-07-05
ES2043873T3 (es) 1994-01-01
DK684888D0 (da) 1988-12-08
US4880807A (en) 1989-11-14
DK169543B1 (da) 1994-11-28
PT89216A (pt) 1989-12-29
DK684888A (da) 1989-06-17
PT89216B (pt) 1993-07-30
DE3873720D1 (de) 1992-09-17
GR3006202T3 (enExample) 1993-06-21
EP0323303B1 (fr) 1992-08-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee