DE3829028C2 - - Google Patents
Info
- Publication number
- DE3829028C2 DE3829028C2 DE3829028A DE3829028A DE3829028C2 DE 3829028 C2 DE3829028 C2 DE 3829028C2 DE 3829028 A DE3829028 A DE 3829028A DE 3829028 A DE3829028 A DE 3829028A DE 3829028 C2 DE3829028 C2 DE 3829028C2
- Authority
- DE
- Germany
- Prior art keywords
- plate
- cells
- receiving
- chambers
- chamber plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007853 buffer solution Substances 0.000 claims description 26
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000013078 crystal Substances 0.000 claims description 10
- 229910052710 silicon Inorganic materials 0.000 claims description 10
- 239000010703 silicon Substances 0.000 claims description 10
- 229910004298 SiO 2 Inorganic materials 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- 210000004027 cell Anatomy 0.000 description 62
- 230000007910 cell fusion Effects 0.000 description 7
- 210000001938 protoplast Anatomy 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- 230000032258 transport Effects 0.000 description 5
- 108010039918 Polylysine Proteins 0.000 description 3
- 239000002156 adsorbate Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229920000656 polylysine Polymers 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 210000004102 animal cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000001912 transporting cell Anatomy 0.000 description 1
- 235000012431 wafers Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Cell Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62215288A JP2559760B2 (ja) | 1987-08-31 | 1987-08-31 | 細胞搬送方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3829028A1 DE3829028A1 (de) | 1989-03-09 |
| DE3829028C2 true DE3829028C2 (enExample) | 1992-04-16 |
Family
ID=16669837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3829028A Granted DE3829028A1 (de) | 1987-08-31 | 1988-08-26 | Zellenhandhabungsvorrichtung |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4895805A (enExample) |
| JP (1) | JP2559760B2 (enExample) |
| DE (1) | DE3829028A1 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2564322B2 (ja) * | 1987-10-07 | 1996-12-18 | 株式会社日立製作所 | 細胞融合装置 |
| US5183744A (en) * | 1988-10-26 | 1993-02-02 | Hitachi, Ltd. | Cell handling method for cell fusion processor |
| FR2659347B1 (fr) * | 1990-03-12 | 1994-09-02 | Agronomique Inst Nat Rech | Dispositif de culture de cellules assurant leur immobilisation. |
| JP2966904B2 (ja) * | 1990-08-08 | 1999-10-25 | 株式会社日立製作所 | 細胞の処理方法、および処理装置 |
| DK0503128T3 (da) * | 1991-03-13 | 1996-02-12 | Cytyc Corp | Apparat til indsamling og overførsel af partikler og fremstilling af et sådant apparat |
| US5364597A (en) * | 1991-03-13 | 1994-11-15 | Cytyc Corporation | Apparatus for collection and transfer of particles |
| US5674394A (en) * | 1995-03-24 | 1997-10-07 | Johnson & Johnson Medical, Inc. | Single use system for preparation of autologous plasma |
| US5820767A (en) * | 1996-07-29 | 1998-10-13 | Pall Corporation | Method for quantitation of microorganism contamination of liquids |
| NL1007489C2 (nl) * | 1996-11-08 | 2000-10-24 | Konink Grolsch N V | Werkwijze en inrichting voor het in een medium aantonen van micro-organismen. |
| WO1998022819A1 (de) * | 1996-11-16 | 1998-05-28 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen In Reutlingen Stiftung Bürgerlichen Rechts | Mikroelementenanordnung, verfahren zum kontaktieren von in einer flüssigen umgebung befindlichen zellen und verfahren zum herstellen einer mikroelementenanordnung |
| US6210910B1 (en) | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
| EP2360271A1 (en) | 1998-06-24 | 2011-08-24 | Illumina, Inc. | Decoding of array sensors with microspheres |
| GB2352652A (en) * | 1999-08-06 | 2001-02-07 | Fsm Technologies Ltd | Pre-treating hollow fibre membranes for micro-organism detection |
| GB9925904D0 (en) | 1999-11-03 | 1999-12-29 | Univ Belfast | Cell migration and chemotaxis chamber |
| US6692952B1 (en) * | 1999-11-10 | 2004-02-17 | Massachusetts Institute Of Technology | Cell analysis and sorting apparatus for manipulation of cells |
| US6994781B2 (en) * | 2000-07-07 | 2006-02-07 | Baxter International Inc. | Medical system, method and apparatus employing MEMS |
| EP1319181A2 (en) * | 2000-09-05 | 2003-06-18 | Illumina, Inc. | Cellular arrays comprising encoded cells |
| US7123764B2 (en) * | 2000-11-08 | 2006-10-17 | Surface Logix Inc. | Image processing method for use in analyzing data of a chemotaxis or haptotaxis assay |
| JP3738899B2 (ja) * | 2000-12-07 | 2006-01-25 | 株式会社 エフェクター細胞研究所 | 微量試料処理装置 |
| TWI241343B (en) | 2000-12-07 | 2005-10-11 | Effector Cell Inst Inc | Well unit for detecting cell chemotaxis and separating chemotactic cells |
| US20050014201A1 (en) * | 2001-10-25 | 2005-01-20 | Mordechai Deuthsch | Interactive transparent individual cells biochip processor |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| CA2511724A1 (en) * | 2002-12-23 | 2004-07-08 | Unisense A/S | Device and method for non-invasive measurement of the individual metabolic rate of a substantially spherical metabolizing particle |
| WO2004065000A1 (en) * | 2003-01-21 | 2004-08-05 | Illumina Inc. | Chemical reaction monitor |
| IL154677A0 (en) * | 2003-02-27 | 2003-09-17 | Univ Bar Ilan | A method and apparatus for manipulating an individual cell |
| EP1604184A4 (en) * | 2003-02-27 | 2010-10-27 | Stephen A Lesko | STANDARDIZED EVALUATION OF THERAPEUTIC EFFICIENCY BASED ON CELLULAR BIOMARKERS |
| TW200506364A (en) * | 2003-04-09 | 2005-02-16 | Effector Cell Inst Inc | Apparatus for detecting cell chemo-taxis |
| WO2004113877A1 (en) * | 2003-06-13 | 2004-12-29 | The General Hospital Corporation | Microfluidic systems for size based removal of red blood cells and platelets from blood |
| US9200245B2 (en) * | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
| EP1654347B1 (en) * | 2003-06-26 | 2014-06-04 | Seng Enterprises Limited | Improved materials for constructing cell-chips, cell-chip covers, cell-chip coats, processed cell-chips and uses thereof |
| US8597597B2 (en) * | 2003-06-26 | 2013-12-03 | Seng Enterprises Ltd. | Picoliter well holding device and method of making the same |
| JP4555650B2 (ja) * | 2004-09-29 | 2010-10-06 | 富士通株式会社 | 細胞給排・捕捉装置及び細胞給排・捕捉方法 |
| US20060134772A1 (en) * | 2004-11-18 | 2006-06-22 | The Regents Of The University Of California | System for locating cells and for cellular analysis |
| JP2006149227A (ja) * | 2004-11-25 | 2006-06-15 | Fujitsu Ltd | 微小物体の捕獲装置及び方法 |
| JP2006149226A (ja) * | 2004-11-25 | 2006-06-15 | Fujitsu Ltd | 微小物体の捕獲装置及び方法 |
| ATE480324T1 (de) | 2005-01-25 | 2010-09-15 | Seng Entpr Ltd | Mikrofluidische vorrichtung zur untersuchung zellen |
| JP4894199B2 (ja) * | 2005-02-17 | 2012-03-14 | 富士通株式会社 | 物質注入装置 |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US20060246571A1 (en) * | 2005-04-29 | 2006-11-02 | Fujitsu Limited | Apparatus and method for automatically producing substance-introduced particles |
| US8921102B2 (en) * | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| JP5451073B2 (ja) * | 2005-10-14 | 2014-03-26 | ユニセンス・ファーティリテック・アクティーゼルスカブ | 細胞集団における変化の決定 |
| WO2007052245A1 (en) * | 2005-11-03 | 2007-05-10 | Seng Enterprises Ltd. | Method and device for studying floating, living cells |
| DK2035548T3 (da) * | 2006-06-16 | 2010-11-22 | Unisense Fertilitech As | Vurdering af embryokvalitet på basis af blastomer deling og bevævgelse |
| JP5205798B2 (ja) | 2007-04-27 | 2013-06-05 | 富士通株式会社 | マイクロインジェクション装置、捕捉プレート、およびマイクロインジェクション方法 |
| JP2008295376A (ja) * | 2007-05-31 | 2008-12-11 | Fujitsu Ltd | 細胞捕捉プレート、マイクロインジェクション装置、および細胞捕捉プレートの製造方法 |
| CN103642688B (zh) * | 2007-06-29 | 2018-05-01 | 尤尼森斯繁殖技术公司 | 用于监测和/或培养显微对象的设备、系统和方法 |
| US9145540B1 (en) | 2007-11-15 | 2015-09-29 | Seng Enterprises Ltd. | Device for the study of living cells |
| US9975118B2 (en) * | 2007-11-15 | 2018-05-22 | Seng Enterprises Ltd. | Device for the study of living cells |
| JP2011526782A (ja) * | 2008-07-05 | 2011-10-20 | ウニセンス フェルティリテック アー/エス | 1対1識別システム |
| CN102097385B (zh) * | 2009-12-15 | 2014-05-07 | 中芯国际集成电路制造(上海)有限公司 | 双位快闪存储器的制作方法 |
| US8187979B2 (en) * | 2009-12-23 | 2012-05-29 | Varian Semiconductor Equipment Associates, Inc. | Workpiece patterning with plasma sheath modulation |
| JP5487152B2 (ja) * | 2011-04-11 | 2014-05-07 | 株式会社日立製作所 | 細胞採取システム |
| WO2015093116A1 (ja) * | 2013-12-17 | 2015-06-25 | コニカミノルタ株式会社 | 細胞の蛍光免疫染色方法ならびにそのためのシステムおよびキット |
| WO2019049944A1 (en) * | 2017-09-07 | 2019-03-14 | Sony Corporation | PARTICLE CAPTURE CHAMBER, PARTICLE CAPTURE CHIP, PARTICLE CAPTURE METHOD, APPARATUS, AND PARTICLE ANALYSIS SYSTEM |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4272510A (en) * | 1976-04-26 | 1981-06-09 | Smith Kendall O | Magnetic attraction transfer process for use in solid phase radioimmunoassays and in other assay methods |
| DE2741638C3 (de) * | 1977-09-15 | 1980-03-27 | Ernst Dipl.-Phys. Dr. 8000 Muenchen Remy | Präparattrager mit Elektrodenanordnung fur die Zelluntersuchung, sowie seine Herstellung |
| US4252897A (en) * | 1978-05-03 | 1981-02-24 | Axford Herbert George | Method and apparatus for bacteria testing |
| DE3368534D1 (en) * | 1982-03-03 | 1987-02-05 | Becton Dickinson Co | Multi-well screening assembly for immunoassay procedures |
| IL68507A (en) * | 1982-05-10 | 1986-01-31 | Univ Bar Ilan | System and methods for cell selection |
| JPH06232874A (ja) * | 1993-02-01 | 1994-08-19 | Hitachi Ltd | ブリッジにおけるデータ伝送方式 |
-
1987
- 1987-08-31 JP JP62215288A patent/JP2559760B2/ja not_active Expired - Lifetime
-
1988
- 1988-08-24 US US07/235,485 patent/US4895805A/en not_active Expired - Fee Related
- 1988-08-26 DE DE3829028A patent/DE3829028A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4895805A (en) | 1990-01-23 |
| DE3829028A1 (de) | 1989-03-09 |
| JP2559760B2 (ja) | 1996-12-04 |
| JPS6460365A (en) | 1989-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |