DE3720681A1 - 1-methansulfonyloxy- und p-toluolsulfonyloxy-6-trifluormethyl-1h-benzotriazol, 2-heterocyclyl-2-syn-oxyiminoessigsaeure-5-trifluormethyl-1h-benzotriazol-1-yl-ester und deren verwendung zur herstellung von cephalosporinderivaten - Google Patents

1-methansulfonyloxy- und p-toluolsulfonyloxy-6-trifluormethyl-1h-benzotriazol, 2-heterocyclyl-2-syn-oxyiminoessigsaeure-5-trifluormethyl-1h-benzotriazol-1-yl-ester und deren verwendung zur herstellung von cephalosporinderivaten

Info

Publication number
DE3720681A1
DE3720681A1 DE19873720681 DE3720681A DE3720681A1 DE 3720681 A1 DE3720681 A1 DE 3720681A1 DE 19873720681 DE19873720681 DE 19873720681 DE 3720681 A DE3720681 A DE 3720681A DE 3720681 A1 DE3720681 A1 DE 3720681A1
Authority
DE
Germany
Prior art keywords
general formula
syn
mmol
benzotriazole
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19873720681
Other languages
German (de)
English (en)
Inventor
Dae Hwang Kim
Cheol Hae Lee
Kyung Sook Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Chemical Technology KRICT
Original Assignee
Korea Research Institute of Chemical Technology KRICT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Chemical Technology KRICT filed Critical Korea Research Institute of Chemical Technology KRICT
Publication of DE3720681A1 publication Critical patent/DE3720681A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE19873720681 1986-06-25 1987-06-23 1-methansulfonyloxy- und p-toluolsulfonyloxy-6-trifluormethyl-1h-benzotriazol, 2-heterocyclyl-2-syn-oxyiminoessigsaeure-5-trifluormethyl-1h-benzotriazol-1-yl-ester und deren verwendung zur herstellung von cephalosporinderivaten Withdrawn DE3720681A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019860005101A KR890002107B1 (ko) 1986-06-25 1986-06-25 세팔로스포린 유도체의 제조방법

Publications (1)

Publication Number Publication Date
DE3720681A1 true DE3720681A1 (de) 1988-01-28

Family

ID=19250716

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19873720681 Withdrawn DE3720681A1 (de) 1986-06-25 1987-06-23 1-methansulfonyloxy- und p-toluolsulfonyloxy-6-trifluormethyl-1h-benzotriazol, 2-heterocyclyl-2-syn-oxyiminoessigsaeure-5-trifluormethyl-1h-benzotriazol-1-yl-ester und deren verwendung zur herstellung von cephalosporinderivaten
DE19873744772 Pending DE3744772A1 (OSRAM) 1986-06-25 1987-06-23

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19873744772 Pending DE3744772A1 (OSRAM) 1986-06-25 1987-06-23

Country Status (5)

Country Link
JP (1) JPS6322570A (OSRAM)
KR (1) KR890002107B1 (OSRAM)
DE (2) DE3720681A1 (OSRAM)
GB (1) GB2195334A (OSRAM)
IT (1) IT1205178B (OSRAM)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR890100706A (el) * 1989-10-31 1992-03-20 Han Mi Pharma Ind Co Ltd Μέ?οδος παρασκευής παραγώγων κεφέμης.
EP0556768A3 (en) * 1992-02-20 1993-11-24 Biochemie Gmbh New process for the production of ceftriaxone
EP0553792A3 (en) * 1992-01-28 1993-12-29 Lek Tovarna Farmacevtskih Process for the preparation of the disodium salt hemiheptahydrate of ceftriaxone
WO1996012712A1 (en) * 1994-10-24 1996-05-02 Miwon Co., Ltd. Reactive phosphate derivatives of thiazolylacetic acid and process for preparing cephalosporin antibiotics using the same
FR2736054A1 (fr) * 1995-06-30 1997-01-03 Chong Kun Dang Corp Procede de fabrication de derives cephemes

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR890100706A (el) * 1989-10-31 1992-03-20 Han Mi Pharma Ind Co Ltd Μέ?οδος παρασκευής παραγώγων κεφέμης.
EP0553792A3 (en) * 1992-01-28 1993-12-29 Lek Tovarna Farmacevtskih Process for the preparation of the disodium salt hemiheptahydrate of ceftriaxone
EP0556768A3 (en) * 1992-02-20 1993-11-24 Biochemie Gmbh New process for the production of ceftriaxone
US5574155A (en) * 1992-02-20 1996-11-12 Biochemie Gesellschaft M.B.H. Process for the synthesis of the disodium salt hemiheptahydrate of ceftriaxone
WO1996012712A1 (en) * 1994-10-24 1996-05-02 Miwon Co., Ltd. Reactive phosphate derivatives of thiazolylacetic acid and process for preparing cephalosporin antibiotics using the same
FR2736054A1 (fr) * 1995-06-30 1997-01-03 Chong Kun Dang Corp Procede de fabrication de derives cephemes

Also Published As

Publication number Publication date
KR880000448A (ko) 1988-03-25
GB8714764D0 (en) 1987-07-29
JPS6322570A (ja) 1988-01-30
IT8721014A0 (it) 1987-06-23
GB2195334A (en) 1988-04-07
KR890002107B1 (ko) 1989-06-19
IT1205178B (it) 1989-03-15
DE3744772A1 (OSRAM) 1989-02-02

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