DE3687467T2 - Komplexe von technetium-99m mit propylen-amin-oximen. - Google Patents

Komplexe von technetium-99m mit propylen-amin-oximen.

Info

Publication number
DE3687467T2
DE3687467T2 DE8686301708T DE3687467T DE3687467T2 DE 3687467 T2 DE3687467 T2 DE 3687467T2 DE 8686301708 T DE8686301708 T DE 8686301708T DE 3687467 T DE3687467 T DE 3687467T DE 3687467 T2 DE3687467 T2 DE 3687467T2
Authority
DE
Germany
Prior art keywords
technetium
complexes
propylene amine
oximes
amine oximes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686301708T
Other languages
English (en)
Other versions
DE3687467D1 (de
Inventor
Lewis Rueben Canning
David Peter Nowotnik
Rudi Dominique Neirinckx
Ian Michael Piper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506249A external-priority patent/GB8506249D0/en
Priority claimed from GB858509368A external-priority patent/GB8509368D0/en
Application filed by Amersham International PLC filed Critical Amersham International PLC
Publication of DE3687467D1 publication Critical patent/DE3687467D1/de
Application granted granted Critical
Publication of DE3687467T2 publication Critical patent/DE3687467T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE8686301708T 1985-03-11 1986-03-10 Komplexe von technetium-99m mit propylen-amin-oximen. Expired - Lifetime DE3687467T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858506249A GB8506249D0 (en) 1985-03-11 1985-03-11 Complexes of technetium-99m
GB858509368A GB8509368D0 (en) 1985-04-12 1985-04-12 Complexes of technetium ggm

Publications (2)

Publication Number Publication Date
DE3687467D1 DE3687467D1 (de) 1993-02-25
DE3687467T2 true DE3687467T2 (de) 1993-04-29

Family

ID=26288959

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686301708T Expired - Lifetime DE3687467T2 (de) 1985-03-11 1986-03-10 Komplexe von technetium-99m mit propylen-amin-oximen.

Country Status (7)

Country Link
US (1) US4789736A (de)
EP (1) EP0194843B1 (de)
JP (2) JPH0676363B2 (de)
AU (1) AU577931B2 (de)
CA (1) CA1243329A (de)
DE (1) DE3687467T2 (de)
HK (1) HK97997A (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601003D0 (en) * 1986-01-16 1986-02-19 Amersham Int Plc Labelling blood cells
GB8702062D0 (en) * 1987-01-30 1987-03-04 Amersham Int Plc Metal complexes for diagnosis & therapy
US4895960A (en) * 1989-01-23 1990-01-23 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
US5026829A (en) * 1989-01-23 1991-06-25 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
US5026913A (en) * 1989-12-12 1991-06-25 Medi-Physics, Inc. Hydrocarbylphenyl diaminodithiol derivatives
US5080884A (en) * 1989-12-12 1992-01-14 Medi-Physics, Inc. Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging
ATE170757T1 (de) * 1990-04-17 1998-09-15 Mallinckrodt Medical Inc Methode und reagentien um technetium-99m-komplexe herzustellen
US5143713A (en) * 1990-05-30 1992-09-01 Board Of Regents, The University Of Texas System 99m Tc labeled liposomes
US5158760A (en) * 1990-05-30 1992-10-27 Board Of Regents, The University Of Texas System 99m TC labeled liposomes
US5252721A (en) * 1990-09-28 1993-10-12 Neorx Corporation S3 N chelating compounds
US5684137A (en) * 1990-09-28 1997-11-04 Neorx Corporation S3 N chelating compounds for the radiolabeling of ligands, anti-ligands or other proteins
US5116598A (en) * 1990-10-29 1992-05-26 Mallinckrodt Medical, Inc. N4 technetium-99 m complexes for use as radiopharmaceuticals
DE4107571A1 (de) * 1991-03-07 1992-11-19 Diagnostikforschung Inst Amid-chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie
DE4107570A1 (de) * 1991-03-07 1992-11-19 Diagnostikforschung Inst Chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie
IL103353A (en) * 1991-10-29 1999-01-26 Bracco Int Bv His metal bracelet ligand is a diagnostic product and processes for its preparation
US5808091A (en) 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
US6359120B1 (en) * 1991-10-29 2002-03-19 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia-localizing moiety
JP3953509B2 (ja) * 1992-10-08 2007-08-08 ジーイー・ヘルスケア・リミテッド 放射性薬剤として使用する金属オキシムキレート
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
JP3083157B2 (ja) * 1993-08-04 2000-09-04 アマーシャム・インターナショナル・ピーエルシー 酸素欠乏性組織に局在する放射性金属錯体
KR960700986A (ko) * 1994-01-12 1996-02-24 네나드 토모브-그리소고노 리간드 및 이들의 금속착체(ligands and metal complexes thereof)
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
WO1997019705A1 (en) * 1995-12-01 1997-06-05 Elmaleh David R Stereoisomers of fatty acid analogs for diagnostic imaging
US6005083A (en) 1997-03-28 1999-12-21 Neorx Corporation Bridged aromatic substituted amine ligands with donor atoms
KR100632963B1 (ko) * 1999-01-15 2006-10-11 동아제약주식회사 광학활성을갖는(3알,9알)또는(3에스,9에스)-4,8-디아자-3,6,6,9-테트라메틸운데칸-2,10-디온비스옥심유도체의제조방법
KR100615893B1 (ko) * 1999-01-15 2006-08-25 동아제약주식회사 (알알, 에스에스)-4,8-디아자-3,6,6,9-테트라메틸운데칸-2,10-디
AU5905400A (en) 1999-07-14 2001-02-05 Board Of Regents, The University Of Texas System Methods and compositions for delivery and retention of active agents to lymph nodes
US20090187060A1 (en) * 2008-01-22 2009-07-23 E-Z-Em, Inc. Method and Formulation for Neutralizing Toxic Chemicals and Materials
CU23844B1 (es) 2009-04-17 2012-10-15 Ct De Neurociencias De Cuba Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer
CA2942280C (en) * 2014-03-27 2022-11-29 Jubilant Life Sciences Limited An improved process for the preparation of exametazime

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
JPS60238575A (ja) * 1984-05-08 1985-11-27 三菱プレシジヨン株式会社 油圧駆動式昇降階段装置
GB8426845D0 (en) * 1984-10-24 1984-11-28 Amersham Int Plc Complexes of technetium-99m

Also Published As

Publication number Publication date
EP0194843A3 (en) 1988-03-23
JPH0676363B2 (ja) 1994-09-28
AU577931B2 (en) 1988-10-06
JP2547515B2 (ja) 1996-10-23
CA1243329A (en) 1988-10-18
HK97997A (en) 1997-08-08
CA1252481C (de) 1989-04-11
EP0194843A2 (de) 1986-09-17
US4789736A (en) 1988-12-06
DE3687467D1 (de) 1993-02-25
AU5460986A (en) 1986-10-16
JPH06184078A (ja) 1994-07-05
JPS61225159A (ja) 1986-10-06
EP0194843B1 (de) 1993-01-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS RECHTSANWAELTE PATENTANWAELTE, 80539 MUENCHEN