DE3683711D1 - Substituierte verbrueckte diabicycloalkylchinoloncarbonsaeure. - Google Patents

Substituierte verbrueckte diabicycloalkylchinoloncarbonsaeure.

Info

Publication number
DE3683711D1
DE3683711D1 DE8686307045T DE3683711T DE3683711D1 DE 3683711 D1 DE3683711 D1 DE 3683711D1 DE 8686307045 T DE8686307045 T DE 8686307045T DE 3683711 T DE3683711 T DE 3683711T DE 3683711 D1 DE3683711 D1 DE 3683711D1
Authority
DE
Germany
Prior art keywords
diabicycloalkylchinoloncarbonic
acids
substituted bridged
alkyl
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686307045T
Other languages
German (de)
English (en)
Inventor
Martin Raymond Jefson
Paul Robert Mcguirk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Inc
Original Assignee
Pfizer Corp Belgium
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Inc filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of DE3683711D1 publication Critical patent/DE3683711D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8686307045T 1985-09-18 1986-09-12 Substituierte verbrueckte diabicycloalkylchinoloncarbonsaeure. Expired - Lifetime DE3683711D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77747185A 1985-09-18 1985-09-18

Publications (1)

Publication Number Publication Date
DE3683711D1 true DE3683711D1 (de) 1992-03-12

Family

ID=25110350

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8686307045T Expired - Lifetime DE3683711D1 (de) 1985-09-18 1986-09-12 Substituierte verbrueckte diabicycloalkylchinoloncarbonsaeure.
DE1996175019 Active DE19675019I2 (de) 1985-09-18 1986-09-12 Substituierte verbrückte Diabicycloalkylchinoloncarbonsäure.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1996175019 Active DE19675019I2 (de) 1985-09-18 1986-09-12 Substituierte verbrückte Diabicycloalkylchinoloncarbonsäure.

Country Status (42)

Country Link
US (3) US4861779A (enExample)
EP (1) EP0215650B1 (enExample)
JP (1) JPH0798819B2 (enExample)
KR (1) KR870000961B1 (enExample)
CN (1) CN1014789B (enExample)
AT (1) ATE72245T1 (enExample)
AU (1) AU576302B2 (enExample)
BG (2) BG49275A3 (enExample)
CA (1) CA1340734C (enExample)
CY (1) CY1774A (enExample)
CZ (1) CZ277825B6 (enExample)
DD (1) DD259190A5 (enExample)
DE (2) DE3683711D1 (enExample)
DK (1) DK171276B1 (enExample)
EG (1) EG18184A (enExample)
ES (1) ES2001428A6 (enExample)
FI (1) FI87565C (enExample)
GR (1) GR862363B (enExample)
HK (1) HK132795A (enExample)
HU (1) HU200462B (enExample)
IE (1) IE58966B1 (enExample)
IL (1) IL80033A (enExample)
IN (1) IN166416B (enExample)
LU (1) LU90356I2 (enExample)
MA (1) MA20770A1 (enExample)
MW (1) MW5886A1 (enExample)
MX (1) MX173358B (enExample)
MY (1) MY102518A (enExample)
NO (1) NO170335C (enExample)
NZ (1) NZ217614A (enExample)
OA (1) OA08410A (enExample)
PH (2) PH24048A (enExample)
PL (1) PL149987B1 (enExample)
PT (1) PT83388B (enExample)
SG (1) SG28094G (enExample)
SK (1) SK667886A3 (enExample)
SU (1) SU1482531A3 (enExample)
UA (1) UA6340A1 (enExample)
YU (1) YU45024B (enExample)
ZA (1) ZA867063B (enExample)
ZM (1) ZM8586A1 (enExample)
ZW (1) ZW19386A1 (enExample)

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US4923879A (en) * 1987-07-31 1990-05-08 Warner-Lambert Company 1,8-Naphthyridines and their use as antibacterial agents
US4992546A (en) * 1987-07-31 1991-02-12 Warner-Lambert Company Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives
US4968799A (en) * 1987-07-31 1990-11-06 Warner-Lambert Company Antibacterial agents
US4933335A (en) * 1987-08-07 1990-06-12 Warner-Lambert Company Quinolones as antibacterial agents
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US5147873A (en) * 1988-08-23 1992-09-15 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
WO1990002123A1 (en) * 1988-08-23 1990-03-08 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
US4895943A (en) * 1988-10-25 1990-01-23 Pfizer Inc. Preparation of 1,4-diazabicyclo(3.2.2)nonane
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US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids
NZ513575A (en) * 1999-05-04 2003-07-25 Neurosearch As Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators
FR2809732B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
DE60202667T2 (de) * 2001-03-02 2005-06-16 Neurosearch A/S Neue 2,5-diazabicyclo [2.2.1] heptanderivate
BR0314201A (pt) * 2002-09-10 2005-07-12 Pfizer Prod Inc Compostos diazabicìclicos úteis no tratamento de doenças do cns e outros distúrbios
SK288115B6 (sk) * 2002-09-25 2013-09-03 Memory Pharmaceuticals Corporation Indazoles, pharmaceutical compositions comprising them and their use
DE10312346A1 (de) * 2003-03-20 2004-09-30 Bayer Healthcare Ag Kontrolliertes Freisetzungssystem
DE10351448A1 (de) 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
EP1697378B1 (en) * 2003-12-22 2007-11-21 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
EP2336128A1 (en) 2004-03-25 2011-06-22 Memory Pharmaceuticals Corporation Benzoisothiazoles and preparation and uses thereof
WO2006001894A1 (en) * 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
NZ551712A (en) * 2004-05-07 2010-07-30 Memory Pharm Corp 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparations and uses thereof
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
ES2342675T3 (es) 2004-12-22 2010-07-12 Memory Pharmaceuticals Corporation Ligandos del receptor alfa-7 nicotinico contra enfermedades relacionadas con el snc.
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
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EP1987031A1 (en) 2006-02-10 2008-11-05 NeuroSearch A/S 3-heteroaryl- 3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists
CA2641683A1 (en) 2006-02-10 2007-08-16 Neurosearch A/S 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
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DE102007055341A1 (de) * 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
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Also Published As

Publication number Publication date
NO863718L (no) 1987-03-19
CZ667886A3 (en) 1993-02-17
BG49275A3 (en) 1991-09-16
SG28094G (en) 1994-10-28
AU6276886A (en) 1987-03-19
ZM8586A1 (en) 1987-03-27
PT83388A (en) 1986-10-01
DE19675019I2 (de) 2004-01-29
KR870000961B1 (ko) 1987-05-14
IE862479L (en) 1987-03-18
BG61091B2 (bg) 1996-10-31
YU161786A (en) 1987-10-31
AU576302B2 (en) 1988-08-18
MY102518A (en) 1992-07-31
UA6340A1 (uk) 1994-12-29
CY1774A (en) 1995-10-20
EP0215650A3 (en) 1987-12-02
HUT43070A (en) 1987-09-28
PL261410A1 (en) 1987-11-16
ZW19386A1 (en) 1986-12-10
PH25338A (en) 1991-04-30
SK278605B6 (en) 1997-11-05
ZA867063B (en) 1988-04-27
FI87565C (fi) 1993-01-25
NO170335B (no) 1992-06-29
KR870003106A (ko) 1987-04-15
DK445886A (da) 1987-05-27
JPS62103083A (ja) 1987-05-13
US4775668A (en) 1988-10-04
IL80033A (en) 1992-05-25
DK171276B1 (da) 1996-08-19
DD259190A5 (de) 1988-08-17
US5091383A (en) 1992-02-25
SK667886A3 (en) 1997-11-05
CN1014789B (zh) 1991-11-20
NO863718D0 (no) 1986-09-17
EG18184A (en) 1992-12-30
IL80033A0 (en) 1986-12-31
FI863756A0 (fi) 1986-09-17
IE58966B1 (en) 1993-12-01
JPH0798819B2 (ja) 1995-10-25
CA1340734C (en) 1999-09-14
FI863756L (fi) 1987-03-19
MX3751A (es) 1993-09-01
MW5886A1 (en) 1987-12-09
PT83388B (pt) 1989-05-12
LU90356I2 (fr) 1999-04-26
YU45024B (en) 1991-06-30
IN166416B (enExample) 1990-05-05
ES2001428A6 (es) 1988-05-16
HU200462B (en) 1990-06-28
SU1482531A3 (ru) 1989-05-23
US4861779A (en) 1989-08-29
EP0215650A2 (en) 1987-03-25
CN86106385A (zh) 1987-06-03
FI87565B (fi) 1992-10-15
MA20770A1 (fr) 1987-04-01
NO170335C (no) 1992-10-07
MX173358B (es) 1994-02-23
OA08410A (fr) 1988-06-30
CZ277825B6 (en) 1993-06-16
NZ217614A (en) 1989-11-28
EP0215650B1 (en) 1992-01-29
GR862363B (en) 1987-01-19
PH24048A (en) 1990-03-05
HK132795A (en) 1995-09-01
ATE72245T1 (de) 1992-02-15
PL149987B1 (en) 1990-04-30
DK445886D0 (da) 1986-09-17

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