DE3650536D1 - Mittels rekombinanter DNS-Techniken gebildetes Hepatitis-B-Oberflächenantigen, Impfstoffe, Diagnostika, Zellinien und Verfahren zu deren Herstellung - Google Patents

Mittels rekombinanter DNS-Techniken gebildetes Hepatitis-B-Oberflächenantigen, Impfstoffe, Diagnostika, Zellinien und Verfahren zu deren Herstellung

Info

Publication number
DE3650536D1
DE3650536D1 DE3650536T DE3650536T DE3650536D1 DE 3650536 D1 DE3650536 D1 DE 3650536D1 DE 3650536 T DE3650536 T DE 3650536T DE 3650536 T DE3650536 T DE 3650536T DE 3650536 D1 DE3650536 D1 DE 3650536D1
Authority
DE
Germany
Prior art keywords
vaccines
diagnostics
hepatitis
processes
cell lines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3650536T
Other languages
English (en)
Other versions
DE3650536T2 (de
Inventor
John S Salstrom
Mark L Rohrbaugh
Hans A Thoma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Application granted granted Critical
Publication of DE3650536D1 publication Critical patent/DE3650536D1/de
Publication of DE3650536T2 publication Critical patent/DE3650536T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G01N33/5764—Hepatitis B surface antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE3650536T 1985-04-15 1986-04-15 Mittels rekombinanter DNS-Techniken gebildetes Hepatitis-B-Oberflächenantigen, Impfstoffe, Diagnostika, Zellinien und Verfahren zu deren Herstellung Expired - Fee Related DE3650536T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP85104521 1985-04-15

Publications (2)

Publication Number Publication Date
DE3650536D1 true DE3650536D1 (de) 1996-08-01
DE3650536T2 DE3650536T2 (de) 1997-02-27

Family

ID=8193449

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3650536T Expired - Fee Related DE3650536T2 (de) 1985-04-15 1986-04-15 Mittels rekombinanter DNS-Techniken gebildetes Hepatitis-B-Oberflächenantigen, Impfstoffe, Diagnostika, Zellinien und Verfahren zu deren Herstellung

Country Status (14)

Country Link
EP (2) EP0198474B1 (de)
JP (1) JPS6255088A (de)
CN (1) CN86102640A (de)
AP (1) AP8600035A0 (de)
AT (1) ATE139795T1 (de)
DE (1) DE3650536T2 (de)
ES (1) ES8802440A1 (de)
FI (1) FI861417A0 (de)
HK (1) HK1003794A1 (de)
IE (1) IE75355B1 (de)
IL (1) IL78472A (de)
SG (1) SG43220A1 (de)
YU (1) YU60986A (de)
ZA (1) ZA862797B (de)

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IL79740A0 (en) * 1986-08-17 1986-11-30 Yeda Res & Dev Hepatitis vaccine
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
EP0288198A3 (de) * 1987-04-20 1989-03-29 Takeda Chemical Industries, Ltd. Peptidherstellung
ES2094720T3 (es) * 1987-05-01 1997-02-01 Gen Hospital Corp Implantacion transcariotica.
EP0304578B1 (de) * 1987-06-22 2001-10-24 Medeva Holdings Bv Hepatitis-B-Oberflächenantigen enthaltendes Peptid
ATE207535T1 (de) * 1987-06-22 2001-11-15 Medeva Holdings Bv Hepatitis-b-oberflächenantigen enthaltendes peptid
AU619753B2 (en) * 1987-06-22 1992-02-06 Medeva Holdings B.V. Hepatitis b surface antigen vaccine
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
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AU3269793A (en) * 1991-12-27 1993-07-28 Gensci Limited Method for obtaining recombinant surface antigen of hepatitis B, antigen and vaccine based on it
PT835663E (pt) 1992-05-23 2010-01-04 Glaxosmithkline Biolog Sa Vacinas combinadas compreendendo o antigénio de superfície da hepatite b e outros antigénios
ES2143716T3 (es) 1992-06-25 2000-05-16 Smithkline Beecham Biolog Composicion de vacuna que contiene adyuvantes.
DK0672136T3 (da) * 1992-07-08 2000-08-21 Innogenetics Nv Polypeptider, der er afledt fra endonexin 2 og har hepatitis B virus-receptoraktivitet, og deres anvendelse i diagnostiske
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CN1059927C (zh) * 1994-03-10 2000-12-27 中国科学院上海生物化学研究所 羧端带有前表面抗原1抗原决定簇的乙肝表面抗原融合基因及其编码蛋白
US6100043A (en) * 1995-08-04 2000-08-08 The Perkin-Elmer Corporation Recombinant clone selection system
US5843656A (en) * 1995-08-07 1998-12-01 The Perkin-Elmer Corporation Recombinant clone selection system
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Also Published As

Publication number Publication date
CN86102640A (zh) 1987-04-08
ATE139795T1 (de) 1996-07-15
ES553953A0 (es) 1988-06-01
HK1003794A1 (en) 1998-11-06
IE75355B1 (en) 1997-08-27
EP0719863A1 (de) 1996-07-03
AP8600035A0 (en) 1987-10-14
JPS6255088A (ja) 1987-03-10
FI861417A0 (fi) 1986-04-01
EP0198474B1 (de) 1996-06-26
EP0198474A1 (de) 1986-10-22
DE3650536T2 (de) 1997-02-27
SG43220A1 (en) 1997-10-17
ZA862797B (en) 1988-04-27
IL78472A0 (en) 1986-08-31
ES8802440A1 (es) 1988-06-01
IL78472A (en) 2004-08-31
IE860965L (en) 1986-10-15
YU60986A (en) 1988-10-31

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