DE3521679A1 - Verfahren zum binden von igg an protein a - Google Patents
Verfahren zum binden von igg an protein aInfo
- Publication number
- DE3521679A1 DE3521679A1 DE19853521679 DE3521679A DE3521679A1 DE 3521679 A1 DE3521679 A1 DE 3521679A1 DE 19853521679 DE19853521679 DE 19853521679 DE 3521679 A DE3521679 A DE 3521679A DE 3521679 A1 DE3521679 A1 DE 3521679A1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- immunoglobulin
- molecules
- solution
- buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/828—Protein A
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/623,797 US4704366A (en) | 1984-06-22 | 1984-06-22 | Process for binding IgG to protein A |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3521679A1 true DE3521679A1 (de) | 1986-01-02 |
| DE3521679C2 DE3521679C2 (enExample) | 1989-08-24 |
Family
ID=24499435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19853521679 Granted DE3521679A1 (de) | 1984-06-22 | 1985-06-18 | Verfahren zum binden von igg an protein a |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4704366A (enExample) |
| JP (2) | JPS6112631A (enExample) |
| DE (1) | DE3521679A1 (enExample) |
| GB (1) | GB2160530B (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283323A (en) * | 1985-08-07 | 1994-02-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method of producing immune response |
| US4977247A (en) * | 1986-02-14 | 1990-12-11 | Genex Corporation | Immobilized protein G variants and the use thereof |
| SE459662B (sv) * | 1986-03-21 | 1989-07-24 | Pharmacia Ab | Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet |
| US5089605A (en) * | 1987-03-13 | 1992-02-18 | Repligen Corporation | Immobilized immunoglobulin-binding proteins |
| JPS6419024A (en) * | 1987-07-15 | 1989-01-23 | Tosoh Corp | Separation of immunoglobulin g subclass |
| US4981961A (en) * | 1988-09-12 | 1991-01-01 | Bioprobe International, Inc. | Synthetic affinity ligand compositions and methods for purification and recovery of organic molecules |
| US4933435A (en) * | 1989-04-05 | 1990-06-12 | Bioprobe International | Antibody purification process |
| US5151504A (en) * | 1989-11-17 | 1992-09-29 | E. R. Squibb & Sons, Inc. | Method for purification of monoclonal antibodies |
| US5077391A (en) * | 1989-12-01 | 1991-12-31 | Raison Robert L | Purification of immunoglobulin M |
| JPH03185000A (ja) * | 1989-12-15 | 1991-08-12 | Tosoh Corp | プロテインAと免疫グロブリンG(IgG)との結合方法 |
| US5200471A (en) * | 1990-11-05 | 1993-04-06 | Minnesota Mining And Manufacturing Company | Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same |
| US5245016A (en) * | 1991-01-31 | 1993-09-14 | University Of Utah Research Foundation | Pseudomonas maltophilia immunoglobulin binding protein and methods for its use |
| WO1994022918A1 (en) * | 1993-03-29 | 1994-10-13 | Minnesota Mining And Manufacturing Company | Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof |
| US5593822A (en) * | 1993-12-07 | 1997-01-14 | John Wayne Cancer Institute | IgG depleted serum preparations and methods for antibody production |
| US5561045A (en) * | 1994-01-04 | 1996-10-01 | Intracel Corporation | Detection reagent, article, and immunoassay method |
| JPH08511280A (ja) * | 1994-04-01 | 1996-11-26 | ユニシン・テクノロジーズ・インコーポレーテッド | 合成親和性リガンドを用いた免疫グロブリンの精製のための高塩濃度結合バッファー |
| US7285268B2 (en) * | 2002-11-26 | 2007-10-23 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| AU2003298783B2 (en) * | 2002-11-26 | 2010-11-04 | Abbvie Biotherapeutics Inc. | Chimeric and humanized antibodies to alpha5beta1 integrin that modulate angiogenesis |
| US7276589B2 (en) * | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| DK1755659T3 (da) * | 2004-03-24 | 2012-02-27 | Abbott Biotherapeutics Corp | Anvendelse af anti-alfa5beta1-antistoffer til inhibering af kræftcelleproliferation |
| AU2008282331A1 (en) * | 2007-07-27 | 2009-02-05 | Facet Biotech Corporation | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (CD49E) |
| US20100158893A1 (en) * | 2008-12-19 | 2010-06-24 | Baxter International Inc. | Systems and methods for obtaining immunoglobulin from blood |
| WO2011064910A1 (ja) * | 2009-11-25 | 2011-06-03 | パナソニック株式会社 | 免疫測定方法 |
| CA2784278C (en) | 2009-12-18 | 2019-02-26 | Novartis Ag | Wash solution and method for affinity chromatography |
| EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| CN104105965B (zh) | 2011-11-21 | 2016-07-06 | 爱贝斯股份有限公司 | 侧向流和相关免疫测定中的信号放大 |
| US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
| US9505833B2 (en) | 2012-04-20 | 2016-11-29 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| WO2013177115A2 (en) * | 2012-05-21 | 2013-11-28 | Abbvie Inc. | Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography |
| WO2013176754A1 (en) | 2012-05-24 | 2013-11-28 | Abbvie Inc. | Novel purification of antibodies using hydrophobic interaction chromatography |
| HK1211981A1 (en) | 2012-09-02 | 2016-06-03 | Abbvie Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
| WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| PT3331818T (pt) | 2015-08-04 | 2024-08-30 | Zoetis Services Llc | Amplificação de sinal em ensaios de parceiro de ligação específica plasmónicos à base de solução |
| CN109311949B (zh) | 2016-05-11 | 2022-09-16 | 思拓凡生物工艺研发有限公司 | 储存分离基质的方法 |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10513537B2 (en) | 2016-05-11 | 2019-12-24 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| WO2017194593A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| KR102486615B1 (ko) | 2017-01-30 | 2023-01-11 | 조에티스 서비시즈 엘엘씨 | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 |
| WO2019183334A1 (en) | 2018-03-21 | 2019-09-26 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960720A (en) * | 1973-03-23 | 1976-06-01 | Exploaterings Aktiebolaget T.B.F. | Gel product for separation purposes and method of using the product for hydrophobic salting out adsorption |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4430318A (en) * | 1978-11-29 | 1984-02-07 | The United States Of America As Represented By The Department Of Health And Human Services | Immunoassay utilizing 125 I Protein A |
| US4230685A (en) * | 1979-02-28 | 1980-10-28 | Northwestern University | Method of magnetic separation of cells and the like, and microspheres for use therein |
| AU570911B2 (en) * | 1981-11-06 | 1988-03-31 | Baylor College Of Medicine | Immunoadsorbent based on immobilized protein a and its use |
-
1984
- 1984-06-22 US US06/623,797 patent/US4704366A/en not_active Expired - Fee Related
-
1985
- 1985-06-17 GB GB08515261A patent/GB2160530B/en not_active Expired
- 1985-06-18 DE DE19853521679 patent/DE3521679A1/de active Granted
- 1985-06-21 JP JP60135808A patent/JPS6112631A/ja active Granted
-
1991
- 1991-04-15 JP JP3109760A patent/JPH04234899A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960720A (en) * | 1973-03-23 | 1976-06-01 | Exploaterings Aktiebolaget T.B.F. | Gel product for separation purposes and method of using the product for hydrophobic salting out adsorption |
Non-Patent Citations (18)
| Title |
|---|
| "Affinity Chromatography der Firma Parmacia Fine Chemicals (1979), S. 7, 16, 92 u. 93 |
| "Hybridoma Techniques", EMBO, SKMB Course 1980, Basel, S. 36 und 37 |
| "Protein Purification" von R.K. Scopes, Springer-Verlag New York(1982), S. 43-48 u. 139-140 |
| 2 Chromatogr. Synth. Biol. Polym.,S.337-340(1978) * |
| Biochemistry 20, S. 2361(1980) * |
| Biochemistry, Vol. 20, No. 9, 28. April 1981, S. 2361-2370 |
| Druckschrift IBF "Practical Guide for Use in * |
| Druckschrift IBF "Practical Guide for Use in Affinity Chromatograph and related techniques" 65-66, 138(1983) |
| Experimental Immunochemistry, 2. Aufl., S. 628-629, Charles C. Thomas, Hrsg.,(1961) |
| GODING, J.: "Monoclonal Antibodies: Principles and Practice"(1983), Academic Press, S. 197-198 * |
| HOPPE_SEYLER`S, Z.: Physiol. Chem. 359. S. 975, 984(1978) * |
| Immunological Communications ll, S. 189-200(1982 * |
| J. Imm- Meth. 64, S. 1-6(1983) * |
| LINDMARK, R.: Dissertation "Studies on Protein A from Staphylococcus Aureus", Uppsala 1981, Veröffentlichungen zur Dissertation: J.Immunol. Meth., 62, S. 1-13(1983) * |
| Produktinformation der Firma Pharmacia Fine Chemicals überOctyl-Sepharose CL-4B, Phenyl-Sepharose CL-4B aus dem Jahre 1979, S. 1-13 |
| SANDBERG, H. (Hrsg.): Proceedings of the International Workshop on Technology for Protein Separationand Improvement of Blood Plasma Fractionation, DHEW Publication No. (NIH) 78-1422(1978), S. 431 * |
| Scand. J. Immunol. 9(1979), S. 359-364 |
| Svensk Farmaceutisk Tidskrift, 86(10), S. 18-22(1982) * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2160530A (en) | 1985-12-24 |
| JPH0455440B2 (enExample) | 1992-09-03 |
| JPS6112631A (ja) | 1986-01-21 |
| GB8515261D0 (en) | 1985-07-17 |
| GB2160530B (en) | 1987-10-28 |
| DE3521679C2 (enExample) | 1989-08-24 |
| US4704366A (en) | 1987-11-03 |
| JPH04234899A (ja) | 1992-08-24 |
| JPH0543719B2 (enExample) | 1993-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8363 | Opposition against the patent | ||
| 8331 | Complete revocation |