DE3521679A1 - Verfahren zum binden von igg an protein a - Google Patents

Verfahren zum binden von igg an protein a

Info

Publication number
DE3521679A1
DE3521679A1 DE19853521679 DE3521679A DE3521679A1 DE 3521679 A1 DE3521679 A1 DE 3521679A1 DE 19853521679 DE19853521679 DE 19853521679 DE 3521679 A DE3521679 A DE 3521679A DE 3521679 A1 DE3521679 A1 DE 3521679A1
Authority
DE
Germany
Prior art keywords
protein
immunoglobulin
molecules
solution
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19853521679
Other languages
German (de)
English (en)
Other versions
DE3521679C2 (enExample
Inventor
Hector Larkspur Calif. Juarez-Salinas
Gary Steven Livermore Calif. Ott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24499435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3521679(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of DE3521679A1 publication Critical patent/DE3521679A1/de
Application granted granted Critical
Publication of DE3521679C2 publication Critical patent/DE3521679C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/828Protein A
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE19853521679 1984-06-22 1985-06-18 Verfahren zum binden von igg an protein a Granted DE3521679A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/623,797 US4704366A (en) 1984-06-22 1984-06-22 Process for binding IgG to protein A

Publications (2)

Publication Number Publication Date
DE3521679A1 true DE3521679A1 (de) 1986-01-02
DE3521679C2 DE3521679C2 (enExample) 1989-08-24

Family

ID=24499435

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853521679 Granted DE3521679A1 (de) 1984-06-22 1985-06-18 Verfahren zum binden von igg an protein a

Country Status (4)

Country Link
US (1) US4704366A (enExample)
JP (2) JPS6112631A (enExample)
DE (1) DE3521679A1 (enExample)
GB (1) GB2160530B (enExample)

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US5283323A (en) * 1985-08-07 1994-02-01 The United States Of America As Represented By The Department Of Health And Human Services Method of producing immune response
US4977247A (en) * 1986-02-14 1990-12-11 Genex Corporation Immobilized protein G variants and the use thereof
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
US5089605A (en) * 1987-03-13 1992-02-18 Repligen Corporation Immobilized immunoglobulin-binding proteins
JPS6419024A (en) * 1987-07-15 1989-01-23 Tosoh Corp Separation of immunoglobulin g subclass
US4981961A (en) * 1988-09-12 1991-01-01 Bioprobe International, Inc. Synthetic affinity ligand compositions and methods for purification and recovery of organic molecules
US4933435A (en) * 1989-04-05 1990-06-12 Bioprobe International Antibody purification process
US5151504A (en) * 1989-11-17 1992-09-29 E. R. Squibb & Sons, Inc. Method for purification of monoclonal antibodies
US5077391A (en) * 1989-12-01 1991-12-31 Raison Robert L Purification of immunoglobulin M
JPH03185000A (ja) * 1989-12-15 1991-08-12 Tosoh Corp プロテインAと免疫グロブリンG(IgG)との結合方法
US5200471A (en) * 1990-11-05 1993-04-06 Minnesota Mining And Manufacturing Company Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same
US5245016A (en) * 1991-01-31 1993-09-14 University Of Utah Research Foundation Pseudomonas maltophilia immunoglobulin binding protein and methods for its use
WO1994022918A1 (en) * 1993-03-29 1994-10-13 Minnesota Mining And Manufacturing Company Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof
US5593822A (en) * 1993-12-07 1997-01-14 John Wayne Cancer Institute IgG depleted serum preparations and methods for antibody production
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
JPH08511280A (ja) * 1994-04-01 1996-11-26 ユニシン・テクノロジーズ・インコーポレーテッド 合成親和性リガンドを用いた免疫グロブリンの精製のための高塩濃度結合バッファー
US7285268B2 (en) * 2002-11-26 2007-10-23 Pdl Biopharma, Inc. Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis
AU2003298783B2 (en) * 2002-11-26 2010-11-04 Abbvie Biotherapeutics Inc. Chimeric and humanized antibodies to alpha5beta1 integrin that modulate angiogenesis
US7276589B2 (en) * 2002-11-26 2007-10-02 Pdl Biopharma, Inc. Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis
DK1755659T3 (da) * 2004-03-24 2012-02-27 Abbott Biotherapeutics Corp Anvendelse af anti-alfa5beta1-antistoffer til inhibering af kræftcelleproliferation
AU2008282331A1 (en) * 2007-07-27 2009-02-05 Facet Biotech Corporation Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (CD49E)
US20100158893A1 (en) * 2008-12-19 2010-06-24 Baxter International Inc. Systems and methods for obtaining immunoglobulin from blood
WO2011064910A1 (ja) * 2009-11-25 2011-06-03 パナソニック株式会社 免疫測定方法
CA2784278C (en) 2009-12-18 2019-02-26 Novartis Ag Wash solution and method for affinity chromatography
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
CN104105965B (zh) 2011-11-21 2016-07-06 爱贝斯股份有限公司 侧向流和相关免疫测定中的信号放大
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
WO2013177115A2 (en) * 2012-05-21 2013-11-28 Abbvie Inc. Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
HK1211981A1 (en) 2012-09-02 2016-06-03 Abbvie Inc. Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
PT3331818T (pt) 2015-08-04 2024-08-30 Zoetis Services Llc Amplificação de sinal em ensaios de parceiro de ligação específica plasmónicos à base de solução
CN109311949B (zh) 2016-05-11 2022-09-16 思拓凡生物工艺研发有限公司 储存分离基质的方法
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
WO2017194593A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
KR102486615B1 (ko) 2017-01-30 2023-01-11 조에티스 서비시즈 엘엘씨 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960720A (en) * 1973-03-23 1976-06-01 Exploaterings Aktiebolaget T.B.F. Gel product for separation purposes and method of using the product for hydrophobic salting out adsorption

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430318A (en) * 1978-11-29 1984-02-07 The United States Of America As Represented By The Department Of Health And Human Services Immunoassay utilizing 125 I Protein A
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
AU570911B2 (en) * 1981-11-06 1988-03-31 Baylor College Of Medicine Immunoadsorbent based on immobilized protein a and its use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960720A (en) * 1973-03-23 1976-06-01 Exploaterings Aktiebolaget T.B.F. Gel product for separation purposes and method of using the product for hydrophobic salting out adsorption

Non-Patent Citations (18)

* Cited by examiner, † Cited by third party
Title
"Affinity Chromatography der Firma Parmacia Fine Chemicals (1979), S. 7, 16, 92 u. 93
"Hybridoma Techniques", EMBO, SKMB Course 1980, Basel, S. 36 und 37
"Protein Purification" von R.K. Scopes, Springer-Verlag New York(1982), S. 43-48 u. 139-140
2 Chromatogr. Synth. Biol. Polym.,S.337-340(1978) *
Biochemistry 20, S. 2361(1980) *
Biochemistry, Vol. 20, No. 9, 28. April 1981, S. 2361-2370
Druckschrift IBF "Practical Guide for Use in *
Druckschrift IBF "Practical Guide for Use in Affinity Chromatograph and related techniques" 65-66, 138(1983)
Experimental Immunochemistry, 2. Aufl., S. 628-629, Charles C. Thomas, Hrsg.,(1961)
GODING, J.: "Monoclonal Antibodies: Principles and Practice"(1983), Academic Press, S. 197-198 *
HOPPE_SEYLER`S, Z.: Physiol. Chem. 359. S. 975, 984(1978) *
Immunological Communications ll, S. 189-200(1982 *
J. Imm- Meth. 64, S. 1-6(1983) *
LINDMARK, R.: Dissertation "Studies on Protein A from Staphylococcus Aureus", Uppsala 1981, Veröffentlichungen zur Dissertation: J.Immunol. Meth., 62, S. 1-13(1983) *
Produktinformation der Firma Pharmacia Fine Chemicals überOctyl-Sepharose CL-4B, Phenyl-Sepharose CL-4B aus dem Jahre 1979, S. 1-13
SANDBERG, H. (Hrsg.): Proceedings of the International Workshop on Technology for Protein Separationand Improvement of Blood Plasma Fractionation, DHEW Publication No. (NIH) 78-1422(1978), S. 431 *
Scand. J. Immunol. 9(1979), S. 359-364
Svensk Farmaceutisk Tidskrift, 86(10), S. 18-22(1982) *

Also Published As

Publication number Publication date
GB2160530A (en) 1985-12-24
JPH0455440B2 (enExample) 1992-09-03
JPS6112631A (ja) 1986-01-21
GB8515261D0 (en) 1985-07-17
GB2160530B (en) 1987-10-28
DE3521679C2 (enExample) 1989-08-24
US4704366A (en) 1987-11-03
JPH04234899A (ja) 1992-08-24
JPH0543719B2 (enExample) 1993-07-02

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8363 Opposition against the patent
8331 Complete revocation