DE3501383A1 - Verfahren zur herstellung von n,n'-disubstituierten guanidinen - Google Patents

Verfahren zur herstellung von n,n'-disubstituierten guanidinen

Info

Publication number
DE3501383A1
DE3501383A1 DE19853501383 DE3501383A DE3501383A1 DE 3501383 A1 DE3501383 A1 DE 3501383A1 DE 19853501383 DE19853501383 DE 19853501383 DE 3501383 A DE3501383 A DE 3501383A DE 3501383 A1 DE3501383 A1 DE 3501383A1
Authority
DE
Germany
Prior art keywords
ammonia
oxygen
reaction
radical
a3gw321o8
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19853501383
Other languages
German (de)
English (en)
Other versions
DE3501383C2 (enExample
Inventor
Manfred Dipl.-Chem. Dr. 8765 Mechenhard Bergfeld
Ludwig Dipl.-Chem. Dr. 8753 Obernburg Eisenhuth
Hans Dipl.-Ing. Dr. 8751 Kleinwallstadt Zengel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Patente 5600 Wuppertal De GmbH
Original Assignee
Akzo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo GmbH filed Critical Akzo GmbH
Priority to DE19853501383 priority Critical patent/DE3501383A1/de
Priority to US06/819,881 priority patent/US4898978A/en
Publication of DE3501383A1 publication Critical patent/DE3501383A1/de
Application granted granted Critical
Publication of DE3501383C2 publication Critical patent/DE3501383C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19853501383 1985-01-17 1985-01-17 Verfahren zur herstellung von n,n'-disubstituierten guanidinen Granted DE3501383A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19853501383 DE3501383A1 (de) 1985-01-17 1985-01-17 Verfahren zur herstellung von n,n'-disubstituierten guanidinen
US06/819,881 US4898978A (en) 1985-01-17 1986-01-17 Process for the preparation of N,N'-disubstituted guanidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853501383 DE3501383A1 (de) 1985-01-17 1985-01-17 Verfahren zur herstellung von n,n'-disubstituierten guanidinen

Publications (2)

Publication Number Publication Date
DE3501383A1 true DE3501383A1 (de) 1986-07-17
DE3501383C2 DE3501383C2 (enExample) 1990-02-22

Family

ID=6260050

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853501383 Granted DE3501383A1 (de) 1985-01-17 1985-01-17 Verfahren zur herstellung von n,n'-disubstituierten guanidinen

Country Status (2)

Country Link
US (1) US4898978A (enExample)
DE (1) DE3501383A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5385946A (en) * 1986-07-10 1995-01-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Method for treating hypertension with disubstituted granidine compounds
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5336689A (en) * 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
ZA911553B (en) 1990-03-02 1991-12-24 Oregon State Tri-and tetra-substituted guanidines and their use as excitatory amino acid and antagonists
EP0532642A1 (en) * 1990-05-25 1993-03-24 STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON Substituted guanidines having high binding to the sigma receptor and the use thereof
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
EP0940139B1 (en) * 1991-02-08 2005-02-02 Scion Pharmaceuticals, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
EP0705100B1 (en) * 1993-05-27 2003-07-30 CeNes Limited Therapeutic substituted guanidines
KR100424523B1 (ko) * 1993-11-23 2004-09-30 캠브리지 뉴로사이언스, 인코포레이티드 치료용의치환된구아니딘
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
KR100423272B1 (ko) 1994-02-03 2004-09-01 캠브리지 뉴로사이언스, 인코포레이티드 신경전달물질의방출을조절하는화합물,이의약학적으로허용가능한염및이를포함하는약학조성물
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
WO2010048164A2 (en) * 2008-10-20 2010-04-29 University Of South Florida N,n'-di-p-bromophenyl guanidine treatment for stroke at delayed timepoints
CN102363601A (zh) * 2011-09-20 2012-02-29 科迈化工股份有限公司 以双氧水为氧化剂生产橡胶促进剂dgp的方法
CN102363602A (zh) * 2011-09-20 2012-02-29 科迈化工股份有限公司 以双氧水为氧化剂生产硫化促进剂dpg的方法
CN105348149A (zh) * 2015-12-15 2016-02-24 山东尚舜化工有限公司 一种提高二苯胍产品质量的方法
CN106810469B (zh) * 2017-02-24 2019-09-24 山东尚舜化工有限公司 一种连续生产橡胶硫化促进剂二苯胍的装置及其生产方法
CN108727228A (zh) * 2017-10-23 2018-11-02 科迈化工股份有限公司 一种硫化促进剂二苯胍（dpg）的连续生产工艺
CN110407720B (zh) * 2019-08-20 2021-07-27 西安近代化学研究所 一种碘催化硫脲脱硫制备取代胍的合成方法
US20240117149A1 (en) 2022-09-28 2024-04-11 The Goodyear Tire & Rubber Company Rubber - forming additives from end of life tires through syngas production
US20240124683A1 (en) 2022-09-28 2024-04-18 The Goodyear Tire & Rubber Company Rubber - forming additives from biomass through syngas production
US20250163236A1 (en) 2023-11-21 2025-05-22 The Goodyear Tire & Rubber Company Production of rubber compositions from end of life tires
CN119528982A (zh) * 2024-11-22 2025-02-28 沈阳工业大学 一种大分子硫磷复合原油蒸馏装置高温缓蚀剂其制备方法及用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE418100C (de) * 1922-06-19 1925-08-29 Naugatuck Chemical Company Verfahren zur Darstellung von Diarylguanidinen
DE481994C (de) * 1926-08-27 1929-09-04 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Diarylguanidinen
DE630966C (de) * 1933-10-13 1936-06-16 Silesia Ver Chemischer Fabrike Verfahren zur Herstellung von Diarylguanidinen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1630769A (en) * 1923-02-15 1927-05-31 Du Pont Process of making disubstituted guanidines
DE418994C (de) * 1924-08-02 1925-09-24 Rudolf Horn Verfahren zur Ausfuehrung von Mehrfarbendruck auf Bogen in einem Arbeitsgange mittels eines Gummizylinders
GB303044A (en) * 1927-09-26 1928-12-27 Ig Farbenindustrie Ag Process for the manufacture of substituted guanidines
DE2716897C3 (de) * 1977-04-16 1980-01-03 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von N,N'-Diphenylthioharnstoffen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE418100C (de) * 1922-06-19 1925-08-29 Naugatuck Chemical Company Verfahren zur Darstellung von Diarylguanidinen
DE481994C (de) * 1926-08-27 1929-09-04 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Diarylguanidinen
DE630966C (de) * 1933-10-13 1936-06-16 Silesia Ver Chemischer Fabrike Verfahren zur Herstellung von Diarylguanidinen
DE632130C (de) * 1933-10-13 1936-07-04 Silesia Ver Chemischer Fabrike Verfahren zur Herstellung von Diarylguanidinen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CH-Jahrbuch: W.Theilheimer: Synthetic Methods, Bd.25, 1971, Nr.323 *
SU-PS 168 683, referiert in US-Z.: Chem. Abstr. Vol.63, 1965, Sp.1734c *
US-Z: Chemical Abstracts, Vol.92, 1980, Ref.Nr. 94093 g *
US-Z: Chemical Abstracts, Vol.99, 1983, Ref.Nr. 212248 f *

Also Published As

Publication number Publication date
US4898978A (en) 1990-02-06
DE3501383C2 (enExample) 1990-02-22

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Legal Events

Date Code Title Description
OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
8110 Request for examination paragraph 44
8127 New person/name/address of the applicant

Owner name: AKZO PATENTE GMBH, 5600 WUPPERTAL, DE

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee