DE3490749C2 - 11-Desoxy-17alpha-hydroxycorticosteronester - Google Patents

11-Desoxy-17alpha-hydroxycorticosteronester

Info

Publication number
DE3490749C2
DE3490749C2 DE19843490749 DE3490749A DE3490749C2 DE 3490749 C2 DE3490749 C2 DE 3490749C2 DE 19843490749 DE19843490749 DE 19843490749 DE 3490749 A DE3490749 A DE 3490749A DE 3490749 C2 DE3490749 C2 DE 3490749C2
Authority
DE
Germany
Prior art keywords
deoxy
chloroethyl
tumors
hydroxycorticosterone
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19843490749
Other languages
German (de)
English (en)
Other versions
DE3490749T1 (de
Inventor
Kurdjumova Nikolaevna
Skodinskaya Nikolaevna
Susinina Pavlovna
Yaguzinskaya Petrovna
Lagova Dmitrievna
Sofiina Petrovna
Valueva Michailovna
Lopatin Vyaceslavovic
Krasnova Andreevna
Syrkin Borisovic
Michailova Michailovna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
V ONKOLOGICESKIJ NAUCNYJ CENTR
Original Assignee
V ONKOLOGICESKIJ NAUCNYJ CENTR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by V ONKOLOGICESKIJ NAUCNYJ CENTR filed Critical V ONKOLOGICESKIJ NAUCNYJ CENTR
Application granted granted Critical
Publication of DE3490749C2 publication Critical patent/DE3490749C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19843490749 1984-07-31 1984-07-31 11-Desoxy-17alpha-hydroxycorticosteronester Expired DE3490749C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1984/000043 WO1986000908A1 (fr) 1984-07-31 1984-07-31 DERIVES DE 11-DESOXY-17alpha-OXYCORTICOSTERONE

Publications (1)

Publication Number Publication Date
DE3490749C2 true DE3490749C2 (de) 1989-12-28

Family

ID=21616860

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19843490749 Expired DE3490749C2 (de) 1984-07-31 1984-07-31 11-Desoxy-17alpha-hydroxycorticosteronester
DE19843490749 Pending DE3490749T1 (de) 1984-07-31 1984-07-31 Derivate von ll-Desoxy-17α-oxykortikosteron

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19843490749 Pending DE3490749T1 (de) 1984-07-31 1984-07-31 Derivate von ll-Desoxy-17α-oxykortikosteron

Country Status (8)

Country Link
US (1) US4810701A (enExample)
JP (1) JPH01500111A (enExample)
CH (1) CH666044A5 (enExample)
DE (2) DE3490749C2 (enExample)
FI (1) FI80048C (enExample)
GB (1) GB2176189B (enExample)
SE (1) SE448166B (enExample)
WO (1) WO1986000908A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP141A (en) * 1990-04-25 1991-08-25 Richter Gedeon Vegyeszet Novel steroid doils.

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933332A (en) * 1986-03-21 1990-06-12 Kurdjumova Kira N 11-desoxy-17-α-hydroxycorticosterone derivatives
US5483697A (en) * 1989-05-22 1996-01-16 Board Of Regents The University Of Texas Multilayer protective coverings with a sealing solution
AU1773892A (en) * 1991-04-09 1992-11-17 Upjohn Company, The Use of amines to sensitize multidrug-resistant cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2001305B2 (de) * 1969-01-23 1974-08-15 Ab Leo, Haelsingborg (Schweden) Cytostatisch wirksame Corticosteroid-21-ester, deren Herstellung sowie diese enthaltende Arzneimittel
DE2702509A1 (de) * 1976-01-22 1977-07-28 Leo Ab 17alpha-ester von gestagenen mit antitumor-wirksamkeit, deren herstellung und diese ester enthaltende mittel
DE2932607C2 (de) * 1978-08-14 1982-07-29 Kureha Kagaku Kogyo K.K., Tokyo Chlorambucilderivate, Verfahren zur Herstellung derselben und Antitumormittel mit einem Gehalt derselben

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793461A1 (de) * 1968-09-20 1971-07-01 Hoechst Ag 21-(Cyclobutyl-carbonsaeure)-ester von Steroidderivaten und Verfahren zu ihrer Herstellung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2001305B2 (de) * 1969-01-23 1974-08-15 Ab Leo, Haelsingborg (Schweden) Cytostatisch wirksame Corticosteroid-21-ester, deren Herstellung sowie diese enthaltende Arzneimittel
DE2702509A1 (de) * 1976-01-22 1977-07-28 Leo Ab 17alpha-ester von gestagenen mit antitumor-wirksamkeit, deren herstellung und diese ester enthaltende mittel
DE2932607C2 (de) * 1978-08-14 1982-07-29 Kureha Kagaku Kogyo K.K., Tokyo Chlorambucilderivate, Verfahren zur Herstellung derselben und Antitumormittel mit einem Gehalt derselben

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
The Merck Index, 10. Aufl. 1983, S.7612-13 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP141A (en) * 1990-04-25 1991-08-25 Richter Gedeon Vegyeszet Novel steroid doils.

Also Published As

Publication number Publication date
SE448166B (sv) 1987-01-26
WO1986000908A1 (fr) 1986-02-13
FI80048C (fi) 1990-04-10
FI861325L (fi) 1986-03-26
FI80048B (fi) 1989-12-29
JPH0124160B2 (enExample) 1989-05-10
CH666044A5 (de) 1988-06-30
DE3490749T1 (de) 1986-08-07
SE8601344D0 (sv) 1986-03-21
US4810701A (en) 1989-03-07
GB2176189B (en) 1988-03-02
GB8606415D0 (en) 1986-04-23
SE8601344L (sv) 1986-03-21
GB2176189A (en) 1986-12-17
JPH01500111A (ja) 1989-01-19
FI861325A0 (fi) 1986-03-26

Similar Documents

Publication Publication Date Title
EP0000742B1 (de) Corticoid-17-Alkylcarbonate und Verfahren zu deren Herstellung und diese enthaltende Mittel
DE4025342A1 (de) In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel
EP1132395A2 (de) Verfahren zur Herstellung eines pharmazeutisch aktiven Peptides
DE3490749C2 (de) 11-Desoxy-17alpha-hydroxycorticosteronester
DE2154245B2 (de) 3-Hydrazino-6-(2-hydroxypropylamino)-pyridazinderivate, Verfahren zu ihrer Herstellung und sie enthaltendes pharmazeutisches Präparat
EP0072531A1 (de) Neue Cyclophosphamid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE3336292C2 (enExample)
DE2735455C3 (de) Daunomycinanaloga, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2817923C2 (de) Septacidinverbindungen und diese enthaltende Arzneimittel
DE1468893C3 (de) Verfahren zur Herstellung von 21 -Dicyclohexylmethylcarbonaten von Corticostefoiden und einige dieser Verbindungen
DE2404120B2 (de) Leurosinderivate, ihre salze, verfahren zu ihrer herstellung und pharmazeutische mittel
DE1807585C3 (de) 14,15beta-Epoxycardenolide, Verfahren zu deren Herstellung und diese enthaltende Mittel
DE2410201B2 (de) 6-substituierte 3-carbaethoxyhydrazinopyridazine beziehungsweise ihre salze sowie solche enthaltende arzneimittel und verfahren zur herstellung derselben
EP0030331B1 (de) Neue C-3-verzweigte Cardenolid-glykoside, ihre Herstellung und Verwendung
DE1793694C3 (de) Helveticosidderivate
CH628067A5 (de) Verfahren zur herstellung neuer 21-acetale von steroid-21-aldehyden.
DE1921462C3 (de) Steroid oxazoline, Verfahren zu deren Herstellung und dieselben ent haltende Arzneimittel
DE2109305B2 (de) 20-Hydroxylierte 17 a - MethyI-19-nor-pregna-4,9diene, Verfahren zu deren Herstellung sowie Zwischenprodukte
DE2560038C2 (de) H2-Chloräthyl)-1 nitroso-3-(hydroxycyclohexyl)harnstoffe, dieselben enthaltende Arzneimittel und Verfahren zur Herstellung der ersteren
DE1668079C3 (de) Dialkylorthocarbonate von 17alpha, 21-Dihydroxysteroiden und Verfahren zu ihrer Herstellung
DE2118995A1 (de) Neue oestrogen hochwirksame Steroide und ein Verfahren zu deren Herstellung
DE1468681C3 (de) 17beta-Tetrahydropyranyloxy verbindungen der Androstanreihe sowie Verfahren zu ihrer Herstellung und Heilmittel
EP0127000B1 (de) 1,3-bis(Dimethylamino)-2-propyl-4-chlorphenoxyacetat, seine Säureadditionssalze, Verfahren zu seiner Herstellung und diese Verbindungen enthaltende Arzneimittelpräparate
WO2023118484A1 (de) Epoxysteroide
EP0080675A1 (de) Neue Ketale von 3'''-Dehydro-cardenolid-tridigitoxosiden, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel