FI80048C - Foerfarande foer framstaellning av nya hormoncytostater 11-desoxi-17 -hydroxi-21-/p-di(2-kloretyl) aminofenylacetat/ och butyratkortikosteroner. - Google Patents

Foerfarande foer framstaellning av nya hormoncytostater 11-desoxi-17 -hydroxi-21-/p-di(2-kloretyl) aminofenylacetat/ och butyratkortikosteroner. Download PDF

Info

Publication number
FI80048C
FI80048C FI861325A FI861325A FI80048C FI 80048 C FI80048 C FI 80048C FI 861325 A FI861325 A FI 861325A FI 861325 A FI861325 A FI 861325A FI 80048 C FI80048 C FI 80048C
Authority
FI
Finland
Prior art keywords
deoxy
chloroethyl
hydroxy
corticosterone
compounds
Prior art date
Application number
FI861325A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI861325L (fi
FI80048B (fi
FI861325A0 (fi
Inventor
Kira Nikolaevna Kurdjumova
Elizaveta Nikolae Shkodinskaya
Ljudmila Pavlovna Sushinina
Valentina Petrov Yaguzhinskaya
Nina Dmitrievna Lagova
Zoya Petrovna Sofiina
Irina Mikhailovna Valueva
Petr Vyacheslavovich Lopatin
Margarita Andreevna Krasnova
Anatoly Borisovich Syrkin
Ljudmila Mikhailovn Mikhailova
Original Assignee
Onkolog Nts Ak Med V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onkolog Nts Ak Med V filed Critical Onkolog Nts Ak Med V
Publication of FI861325L publication Critical patent/FI861325L/fi
Publication of FI861325A0 publication Critical patent/FI861325A0/fi
Application granted granted Critical
Publication of FI80048B publication Critical patent/FI80048B/fi
Publication of FI80048C publication Critical patent/FI80048C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI861325A 1984-07-31 1986-03-26 Foerfarande foer framstaellning av nya hormoncytostater 11-desoxi-17 -hydroxi-21-/p-di(2-kloretyl) aminofenylacetat/ och butyratkortikosteroner. FI80048C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SU8400043 1984-07-31
PCT/SU1984/000043 WO1986000908A1 (fr) 1984-07-31 1984-07-31 DERIVES DE 11-DESOXY-17alpha-OXYCORTICOSTERONE

Publications (4)

Publication Number Publication Date
FI861325L FI861325L (fi) 1986-03-26
FI861325A0 FI861325A0 (fi) 1986-03-26
FI80048B FI80048B (fi) 1989-12-29
FI80048C true FI80048C (fi) 1990-04-10

Family

ID=21616860

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861325A FI80048C (fi) 1984-07-31 1986-03-26 Foerfarande foer framstaellning av nya hormoncytostater 11-desoxi-17 -hydroxi-21-/p-di(2-kloretyl) aminofenylacetat/ och butyratkortikosteroner.

Country Status (8)

Country Link
US (1) US4810701A (enExample)
JP (1) JPH01500111A (enExample)
CH (1) CH666044A5 (enExample)
DE (2) DE3490749C2 (enExample)
FI (1) FI80048C (enExample)
GB (1) GB2176189B (enExample)
SE (1) SE448166B (enExample)
WO (1) WO1986000908A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933332A (en) * 1986-03-21 1990-06-12 Kurdjumova Kira N 11-desoxy-17-α-hydroxycorticosterone derivatives
US5483697A (en) * 1989-05-22 1996-01-16 Board Of Regents The University Of Texas Multilayer protective coverings with a sealing solution
AP141A (en) * 1990-04-25 1991-08-25 Richter Gedeon Vegyeszet Novel steroid doils.
AU1773892A (en) * 1991-04-09 1992-11-17 Upjohn Company, The Use of amines to sensitize multidrug-resistant cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793461A1 (de) * 1968-09-20 1971-07-01 Hoechst Ag 21-(Cyclobutyl-carbonsaeure)-ester von Steroidderivaten und Verfahren zu ihrer Herstellung
GB1272841A (en) * 1969-01-23 1972-05-03 Leo Ab New corticoid steroid compounds of cytostatic interest
GB1558472A (en) * 1976-01-22 1980-01-03 Leo Ab 17-esters of 17- hydroxy gestogens
US4261910A (en) * 1978-08-14 1981-04-14 Kureha Kagaku Kogyo Kabushiki Kaisha Process for the preparation of Chlorambucil derivatives

Also Published As

Publication number Publication date
SE448166B (sv) 1987-01-26
WO1986000908A1 (fr) 1986-02-13
FI861325L (fi) 1986-03-26
FI80048B (fi) 1989-12-29
JPH0124160B2 (enExample) 1989-05-10
CH666044A5 (de) 1988-06-30
DE3490749T1 (de) 1986-08-07
SE8601344D0 (sv) 1986-03-21
DE3490749C2 (de) 1989-12-28
US4810701A (en) 1989-03-07
GB2176189B (en) 1988-03-02
GB8606415D0 (en) 1986-04-23
SE8601344L (sv) 1986-03-21
GB2176189A (en) 1986-12-17
JPH01500111A (ja) 1989-01-19
FI861325A0 (fi) 1986-03-26

Similar Documents

Publication Publication Date Title
Shashoua et al. . gamma.-Aminobutyric acid esters. I. Synthesis, brain uptake, and pharmacological studies of aliphatic and steroid esters of. gamma.-aminobutyric acid
CZ113594A3 (en) Tetrazole derivatives of bile acids, process of their preparation and use of said compounds as medicaments
US4304726A (en) Process for the preparation of cholesterol derivatives
CN1253563A (zh) 类皮质激素化合物的硝酸酯及其药物应用
EP0384842B1 (fr) Nouveaux 19-nor stéroides ayant en position 11béta une chaîne carbonée comportant une fonction amide ou carbamate, leur procédé de préparation et les intermédiaires de ce procédé, leur application comme médicaments et les compositions pharmaceutiques les renfermant
Sood et al. Boron analogues of amino acids VI. Synthesis and characterization of di-and tripeptide analogues as antineoplastic, anti-inflammatory and hypolipidemic agents
LV12207B (lv) Tricikliski savienojumi
IE921148A1 (en) Anti-tumor and anti-psoriatic agents
FI80048C (fi) Foerfarande foer framstaellning av nya hormoncytostater 11-desoxi-17 -hydroxi-21-/p-di(2-kloretyl) aminofenylacetat/ och butyratkortikosteroner.
SU797585A3 (ru) Способ получени сложных эфиров геста-гЕНОВ
EP0056000B1 (fr) Dérivés 17/(alkoxycarbonyle) (formamido) méthylène/stéroides et leur préparation
FI57114B (fi) Foerfarande foer framstaellning av nya vid cancerterapi anvaendbara terapeutiskt vaerdefulla enolestrar av steroider
WO1993006124A1 (de) 11β-SUBSTITUIERTE 14,17-ETHANOESTRATRIENE, VERFAHREN ZUR HERSTELLUNG DIESER VERBINDUNGEN, SOWIE IHRE VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN
Foster et al. Synthesis of steroidal cyclophosphamides
Mitoma et al. Metabolic disposition of chlorambucil in rats
US3749704A (en) N-(omega-amino lower alkyl)-amides of 1,17-modified acth peptides
Anastasiou et al. On the formation of homo‐azasteroidal esters of N, N‐bis (2‐chloroethyl) aminobenzoic acid isomers and their antitumor activity
CN1802383A (zh) 秋水仙碱苷类似物
US4933332A (en) 11-desoxy-17-α-hydroxycorticosterone derivatives
Mappus et al. Synthesis and stereochemistry of C-3-and C-7-linked (O-carboxymethyl)-oximino-and hemisuccinamido derivatives of 5α-dihydrotestosterone
SHIMADA et al. Syntheses of Bufotoxin Analogs
HU179949B (en) Process for preparing nitroso-carbamide derivatives
JPS58116459A (ja) トリヒドロキシビタミンd↓3化合物
FI84834B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara steroidderivat av androstanserien.
JPS6277372A (ja) ジロリン、その製造法およびそれを含有する薬学的組成物

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: VSESOJUZNY ONKOLOGICHESKY NAUCHNY TSENTR