DE3403922A1 - Mitomycin-analoge verbindungen - Google Patents
Mitomycin-analoge verbindungenInfo
- Publication number
- DE3403922A1 DE3403922A1 DE19843403922 DE3403922A DE3403922A1 DE 3403922 A1 DE3403922 A1 DE 3403922A1 DE 19843403922 DE19843403922 DE 19843403922 DE 3403922 A DE3403922 A DE 3403922A DE 3403922 A1 DE3403922 A1 DE 3403922A1
- Authority
- DE
- Germany
- Prior art keywords
- methoxy
- methyl
- hexahydro
- azirino
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46461283A | 1983-02-07 | 1983-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3403922A1 true DE3403922A1 (de) | 1984-08-09 |
Family
ID=23844605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19843403922 Withdrawn DE3403922A1 (de) | 1983-02-07 | 1984-02-04 | Mitomycin-analoge verbindungen |
Country Status (29)
Country | Link |
---|---|
JP (1) | JPS59152384A (da) |
KR (1) | KR900006854B1 (da) |
AT (1) | AT385509B (da) |
AU (1) | AU571193B2 (da) |
BE (1) | BE898856A (da) |
CA (1) | CA1252789A (da) |
CH (1) | CH658658A5 (da) |
DD (1) | DD233844A5 (da) |
DE (1) | DE3403922A1 (da) |
DK (1) | DK161890C (da) |
ES (1) | ES8607305A1 (da) |
FI (1) | FI80698C (da) |
FR (1) | FR2540500B1 (da) |
GB (1) | GB2134514B (da) |
GR (1) | GR81455B (da) |
HU (1) | HU190236B (da) |
IE (1) | IE56814B1 (da) |
IL (1) | IL70897A (da) |
IT (1) | IT1178855B (da) |
LU (1) | LU85199A1 (da) |
NL (1) | NL8400338A (da) |
NO (1) | NO161374C (da) |
NZ (1) | NZ206932A (da) |
OA (1) | OA07654A (da) |
PH (1) | PH20249A (da) |
PT (1) | PT78067B (da) |
SE (1) | SE461982B (da) |
YU (1) | YU44984B (da) |
ZA (1) | ZA84788B (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
CA1282069C (en) * | 1985-09-12 | 1991-03-26 | Damon L. Meyer | Antibody complexes of hapten-modified diagnostic or therapeutic agents |
JPS63150282A (ja) * | 1986-12-13 | 1988-06-22 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
JPS63246379A (ja) * | 1987-03-31 | 1988-10-13 | Kyowa Hakko Kogyo Co Ltd | 7−n,8−n−エチレンマイトマイシン8−イミン類 |
EP0485904B1 (en) * | 1990-11-13 | 1997-08-20 | Kyowa Hakko Kogyo Co., Ltd. | Mitomycin derivatives |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3332944A (en) * | 1964-11-02 | 1967-07-25 | American Cyanamid Co | Antibiotic derivatives of mitomycins a, b, c and porfiromycin |
US4268676A (en) * | 1979-12-05 | 1981-05-19 | University Patents, Inc. | Mitomycin analogs |
DE3217769A1 (de) * | 1981-05-15 | 1982-12-09 | University Patents, Inc., 6851 Norwalk, Conn. | Mitomycon-analoge verbindungen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5439098A (en) * | 1977-08-31 | 1979-03-24 | Kyowa Hakko Kogyo Co Ltd | Mitomycin c derivatives |
JPS5686184A (en) * | 1979-12-17 | 1981-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel mitomycin c derivative |
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
US4642352A (en) * | 1983-12-23 | 1987-02-10 | Bristol-Myers Company | Acylamino mitosanes |
-
1984
- 1984-01-25 NZ NZ206932A patent/NZ206932A/en unknown
- 1984-01-27 GB GB08402233A patent/GB2134514B/en not_active Expired
- 1984-02-02 ZA ZA84788A patent/ZA84788B/xx unknown
- 1984-02-03 AU AU24073/84A patent/AU571193B2/en not_active Ceased
- 1984-02-03 NL NL8400338A patent/NL8400338A/nl not_active Application Discontinuation
- 1984-02-04 DE DE19843403922 patent/DE3403922A1/de not_active Withdrawn
- 1984-02-06 ES ES529478A patent/ES8607305A1/es not_active Expired
- 1984-02-06 AT AT0037684A patent/AT385509B/de not_active IP Right Cessation
- 1984-02-06 CA CA000446811A patent/CA1252789A/en not_active Expired
- 1984-02-06 PH PH30204A patent/PH20249A/en unknown
- 1984-02-06 CH CH550/84A patent/CH658658A5/de not_active IP Right Cessation
- 1984-02-06 GR GR73720A patent/GR81455B/el unknown
- 1984-02-06 DK DK052484A patent/DK161890C/da active
- 1984-02-06 HU HU84483A patent/HU190236B/hu not_active IP Right Cessation
- 1984-02-06 IE IE272/84A patent/IE56814B1/en not_active IP Right Cessation
- 1984-02-06 NO NO840433A patent/NO161374C/no unknown
- 1984-02-06 PT PT78067A patent/PT78067B/pt not_active IP Right Cessation
- 1984-02-06 DD DD84259885A patent/DD233844A5/de not_active IP Right Cessation
- 1984-02-07 BE BE0/212351A patent/BE898856A/fr not_active IP Right Cessation
- 1984-02-07 KR KR1019840000574A patent/KR900006854B1/ko not_active IP Right Cessation
- 1984-02-07 SE SE8400628A patent/SE461982B/sv not_active IP Right Cessation
- 1984-02-07 LU LU85199A patent/LU85199A1/fr unknown
- 1984-02-07 YU YU217/84A patent/YU44984B/xx unknown
- 1984-02-07 FR FR8401845A patent/FR2540500B1/fr not_active Expired
- 1984-02-07 OA OA58227A patent/OA07654A/xx unknown
- 1984-02-07 FI FI840502A patent/FI80698C/fi not_active IP Right Cessation
- 1984-02-07 IT IT67113/84A patent/IT1178855B/it active
- 1984-02-07 IL IL70897A patent/IL70897A/xx unknown
- 1984-02-07 JP JP59021505A patent/JPS59152384A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3332944A (en) * | 1964-11-02 | 1967-07-25 | American Cyanamid Co | Antibiotic derivatives of mitomycins a, b, c and porfiromycin |
US4268676A (en) * | 1979-12-05 | 1981-05-19 | University Patents, Inc. | Mitomycin analogs |
DE3217769A1 (de) * | 1981-05-15 | 1982-12-09 | University Patents, Inc., 6851 Norwalk, Conn. | Mitomycon-analoge verbindungen |
Non-Patent Citations (2)
Title |
---|
Gann 71(1980), 560-562 * |
J. Meed. Chem. 26(1), 1983, 16-20 * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69523462T2 (de) | Substituierte o6-benzylguanine | |
DE69202243T2 (de) | 2,4-Diaminochinazolin-Derivate, um die Antitumorwirkung zu erhöhen. | |
DE69329574T2 (de) | Pharmazeutisch wirksame bicyclisch heterocyclische amine | |
DE69603240T2 (de) | Neue deazapurinderivate; eine neue klasse von crf1-spezifischen liganden | |
DE3712735A1 (de) | Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel | |
EP2104675A1 (de) | Substituierte 5h-pyrimidol[5,4-b]indole, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von nicht-soliden malignen tumoren des blutbildenden systems | |
DE68925270T2 (de) | Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidinderivate und diese enthaltende Arzneimittel | |
EP1296986B1 (de) | 5-aminoalkyl-pyrazolo[4,3-d]pyrimidine mit phosphodiesterase v inhibierender wirkung | |
EP0313630B1 (de) | Substituierte 2-acylpyridin-alpha-(n)-hetarylhydrazone sowie diese enthaltende arzneimittel | |
DE3446371A1 (de) | 5-pyrimidincarboxamide und 5-pyrimidinthiocarboxamide und ihre verwendung zur behandlung von leukaemie und tumoren | |
DE3403922A1 (de) | Mitomycin-analoge verbindungen | |
DE3217769A1 (de) | Mitomycon-analoge verbindungen | |
DE9290039U1 (de) | Pyrimidinderivate zur Verbesserung der Anti-Tumor-Aktivität | |
EP0180115A2 (de) | 1,2,4-Triazolo-carbamate und ihre Säureadditionssalze, Verfahren zu ihrer Herstellung und Arzneimittel | |
US4746746A (en) | Mitomycin analogs | |
EP0314984B1 (de) | Verwendung von 2-Pyrimidinyl-1-piperazin-Derivaten | |
DE3618724A1 (de) | N-(3-(nitro)-chinol-4-yl)-carboxamidinamide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel | |
DE69909592T4 (de) | Verwendung von thiadiazolo[4,3-a]pyridine derivaten | |
SU1272993A3 (ru) | Способ получени митомициновых производных | |
EP0194571B1 (de) | Heterocyclische Disulfide, Verfahren zu ihrer Herstellung und pharmazeutische Mittel, die diese Verbindungen enthalten | |
EP3805225A1 (en) | SELECTIVE A2a RECEPTOR ANTAGONIST | |
DE68911951T2 (de) | 5-(Substituierte Amino)-8-(phenyl oder substituierte phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one. | |
US4338441A (en) | Triazinones | |
AT313277B (de) | Verfahren zur Herstellung neuen Triazole | |
EP0711275B1 (de) | (thio)carbamidinsäure-derivate und diese enthaltende arzneimittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
8130 | Withdrawal |