FI80698C - Foerfarande foer framstaellning av terapeutiskt anvaendbara derivat av mitomycin a. - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara derivat av mitomycin a. Download PDF

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Publication number
FI80698C
FI80698C FI840502A FI840502A FI80698C FI 80698 C FI80698 C FI 80698C FI 840502 A FI840502 A FI 840502A FI 840502 A FI840502 A FI 840502A FI 80698 C FI80698 C FI 80698C
Authority
FI
Finland
Prior art keywords
mitomycin
methoxy
methyl
hexahydro
indole
Prior art date
Application number
FI840502A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI840502A0 (fi
FI840502A (fi
FI80698B (fi
Inventor
William A Remers
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of FI840502A0 publication Critical patent/FI840502A0/fi
Publication of FI840502A publication Critical patent/FI840502A/fi
Application granted granted Critical
Publication of FI80698B publication Critical patent/FI80698B/fi
Publication of FI80698C publication Critical patent/FI80698C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI840502A 1983-02-07 1984-02-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara derivat av mitomycin a. FI80698C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46461283A 1983-02-07 1983-02-07
US46461283 1983-02-07

Publications (4)

Publication Number Publication Date
FI840502A0 FI840502A0 (fi) 1984-02-07
FI840502A FI840502A (fi) 1984-08-08
FI80698B FI80698B (fi) 1990-03-30
FI80698C true FI80698C (fi) 1990-07-10

Family

ID=23844605

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840502A FI80698C (fi) 1983-02-07 1984-02-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara derivat av mitomycin a.

Country Status (29)

Country Link
JP (1) JPS59152384A (da)
KR (1) KR900006854B1 (da)
AT (1) AT385509B (da)
AU (1) AU571193B2 (da)
BE (1) BE898856A (da)
CA (1) CA1252789A (da)
CH (1) CH658658A5 (da)
DD (1) DD233844A5 (da)
DE (1) DE3403922A1 (da)
DK (1) DK161890C (da)
ES (1) ES8607305A1 (da)
FI (1) FI80698C (da)
FR (1) FR2540500B1 (da)
GB (1) GB2134514B (da)
GR (1) GR81455B (da)
HU (1) HU190236B (da)
IE (1) IE56814B1 (da)
IL (1) IL70897A (da)
IT (1) IT1178855B (da)
LU (1) LU85199A1 (da)
NL (1) NL8400338A (da)
NO (1) NO161374C (da)
NZ (1) NZ206932A (da)
OA (1) OA07654A (da)
PH (1) PH20249A (da)
PT (1) PT78067B (da)
SE (1) SE461982B (da)
YU (1) YU44984B (da)
ZA (1) ZA84788B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
CA1282069C (en) * 1985-09-12 1991-03-26 Damon L. Meyer Antibody complexes of hapten-modified diagnostic or therapeutic agents
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63246379A (ja) * 1987-03-31 1988-10-13 Kyowa Hakko Kogyo Co Ltd 7−n,8−n−エチレンマイトマイシン8−イミン類
EP0485904B1 (en) * 1990-11-13 1997-08-20 Kyowa Hakko Kogyo Co., Ltd. Mitomycin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative
NZ199617A (en) * 1981-05-15 1985-08-30 University Patents Inc Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes

Also Published As

Publication number Publication date
GB8402233D0 (en) 1984-02-29
CH658658A5 (de) 1986-11-28
ES8607305A1 (es) 1986-05-16
PT78067B (en) 1986-03-20
GB2134514B (en) 1987-04-01
GR81455B (da) 1984-12-11
FI840502A0 (fi) 1984-02-07
PH20249A (en) 1986-11-10
SE8400628D0 (sv) 1984-02-07
FI840502A (fi) 1984-08-08
DK52484A (da) 1984-08-08
IT8467113A0 (it) 1984-02-07
NL8400338A (nl) 1984-09-03
SE8400628L (sv) 1984-08-08
OA07654A (fr) 1985-05-23
SE461982B (sv) 1990-04-23
DE3403922A1 (de) 1984-08-09
IE840272L (en) 1984-08-07
AU571193B2 (en) 1988-04-14
ATA37684A (de) 1987-09-15
DK161890C (da) 1992-02-03
FR2540500A1 (fr) 1984-08-10
AU2407384A (en) 1984-08-16
NO161374B (no) 1989-05-02
GB2134514A (en) 1984-08-15
YU44984B (en) 1991-06-30
NO840433L (no) 1984-08-08
KR900006854B1 (ko) 1990-09-22
LU85199A1 (fr) 1984-05-30
JPS59152384A (ja) 1984-08-31
HU190236B (en) 1986-08-28
YU21784A (en) 1986-10-31
CA1252789A (en) 1989-04-18
BE898856A (fr) 1984-05-30
DD233844A5 (de) 1986-03-12
ZA84788B (en) 1984-09-26
IL70897A0 (en) 1984-05-31
DK161890B (da) 1991-08-26
AT385509B (de) 1988-04-11
FR2540500B1 (fr) 1987-07-17
PT78067A (en) 1984-03-01
IT1178855B (it) 1987-09-16
ES529478A0 (es) 1986-05-16
DK52484D0 (da) 1984-02-06
IL70897A (en) 1989-01-31
FI80698B (fi) 1990-03-30
KR840007726A (ko) 1984-12-10
NZ206932A (en) 1987-08-31
IE56814B1 (en) 1991-12-18
NO161374C (no) 1989-08-09

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: UNIVERSITY PATENTS, INC.