DE3324771A1 - Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE3324771A1
DE3324771A1 DE19833324771 DE3324771A DE3324771A1 DE 3324771 A1 DE3324771 A1 DE 3324771A1 DE 19833324771 DE19833324771 DE 19833324771 DE 3324771 A DE3324771 A DE 3324771A DE 3324771 A1 DE3324771 A1 DE 3324771A1
Authority
DE
Germany
Prior art keywords
alkyl
group
amino
compounds
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833324771
Other languages
German (de)
English (en)
Inventor
David Edmund Bays
Roger Potters Bar Hertfordshire Hayes
John Wilson Macfarlane Ware Hertfordshire MacKinnon
Barry John Tewin Wood Hertfordshire Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE3324771A1 publication Critical patent/DE3324771A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DE19833324771 1982-07-08 1983-07-08 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Withdrawn DE3324771A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8219746 1982-07-08

Publications (1)

Publication Number Publication Date
DE3324771A1 true DE3324771A1 (de) 1984-01-12

Family

ID=10531541

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833324771 Withdrawn DE3324771A1 (de) 1982-07-08 1983-07-08 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (11)

Country Link
JP (1) JPS5927880A (ja)
AU (1) AU1666583A (ja)
BE (1) BE897247A (ja)
DE (1) DE3324771A1 (ja)
DK (1) DK317283A (ja)
FR (1) FR2532937A1 (ja)
GB (1) GB2124622A (ja)
IT (1) IT8348653A0 (ja)
NL (1) NL8302450A (ja)
SE (1) SE8303913L (ja)
ZA (1) ZA835009B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132541A2 (de) * 1983-07-22 1985-02-13 LUDWIG HEUMANN & CO GMBH Propan-2-ol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0158789A1 (de) * 1984-03-07 1985-10-23 LUDWIG HEUMANN & CO GMBH Diaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567191A (en) * 1983-06-07 1986-01-28 Merck & Co., Inc. Amino-phenyl-thiadiazoledioxides as gastric secretion inhibitors
JP4664074B2 (ja) 2002-10-09 2011-04-06 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドおよびｃｃ−ケモカインレセプターリガンドとしてのチアジアゾールジオキシドおよびチアジアゾールオキシド
ATE406356T1 (de) 2003-12-19 2008-09-15 Schering Corp Thiadiazole als cxc- und cc- chemokinrezeptorliganden
US7671212B2 (en) 2003-12-22 2010-03-02 Schering Corporation Isothiazole dioxides as CXC- and CC-chemokine receptor ligands
JP2009500334A (ja) 2005-06-29 2009-01-08 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドとしてのジ置換オキサジアゾール
ES2353401T3 (es) 2005-06-29 2011-03-01 Schering Corporation Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos del receptor de cxc-quimiocina.
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040696B1 (en) * 1980-04-30 1986-08-27 Merck & Co. Inc. Aminothiadiazoles as gastric secretion inhibitors
US4411899A (en) * 1981-12-21 1983-10-25 Merck & Co., Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132541A2 (de) * 1983-07-22 1985-02-13 LUDWIG HEUMANN & CO GMBH Propan-2-ol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0132541A3 (de) * 1983-07-22 1985-09-25 LUDWIG HEUMANN & CO GMBH Propan-2-ol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0158789A1 (de) * 1984-03-07 1985-10-23 LUDWIG HEUMANN & CO GMBH Diaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4656180A (en) * 1984-03-07 1987-04-07 Ludwig Heumann & Co., Gmbh Diamine derivatives and pharmaceutical preparations containing these compounds

Also Published As

Publication number Publication date
GB2124622A (en) 1984-02-22
ZA835009B (en) 1985-02-27
DK317283A (da) 1984-01-09
AU1666583A (en) 1984-01-12
SE8303913D0 (sv) 1983-07-08
JPS5927880A (ja) 1984-02-14
IT8348653A0 (it) 1983-07-08
SE8303913L (sv) 1984-01-09
FR2532937A1 (fr) 1984-03-16
DK317283D0 (da) 1983-07-08
BE897247A (fr) 1984-01-09
NL8302450A (nl) 1984-02-01
GB8318525D0 (en) 1983-08-10

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee