FR2532937A1 - Nouveaux derives de thiadiazolyl-s-oxyde, procede pour leur preparation et compositions pharmaceutiques les comportant - Google Patents

Nouveaux derives de thiadiazolyl-s-oxyde, procede pour leur preparation et compositions pharmaceutiques les comportant Download PDF

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Publication number
FR2532937A1
FR2532937A1 FR8311402A FR8311402A FR2532937A1 FR 2532937 A1 FR2532937 A1 FR 2532937A1 FR 8311402 A FR8311402 A FR 8311402A FR 8311402 A FR8311402 A FR 8311402A FR 2532937 A1 FR2532937 A1 FR 2532937A1
Authority
FR
France
Prior art keywords
alkyl
group
hydrogen
amino
thiadiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8311402A
Other languages
English (en)
French (fr)
Inventor
Barry John Price
Roger Hayes
David Edmund Bays
John Wilson Macfarla Mackinnon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2532937A1 publication Critical patent/FR2532937A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
FR8311402A 1982-07-08 1983-07-08 Nouveaux derives de thiadiazolyl-s-oxyde, procede pour leur preparation et compositions pharmaceutiques les comportant Withdrawn FR2532937A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8219746 1982-07-08

Publications (1)

Publication Number Publication Date
FR2532937A1 true FR2532937A1 (fr) 1984-03-16

Family

ID=10531541

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8311402A Withdrawn FR2532937A1 (fr) 1982-07-08 1983-07-08 Nouveaux derives de thiadiazolyl-s-oxyde, procede pour leur preparation et compositions pharmaceutiques les comportant

Country Status (11)

Country Link
JP (1) JPS5927880A (ja)
AU (1) AU1666583A (ja)
BE (1) BE897247A (ja)
DE (1) DE3324771A1 (ja)
DK (1) DK317283A (ja)
FR (1) FR2532937A1 (ja)
GB (1) GB2124622A (ja)
IT (1) IT8348653A0 (ja)
NL (1) NL8302450A (ja)
SE (1) SE8303913L (ja)
ZA (1) ZA835009B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567191A (en) * 1983-06-07 1986-01-28 Merck & Co., Inc. Amino-phenyl-thiadiazoledioxides as gastric secretion inhibitors
DE3326545A1 (de) * 1983-07-22 1985-01-31 Ludwig Heumann & Co GmbH, 8500 Nürnberg Propan-2-ol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3408327A1 (de) * 1984-03-07 1985-09-12 Ludwig Heumann & Co GmbH, 8500 Nürnberg Diaminderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE422203T1 (de) 2002-10-09 2009-02-15 Schering Corp Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden
MXPA06007076A (es) 2003-12-19 2006-08-31 Pharmacopeia Drug Discovery Tiadiazoles como ligandos del receptor cxc y cc-quimiocina.
JP4851943B2 (ja) 2003-12-22 2012-01-11 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドおよびｃｃ−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド
EP1912971A2 (en) 2005-06-29 2008-04-23 Shering Corporation Di-substituted oxadiazoles as cxc-chemokine receptor ligands
JP2009500328A (ja) 2005-06-29 2009-01-08 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドとしての５，６−ジ−置換オキサジアゾロピラジンおよびチアジアゾロピラジン
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040696A2 (en) * 1980-04-30 1981-12-02 Merck & Co. Inc. Aminothiadiazoles as gastric secretion inhibitors
EP0082376A2 (en) * 1981-12-21 1983-06-29 Merck & Co. Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040696A2 (en) * 1980-04-30 1981-12-02 Merck & Co. Inc. Aminothiadiazoles as gastric secretion inhibitors
EP0082376A2 (en) * 1981-12-21 1983-06-29 Merck & Co. Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors

Also Published As

Publication number Publication date
IT8348653A0 (it) 1983-07-08
DK317283D0 (da) 1983-07-08
NL8302450A (nl) 1984-02-01
SE8303913D0 (sv) 1983-07-08
DK317283A (da) 1984-01-09
GB8318525D0 (en) 1983-08-10
SE8303913L (sv) 1984-01-09
GB2124622A (en) 1984-02-22
AU1666583A (en) 1984-01-12
JPS5927880A (ja) 1984-02-14
DE3324771A1 (de) 1984-01-12
ZA835009B (en) 1985-02-27
BE897247A (fr) 1984-01-09

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