BE897247A - Nouveau composes heterocycliques - Google Patents

Nouveau composes heterocycliques Download PDF

Info

Publication number
BE897247A
BE897247A BE0/211139A BE211139A BE897247A BE 897247 A BE897247 A BE 897247A BE 0/211139 A BE0/211139 A BE 0/211139A BE 211139 A BE211139 A BE 211139A BE 897247 A BE897247 A BE 897247A
Authority
BE
Belgium
Prior art keywords
group
alkyl
amino
hydrogen
thiadiazol
Prior art date
Application number
BE0/211139A
Other languages
English (en)
French (fr)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE897247A publication Critical patent/BE897247A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
BE0/211139A 1982-07-08 1983-07-08 Nouveau composes heterocycliques BE897247A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8219746 1982-07-08

Publications (1)

Publication Number Publication Date
BE897247A true BE897247A (fr) 1984-01-09

Family

ID=10531541

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/211139A BE897247A (fr) 1982-07-08 1983-07-08 Nouveau composes heterocycliques

Country Status (11)

Country Link
JP (1) JPS5927880A (ja)
AU (1) AU1666583A (ja)
BE (1) BE897247A (ja)
DE (1) DE3324771A1 (ja)
DK (1) DK317283A (ja)
FR (1) FR2532937A1 (ja)
GB (1) GB2124622A (ja)
IT (1) IT8348653A0 (ja)
NL (1) NL8302450A (ja)
SE (1) SE8303913L (ja)
ZA (1) ZA835009B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567191A (en) * 1983-06-07 1986-01-28 Merck & Co., Inc. Amino-phenyl-thiadiazoledioxides as gastric secretion inhibitors
DE3326545A1 (de) * 1983-07-22 1985-01-31 Ludwig Heumann & Co GmbH, 8500 Nürnberg Propan-2-ol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3408327A1 (de) * 1984-03-07 1985-09-12 Ludwig Heumann & Co GmbH, 8500 Nürnberg Diaminderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE422203T1 (de) 2002-10-09 2009-02-15 Schering Corp Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden
MXPA06007076A (es) 2003-12-19 2006-08-31 Pharmacopeia Drug Discovery Tiadiazoles como ligandos del receptor cxc y cc-quimiocina.
JP4851943B2 (ja) 2003-12-22 2012-01-11 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドおよびｃｃ−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド
EP1912971A2 (en) 2005-06-29 2008-04-23 Shering Corporation Di-substituted oxadiazoles as cxc-chemokine receptor ligands
JP2009500328A (ja) 2005-06-29 2009-01-08 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドとしての５，６−ジ−置換オキサジアゾロピラジンおよびチアジアゾロピラジン
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175201D1 (en) * 1980-04-30 1986-10-02 Merck & Co Inc Aminothiadiazoles as gastric secretion inhibitors
US4411899A (en) * 1981-12-21 1983-10-25 Merck & Co., Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors

Also Published As

Publication number Publication date
IT8348653A0 (it) 1983-07-08
DK317283D0 (da) 1983-07-08
NL8302450A (nl) 1984-02-01
SE8303913D0 (sv) 1983-07-08
DK317283A (da) 1984-01-09
GB8318525D0 (en) 1983-08-10
SE8303913L (sv) 1984-01-09
GB2124622A (en) 1984-02-22
AU1666583A (en) 1984-01-12
FR2532937A1 (fr) 1984-03-16
JPS5927880A (ja) 1984-02-14
DE3324771A1 (de) 1984-01-12
ZA835009B (en) 1985-02-27

Similar Documents

Publication Publication Date Title
CA2552565C (fr) Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
EP1720848B1 (fr) Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en tant qu'inhibiteurs de l'enzyme faah
KR960016119B1 (ko) 히드록시메틸기 및 치환된 페닐기에 의해 치환된 신규의 이미다졸리딘, 이들의 제조방법, 의약으로서 이들의 용도, 이들을 함유하는 제약조성물 및 이들의 제조를 위한 중간체
LU84561A1 (fr) 2-(4-((4,4,-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyrimidines
FR2639942A1 (fr) Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
BE897247A (fr) Nouveau composes heterocycliques
EP0576619B1 (fr) Compositions therapeutiques a base de derives de 1,2-dithiole-3-thione
EP1966167B1 (fr) Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique.
EP0115979B1 (fr) Nouveaux dérivés du 1H,3H-pyrrolo (1,2-c) thiazole leur préparation et les médicaments qui les contiennent
CH655104A5 (fr) Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant.
EP0049049B1 (en) 5-amino-tetrazole derivatives, processes for their preparation and pharmaceutical compositions containing them
EP0101380A2 (fr) Nicotinamide 1-oxyde N-substitué, ses sels, procédé pour leur préparation et compositions pharmaceutiques en contenant
JPH0446953B2 (ja)
FR2464259A1 (fr) Nouvelles 5-(2-chlorophenyl)-6h-1,3,4-thiadiazine-2-amines, utiles notamment comme anticonvulsivants, et leur procede de preparation
FR2516510A1 (fr) Derives de la (trimethoxy-3,4,5-cinnamoyl)-1-aminocarbonylethyl-4-piperazine substituee utilisables en pharmacie et procede pour leur preparation
US4507296A (en) Tetrazoles, pharmaceutical use and compositions
FR2719047A1 (fr) Nouveaux dérivés de benzylamines, leur procédé de fabrication et les compositions pharmaceutiques les renfermant.
FR2521993A1 (fr) Composes heterocycliques azotes, leur preparation et leur utilisation therapeutique en tant qu'antagonistes de l'histamine
BE898403A (fr) Nouveaux derives d'ethene-diamine et de guanidine.
EP0082058A1 (fr) Ethers d'oximes de pyridyl-1 pentanone-3, leur procédé de préparation et leur utilisation comme médicament
US4585781A (en) Heterocyclic derivatives
FR2508445A1 (fr) Nouveaux derives de benzoyl-phenyl-piperidine, leur procede de preparation et leur application, notamment en therapeutique
ITMI990456A1 (it) Composti eterociclici ad attivita' antitumorale
FR2539414A1 (fr) Derives de la pyrimidine, leur procede de preparation et les medicaments ayant une activite sur le systeme nerveux central qui en contiennent
FR2499569A1 (fr) Nouveaux derives de 1-benzyl- 4-(4-(2-pyrimidinylamino)benzyl)-2,3- dioxopiperazines, leurs sels, un procede de preparation de ces derives et sels et un agent carcinostatique les contenant

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GLAXO GROUP LTD

Effective date: 19860731