DE3248678A1 - Neue bicyclische verbindungen und verfahren zu ihrer herstellung - Google Patents
Neue bicyclische verbindungen und verfahren zu ihrer herstellungInfo
- Publication number
- DE3248678A1 DE3248678A1 DE19823248678 DE3248678A DE3248678A1 DE 3248678 A1 DE3248678 A1 DE 3248678A1 DE 19823248678 DE19823248678 DE 19823248678 DE 3248678 A DE3248678 A DE 3248678A DE 3248678 A1 DE3248678 A1 DE 3248678A1
- Authority
- DE
- Germany
- Prior art keywords
- dioxolan
- oxo
- group
- methyl
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU814017A HU185493B (en) | 1981-12-30 | 1981-12-30 | Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3248678A1 true DE3248678A1 (de) | 1983-07-07 |
Family
ID=10966528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19823248678 Withdrawn DE3248678A1 (de) | 1981-12-30 | 1982-12-30 | Neue bicyclische verbindungen und verfahren zu ihrer herstellung |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS58118588A (es) |
AT (1) | AT375944B (es) |
AU (1) | AU9197382A (es) |
BE (1) | BE895488A (es) |
CA (1) | CA1192202A (es) |
DE (1) | DE3248678A1 (es) |
ES (1) | ES518725A0 (es) |
FI (1) | FI824518L (es) |
FR (1) | FR2519002A1 (es) |
GB (1) | GB2112391B (es) |
GR (1) | GR78431B (es) |
HU (1) | HU185493B (es) |
IT (1) | IT1210971B (es) |
LU (1) | LU84564A1 (es) |
NL (1) | NL8205065A (es) |
PL (1) | PL239887A1 (es) |
SE (1) | SE8207480L (es) |
ZA (1) | ZA829600B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1198440A (en) * | 1982-04-08 | 1985-12-24 | Choung U. Kim | Carbapenem antibiotics |
JPS6028981A (ja) * | 1983-07-27 | 1985-02-14 | Shionogi & Co Ltd | ジオキソラニルペネムカルボン酸誘導体 |
CA2315056A1 (en) * | 1997-12-16 | 1999-06-24 | Terutaka Hashizume | Carbapenem derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5625110A (en) * | 1978-12-18 | 1981-03-10 | Bristol Myers Co | Antibacterial |
IE52147B1 (en) * | 1980-03-27 | 1987-07-08 | Merck & Co Inc | 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation |
JPS57176982A (en) * | 1981-04-24 | 1982-10-30 | Shionogi & Co Ltd | Dioxolanylazetidinone compound, its preparation and use |
-
1981
- 1981-12-30 HU HU814017A patent/HU185493B/hu not_active IP Right Cessation
-
1982
- 1982-12-10 AT AT0450982A patent/AT375944B/de not_active IP Right Cessation
- 1982-12-28 JP JP57235159A patent/JPS58118588A/ja active Pending
- 1982-12-28 BE BE1/10675A patent/BE895488A/fr not_active IP Right Cessation
- 1982-12-29 FR FR8221976A patent/FR2519002A1/fr not_active Withdrawn
- 1982-12-29 LU LU84564A patent/LU84564A1/fr unknown
- 1982-12-29 SE SE8207480A patent/SE8207480L/xx not_active Application Discontinuation
- 1982-12-30 PL PL23988782A patent/PL239887A1/xx unknown
- 1982-12-30 ES ES518725A patent/ES518725A0/es active Granted
- 1982-12-30 AU AU91973/82A patent/AU9197382A/en not_active Abandoned
- 1982-12-30 GB GB08236912A patent/GB2112391B/en not_active Expired
- 1982-12-30 NL NL8205065A patent/NL8205065A/nl not_active Application Discontinuation
- 1982-12-30 DE DE19823248678 patent/DE3248678A1/de not_active Withdrawn
- 1982-12-30 CA CA000418737A patent/CA1192202A/en not_active Expired
- 1982-12-30 ZA ZA829600A patent/ZA829600B/xx unknown
- 1982-12-30 GR GR70186A patent/GR78431B/el unknown
- 1982-12-30 FI FI824518A patent/FI824518L/fi not_active Application Discontinuation
- 1982-12-30 IT IT8225065A patent/IT1210971B/it active
Also Published As
Publication number | Publication date |
---|---|
FI824518A0 (fi) | 1982-12-30 |
ES8405797A1 (es) | 1984-06-16 |
AT375944B (de) | 1984-09-25 |
FI824518L (fi) | 1983-07-01 |
JPS58118588A (ja) | 1983-07-14 |
AU9197382A (en) | 1983-07-07 |
LU84564A1 (fr) | 1984-10-22 |
CA1192202A (en) | 1985-08-20 |
PL239887A1 (en) | 1984-01-02 |
ZA829600B (en) | 1983-10-26 |
SE8207480D0 (sv) | 1982-12-29 |
ES518725A0 (es) | 1984-06-16 |
GR78431B (es) | 1984-09-27 |
FR2519002A1 (fr) | 1983-07-01 |
ATA450982A (de) | 1984-02-15 |
GB2112391A (en) | 1983-07-20 |
IT1210971B (it) | 1989-09-29 |
IT8225065A0 (it) | 1982-12-30 |
HU185493B (en) | 1985-02-28 |
NL8205065A (nl) | 1983-07-18 |
GB2112391B (en) | 1985-10-16 |
SE8207480L (sv) | 1983-07-01 |
BE895488A (fr) | 1983-06-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE19916108C1 (de) | Mit Zuckerresten substituierte 1,4-Benzothiazepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und deren Verwendung | |
CH634579A5 (en) | Process for preparing cephem compounds | |
EP0126709A1 (de) | Verfahren zur Herstellung von optisch aktiven Azetidinonen | |
DE69916030T2 (de) | Verfahren zur herstellung optisch aktiver threo-3-amino-1,2-epoxyverbindungen | |
CH617440A5 (es) | ||
DE3248678A1 (de) | Neue bicyclische verbindungen und verfahren zu ihrer herstellung | |
DE2633561A1 (de) | Azabicycloheptan-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate | |
CH642968A5 (de) | Cephalosporin-analoge und verfahren zu deren herstellung. | |
EP0000057A1 (de) | Selektiv geschützte 4,6-Di-O-(aminoglycosyl)-1,3-diaminocyclitole | |
DE3026602C2 (es) | ||
DE60032453T2 (de) | Ein verfahren zur synthese von ritonavir | |
DE3248675A1 (de) | Verfahren zur herstellung heterocyclischer essigsaeurederivate (ii) | |
DE19515976C1 (de) | beta-Azidoethansulfonylazid, Verfahren zu seiner Herstellung und seine Verwendung in Verfahren zur Herstellung von Taurinamid und Taurolidin | |
CH621336A5 (es) | ||
CH655315A5 (de) | Verfahren zur herstellung einer aminolactoncarbonsaeure. | |
CH641448A5 (de) | Verfahren zur herstellung von beta-lactamen. | |
DE2707404C3 (de) | Verfahren zur Herstellung von 5,6-Dehydropenicillinen | |
DE2534601A1 (de) | Verfahren zur herstellung von camptothecin-aehnlichen verbindungen | |
CH655926A5 (de) | Heterocyclische essigsaeuren und verfahren zu ihrer herstellung. | |
EP0259268A1 (de) | Verfahren zur Herstellung optisch aktiver Beta-Lactame | |
EP0101602B1 (de) | In 6-Stellung unsubstituierte 7-Oxo-4-oxa-diazabicyclo-(3.2.0)-hept-2-en Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Zwischenprodukte zur Synthese von beta-Lactamantibiotika | |
DE3248677A1 (de) | Verfahren zur herstellung bicyclischer verbindungen (ii) | |
DE3248676A1 (de) | Neue bicyclische verbindungen und verfahren zu ihrer herstellung (i) | |
DE2639397A1 (de) | 7-oxo-1,3-diazabicyclo eckige klammer auf 3.2.o eckige klammer zu heptan-2-carbonsaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte | |
DE2615621A1 (de) | Beta-lactam-antibiotika und -zwischenprodukte sowie ihr herstellungsverfahren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8139 | Disposal/non-payment of the annual fee |