DE3208057C2 - ß-1,3-Glucan - Google Patents
ß-1,3-GlucanInfo
- Publication number
- DE3208057C2 DE3208057C2 DE3208057A DE3208057A DE3208057C2 DE 3208057 C2 DE3208057 C2 DE 3208057C2 DE 3208057 A DE3208057 A DE 3208057A DE 3208057 A DE3208057 A DE 3208057A DE 3208057 C2 DE3208057 C2 DE 3208057C2
- Authority
- DE
- Germany
- Prior art keywords
- glucan
- small
- small beta
- beta
- culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920002498 Beta-glucan Polymers 0.000 title claims abstract description 53
- 238000000034 method Methods 0.000 claims abstract description 17
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- 239000000284 extract Substances 0.000 claims abstract description 14
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- 238000002523 gelfiltration Methods 0.000 claims description 6
- 241000383853 Pseudoplectania nigrella Species 0.000 claims description 4
- 238000002955 isolation Methods 0.000 claims 1
- 229920001503 Glucan Polymers 0.000 abstract description 4
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- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 101000763602 Manilkara zapota Thaumatin-like protein 1 Proteins 0.000 description 2
- 101000763586 Manilkara zapota Thaumatin-like protein 1a Proteins 0.000 description 2
- 101000966653 Musa acuminata Glucan endo-1,3-beta-glucosidase Proteins 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
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- 241000222355 Trametes versicolor Species 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
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- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 2
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- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56032797A JPS57146719A (en) | 1981-03-06 | 1981-03-06 | Preparation of antitumor substance |
| JP13903981A JPS5840301A (ja) | 1981-09-03 | 1981-09-03 | 抗腫瘍活性を有するβ−１，３−グルカン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3208057A1 DE3208057A1 (de) | 1982-09-16 |
| DE3208057C2 true DE3208057C2 (de) | 1987-02-19 |
Family
ID=26371382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3208057A Expired DE3208057C2 (de) | 1981-03-06 | 1982-03-05 | ß-1,3-Glucan |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4454289A (Sortimente) |
| KR (1) | KR870001814B1 (Sortimente) |
| AU (1) | AU549553B2 (Sortimente) |
| CA (1) | CA1183530A (Sortimente) |
| CH (1) | CH660026A5 (Sortimente) |
| DE (1) | DE3208057C2 (Sortimente) |
| ES (1) | ES8302776A1 (Sortimente) |
| FR (1) | FR2501232A1 (Sortimente) |
| GB (1) | GB2094324B (Sortimente) |
| IT (1) | IT1150622B (Sortimente) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6023401A (ja) * | 1983-03-09 | 1985-02-06 | Toyo Soda Mfg Co Ltd | 多糖類およびその製造法 |
| JPH0692441B2 (ja) * | 1986-03-03 | 1994-11-16 | 株式会社林原生物化学研究所 | β−Ｄ−グルカンとその製造方法及び用途 |
| FI885955A7 (fi) * | 1987-12-23 | 1989-06-24 | Weston George Ltd | Ny b-1,3-glukanexopolysackarid och foerfarande foer framstaellning av densamma. |
| JP2681653B2 (ja) * | 1988-05-13 | 1997-11-26 | 台糖株式会社 | 抗エイズウィルス剤 |
| US5189028A (en) * | 1989-02-20 | 1993-02-23 | Taito Co., Ltd. | Composition and method to enhance the efficacy of a fish vaccine and to stimulate the immune system of fish |
| GB9007730D0 (en) * | 1990-04-05 | 1990-06-06 | Cerestar Holding Bv | Therapeutic compound and composition |
| CA2081025A1 (en) * | 1991-02-21 | 1992-08-22 | Kazuhiro Inoue | Carboxymethylmannoglucans and derivatives thereof |
| JP3167649B2 (ja) * | 1997-07-25 | 2001-05-21 | 株式会社資生堂 | タンパク質を除去したβ−１，３グルカン及びこれを主成分とするゲルからなる超音波診断装置のプローブ用接触媒体 |
| US6251877B1 (en) * | 1998-03-24 | 2001-06-26 | Pacific Corporation | Composition for external application containing a β-1,6-branched-β-1,3-glucan |
| US7507724B2 (en) | 2001-01-16 | 2009-03-24 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| EP1357919B1 (en) * | 2001-01-16 | 2017-04-05 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US7906492B2 (en) * | 2001-01-16 | 2011-03-15 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| NO20014256D0 (no) | 2001-09-03 | 2001-09-03 | Bjoern Kristiansen | Fremstilling av immunstimulerende forbindelse |
| US7514085B2 (en) * | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| MX2007014219A (es) * | 2005-05-13 | 2008-04-08 | Medimush As | Productos alimenticios o forrajeros que comprenden material fungico. |
| US9072776B2 (en) * | 2005-06-15 | 2015-07-07 | Glycanova As | Anti-cancer combination treatment and kit-of-parts |
| US20090005340A1 (en) * | 2005-06-15 | 2009-01-01 | Medimush A/S | Bioactive Agents Produced By Submerged Cultivation of a Basidiomycete Cell |
| US8323644B2 (en) * | 2006-01-17 | 2012-12-04 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US20090053221A1 (en) * | 2006-01-17 | 2009-02-26 | Cheung Nai-Kong V | Immune response enhancing glucan |
| US8075839B2 (en) | 2006-09-15 | 2011-12-13 | Haynes International, Inc. | Cobalt-chromium-iron-nickel alloys amenable to nitride strengthening |
| DE102015224162B4 (de) * | 2015-12-03 | 2017-11-30 | Siemens Healthcare Gmbh | Verfahren zur Ermittlung einer eine Bewegung in einem zumindest teilweise bewegten Untersuchungsbereich beschreibenden Bewegungsinformation und Magnetresonanzeinrichtung |
| CN112076209A (zh) * | 2019-06-14 | 2020-12-15 | 青岛海洋生物医药研究院股份有限公司 | 一种β-葡聚糖组合物及其用途 |
| CN111593034B (zh) * | 2020-06-24 | 2022-07-05 | 江南大学 | 利用β-1,6-葡聚糖酶制备低聚龙胆糖的方法及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3301848A (en) * | 1962-10-30 | 1967-01-31 | Pillsbury Co | Polysaccharides and methods for production thereof |
| JPS5339519B1 (Sortimente) * | 1970-07-31 | 1978-10-21 | ||
| JPS5461112A (en) * | 1977-10-24 | 1979-05-17 | Ono Pharmaceut Co Ltd | Oncostatic polysaccharide* its preparation* and oncostatic drugs containing it as an effective component |
-
1982
- 1982-02-23 US US06/351,364 patent/US4454289A/en not_active Expired - Lifetime
- 1982-03-01 GB GB8205928A patent/GB2094324B/en not_active Expired
- 1982-03-05 ES ES510184A patent/ES8302776A1/es not_active Expired
- 1982-03-05 AU AU81148/82A patent/AU549553B2/en not_active Ceased
- 1982-03-05 KR KR8200949A patent/KR870001814B1/ko not_active Expired
- 1982-03-05 CA CA000397674A patent/CA1183530A/en not_active Expired
- 1982-03-05 IT IT19987/82A patent/IT1150622B/it active
- 1982-03-05 FR FR8203720A patent/FR2501232A1/fr active Granted
- 1982-03-05 DE DE3208057A patent/DE3208057C2/de not_active Expired
- 1982-03-05 CH CH1376/82A patent/CH660026A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3208057A1 (de) | 1982-09-16 |
| GB2094324B (en) | 1984-09-19 |
| GB2094324A (en) | 1982-09-15 |
| AU549553B2 (en) | 1986-01-30 |
| KR870001814B1 (ko) | 1987-10-13 |
| AU8114882A (en) | 1982-09-09 |
| US4454289A (en) | 1984-06-12 |
| CH660026A5 (de) | 1987-03-13 |
| ES510184A0 (es) | 1983-01-16 |
| ES8302776A1 (es) | 1983-01-16 |
| KR830009224A (ko) | 1983-12-19 |
| CA1183530A (en) | 1985-03-05 |
| FR2501232A1 (fr) | 1982-09-10 |
| FR2501232B1 (Sortimente) | 1985-03-15 |
| IT8219987A0 (it) | 1982-03-05 |
| IT1150622B (it) | 1986-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |