KR830009224A - 고분자 β-1,3-글루칸의 제조방법 - Google Patents

고분자 β-1,3-글루칸의 제조방법 Download PDF

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Publication number
KR830009224A
KR830009224A KR1019820000949A KR820000949A KR830009224A KR 830009224 A KR830009224 A KR 830009224A KR 1019820000949 A KR1019820000949 A KR 1019820000949A KR 820000949 A KR820000949 A KR 820000949A KR 830009224 A KR830009224 A KR 830009224A
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KR
South Korea
Prior art keywords
glucan
pseudoplexania
strain
polymer
filtered
Prior art date
Application number
KR1019820000949A
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English (en)
Other versions
KR870001814B1 (ko
Inventor
가즈오 나카지마
요시아키 히라타
히로유키 우지다
도모고 시오미
즈토무 다니구지
아키라 오오바야시
오사무 다나베
티구마 사사기
Original Assignee
오오미야타카시
타카라 슈죠오 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56032797A external-priority patent/JPS57146719A/ja
Priority claimed from JP13903981A external-priority patent/JPS5840301A/ja
Application filed by 오오미야타카시, 타카라 슈죠오 가부시기가이샤 filed Critical 오오미야타카시
Publication of KR830009224A publication Critical patent/KR830009224A/ko
Application granted granted Critical
Publication of KR870001814B1 publication Critical patent/KR870001814B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Abstract

내용 없음

Description

고분자 β-1,3-글루칸의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명 물질의 적외선 흡수 스펙라를 나타낸 것임.

Claims (5)

  1. 하기 구조식의 글루코피라노스 단위체가 반복된 고분자 β-1,3-글루칸.
  2. 제1항에 있어서, 상기 β-1,3-글루칸이, 항종양성(β-1,3-글루칸을 생성할 수 있고 디스코미세테스 강의 슈도플렉타니아 속에 속하는 균주의 자실체 및/또는 균사체의 추출물로부터 또는 상기 균주가배양된 배지로부터 분리되는 것을 특징으로 하는 고분자 β-1,3-글루칸.
  3. 제2항에 있어서, 상기 균주가 슈도플렉타니아 니그렐라(pers) 퍽켈 K-1426(FERM-p 5803, ATCC 20609)인 것을 특징으로 하는 β-1,3-글루칸.
  4. β-1,3-글루칸을 생성할 수 있고 디스코미세테스 강의 슈도플렉타니아 속에 속하는 균주의 균사체 또는 자실체의 추출액 또는 배지로부터 여과된 육즙을 형성한 다음, 정제된 형태로 여과된 육즙 또는 추출액으로부터 β-1,3-글루칸을 회수하여 하기 구조식으로 갖는 글루코 피라노스 단위체가 반복된 고분자 β-1,3-글루칸을 제조하는 방법.
  5. 제4항에 있어서, 균주가 슈도플렉타니아 니그렐라(Pers) 퍽켈 K-1426(FERM-P-5803, ATCC 20609)인 것을 특징으로하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임
KR8200949A 1981-03-06 1982-03-05 고분자 β-1, 3-글루칸의 제조방법 KR870001814B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP32797 1981-03-06
JP56032797A JPS57146719A (en) 1981-03-06 1981-03-06 Preparation of antitumor substance
JP13903981A JPS5840301A (ja) 1981-09-03 1981-09-03 抗腫瘍活性を有するβ−１，３−グルカン
JP139039 1986-06-13

Publications (2)

Publication Number Publication Date
KR830009224A true KR830009224A (ko) 1983-12-19
KR870001814B1 KR870001814B1 (ko) 1987-10-13

Family

ID=26371382

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8200949A KR870001814B1 (ko) 1981-03-06 1982-03-05 고분자 β-1, 3-글루칸의 제조방법

Country Status (10)

Country Link
US (1) US4454289A (ko)
KR (1) KR870001814B1 (ko)
AU (1) AU549553B2 (ko)
CA (1) CA1183530A (ko)
CH (1) CH660026A5 (ko)
DE (1) DE3208057A1 (ko)
ES (1) ES510184A0 (ko)
FR (1) FR2501232A1 (ko)
GB (1) GB2094324B (ko)
IT (1) IT1150622B (ko)

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JPS6023401A (ja) * 1983-03-09 1985-02-06 Toyo Soda Mfg Co Ltd 多糖類およびその製造法
JPH0692441B2 (ja) * 1986-03-03 1994-11-16 株式会社林原生物化学研究所 β−Ｄ−グルカンとその製造方法及び用途
FI885955A (fi) * 1987-12-23 1989-06-24 Weston George Ltd Ny b-1,3-glukanexopolysackarid och foerfarande foer framstaellning av densamma.
JP2681653B2 (ja) * 1988-05-13 1997-11-26 台糖株式会社 抗エイズウィルス剤
US5189028A (en) * 1989-02-20 1993-02-23 Taito Co., Ltd. Composition and method to enhance the efficacy of a fish vaccine and to stimulate the immune system of fish
GB9007730D0 (en) * 1990-04-05 1990-06-06 Cerestar Holding Bv Therapeutic compound and composition
WO1992014759A1 (en) * 1991-02-21 1992-09-03 Drug Delivery System Institute, Ltd. Carboxymethylmannoglucan and derivative thereof
JP3167649B2 (ja) * 1997-07-25 2001-05-21 株式会社資生堂 タンパク質を除去したβ−１，３グルカン及びこれを主成分とするゲルからなる超音波診断装置のプローブ用接触媒体
US6251877B1 (en) * 1998-03-24 2001-06-26 Pacific Corporation Composition for external application containing a β-1,6-branched-β-1,3-glucan
US7906492B2 (en) * 2001-01-16 2011-03-15 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US7507724B2 (en) 2001-01-16 2009-03-24 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
CA2434938C (en) * 2001-01-16 2012-02-28 Sloan-Kettering Institute For Cancer Research Compositions of glucan and a monoclonal antibody which exhibit an enhancement of the anti tumor activity of the antibody
NO20014256D0 (no) 2001-09-03 2001-09-03 Bjoern Kristiansen Fremstilling av immunstimulerende forbindelse
US7514085B2 (en) * 2004-07-16 2009-04-07 Medimush A/S Immune modulating compounds from fungi
EP1885866A1 (en) * 2005-05-13 2008-02-13 Medimush A/S Feed or food products comprising fungal material
EP1896600A2 (en) * 2005-06-15 2008-03-12 Medimush A/S Anti-cancer combination treatment and kit-of-part
EP1896601A1 (en) * 2005-06-15 2008-03-12 Medimush A/S Bioactive agents produced by submerged cultivation of a basidiomycete cell
US8323644B2 (en) * 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US20090053221A1 (en) * 2006-01-17 2009-02-26 Cheung Nai-Kong V Immune response enhancing glucan
US8075839B2 (en) 2006-09-15 2011-12-13 Haynes International, Inc. Cobalt-chromium-iron-nickel alloys amenable to nitride strengthening
DE102015224162B4 (de) * 2015-12-03 2017-11-30 Siemens Healthcare Gmbh Verfahren zur Ermittlung einer eine Bewegung in einem zumindest teilweise bewegten Untersuchungsbereich beschreibenden Bewegungsinformation und Magnetresonanzeinrichtung
CN112076209A (zh) * 2019-06-14 2020-12-15 青岛海洋生物医药研究院股份有限公司 一种β-葡聚糖组合物及其用途
CN111593034B (zh) * 2020-06-24 2022-07-05 江南大学 利用β-1,6-葡聚糖酶制备低聚龙胆糖的方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3301848A (en) * 1962-10-30 1967-01-31 Pillsbury Co Polysaccharides and methods for production thereof
JPS5339519B1 (ko) * 1970-07-31 1978-10-21
JPS5461112A (en) * 1977-10-24 1979-05-17 Ono Pharmaceut Co Ltd Oncostatic polysaccharide* its preparation* and oncostatic drugs containing it as an effective component

Also Published As

Publication number Publication date
FR2501232A1 (fr) 1982-09-10
DE3208057C2 (ko) 1987-02-19
AU549553B2 (en) 1986-01-30
ES8302776A1 (es) 1983-01-16
FR2501232B1 (ko) 1985-03-15
CH660026A5 (de) 1987-03-13
AU8114882A (en) 1982-09-09
IT8219987A0 (it) 1982-03-05
US4454289A (en) 1984-06-12
IT1150622B (it) 1986-12-17
CA1183530A (en) 1985-03-05
ES510184A0 (es) 1983-01-16
KR870001814B1 (ko) 1987-10-13
GB2094324A (en) 1982-09-15
GB2094324B (en) 1984-09-19
DE3208057A1 (de) 1982-09-16

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