DE3139238A1 - Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung - Google Patents

Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung

Info

Publication number
DE3139238A1
DE3139238A1 DE19813139238 DE3139238A DE3139238A1 DE 3139238 A1 DE3139238 A1 DE 3139238A1 DE 19813139238 DE19813139238 DE 19813139238 DE 3139238 A DE3139238 A DE 3139238A DE 3139238 A1 DE3139238 A1 DE 3139238A1
Authority
DE
Germany
Prior art keywords
chloro
formula
optically active
methyl
bromo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19813139238
Other languages
German (de)
English (en)
Inventor
Hans-Georg Dipl.-Chem. Dr. 6700 Ludwigshafen Ernst
Joachim Dipl.-Chem. Dr. 6701 Neuhofen Paust
Friedrich Dipl.-Chem. Dr. 6706 Wachenheim Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6143251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3139238(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BASF SE filed Critical BASF SE
Priority to DE19813139238 priority Critical patent/DE3139238A1/de
Priority to DE8282108913T priority patent/DE3261632D1/de
Priority to EP82108913A priority patent/EP0076448B1/de
Priority to US06/430,695 priority patent/US4518813A/en
Priority to JP57171108A priority patent/JPS5874623A/ja
Priority to CA000412662A priority patent/CA1191157A/en
Publication of DE3139238A1 publication Critical patent/DE3139238A1/de
Priority to JP1240888A priority patent/JPH02218624A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/01—Acyclic saturated compounds containing halogen atoms containing chlorine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/075—Acyclic saturated compounds containing halogen atoms containing bromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE19813139238 1981-10-02 1981-10-02 Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung Withdrawn DE3139238A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19813139238 DE3139238A1 (de) 1981-10-02 1981-10-02 Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung
DE8282108913T DE3261632D1 (en) 1981-10-02 1982-09-27 Optically active components for the synthesis of the side chain of (r,r,r)-alpha-tocopherol and process for their preparation
EP82108913A EP0076448B1 (de) 1981-10-02 1982-09-27 Optisch aktive Bausteine für die Synthese der Seitenkette von (R,R,R)-Alpha-Tocopherol sowie Verfahren zu deren Herstellung
US06/430,695 US4518813A (en) 1981-10-02 1982-09-30 Optically active units for the synthesis of the side chain of (R,R,R)-α-tocopherol and their preparation
JP57171108A JPS5874623A (ja) 1981-10-02 1982-10-01 （Ｒ，Ｒ，Ｒ）―α―トコフェロールの側鎖合成のための光学活性中間体の製法
CA000412662A CA1191157A (en) 1981-10-02 1982-10-01 Synthesis of (2r,6r)-1-chloro-2,6,10-trimethyl- urdicane
JP1240888A JPH02218624A (ja) 1981-10-02 1989-09-19 新規な光学活性プロパン誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813139238 DE3139238A1 (de) 1981-10-02 1981-10-02 Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
DE3139238A1 true DE3139238A1 (de) 1983-04-21

Family

ID=6143251

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19813139238 Withdrawn DE3139238A1 (de) 1981-10-02 1981-10-02 Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung
DE8282108913T Expired DE3261632D1 (en) 1981-10-02 1982-09-27 Optically active components for the synthesis of the side chain of (r,r,r)-alpha-tocopherol and process for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8282108913T Expired DE3261632D1 (en) 1981-10-02 1982-09-27 Optically active components for the synthesis of the side chain of (r,r,r)-alpha-tocopherol and process for their preparation

Country Status (5)

Country Link
US (1) US4518813A (forum.php)
EP (1) EP0076448B1 (forum.php)
JP (2) JPS5874623A (forum.php)
CA (1) CA1191157A (forum.php)
DE (2) DE3139238A1 (forum.php)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7216043B2 (ja) * 2020-04-21 2023-01-31 信越化学工業株式会社 ６－イソプロペニル－３－メチル－９－デセニル＝アセテートの製造方法及びその中間体
JPWO2022158496A1 (forum.php) 2021-01-21 2022-07-28
EP4321910A4 (en) 2021-04-08 2025-03-26 Furukawa Electric Co., Ltd. Optical fiber

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1040523B (de) * 1955-04-04 1958-10-09 Air Liquide Verfahren zur Herstellung von 1-Chlor-4-brombutan
DE1812268A1 (de) * 1968-12-03 1970-06-25 Technochemie Gmbh Verfahren zur Herstellung von isomerenfreien hoehermolekularen,sekundaeren Alkylbromiden
BE787967A (fr) * 1971-08-25 1973-02-26 May & Baker Ltd Derives de la phenothiazine antispastiques
ZA739471B (en) * 1972-12-22 1974-08-28 Hoffmann La Roche Chromane derivatives
US4026907A (en) * 1973-11-19 1977-05-31 Hoffmann-La Roche Inc. Antioxidant chroman compounds
US4000174A (en) * 1974-04-29 1976-12-28 Zoecon Corporation Novel compounds
US4191842A (en) * 1975-01-27 1980-03-04 Hoffmann-La Roche Inc. Protected alcohols
US4206156A (en) * 1976-07-27 1980-06-03 Fujisawa Pharmaceutical Company, Limited Hydroxyaminohydrocarbonphosphonic acids
FR2455017A1 (fr) * 1979-04-26 1980-11-21 Anvar Procede de preparation du chloro-3 methyl-2 propanol optiquement actif
JPS6030666B2 (ja) * 1980-08-20 1985-07-17 鐘淵化学工業株式会社 光学活性メルカプトカルボン酸の製造法

Also Published As

Publication number Publication date
EP0076448A1 (de) 1983-04-13
JPS5874623A (ja) 1983-05-06
CA1191157A (en) 1985-07-30
DE3261632D1 (en) 1985-01-31
JPH0227973B2 (forum.php) 1990-06-20
US4518813A (en) 1985-05-21
JPH02218624A (ja) 1990-08-31
EP0076448B1 (de) 1984-12-19

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