DE3115086A1 - "dextromethorphan enthaltende pharamzeutische zusammensetzung und die verwendung von dextromethorphan zur schmerzbekaempfung" - Google Patents
"dextromethorphan enthaltende pharamzeutische zusammensetzung und die verwendung von dextromethorphan zur schmerzbekaempfung"Info
- Publication number
- DE3115086A1 DE3115086A1 DE19813115086 DE3115086A DE3115086A1 DE 3115086 A1 DE3115086 A1 DE 3115086A1 DE 19813115086 DE19813115086 DE 19813115086 DE 3115086 A DE3115086 A DE 3115086A DE 3115086 A1 DE3115086 A1 DE 3115086A1
- Authority
- DE
- Germany
- Prior art keywords
- dextromethorphan
- pain
- effective
- composition according
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 229910001467 sodium calcium phosphate Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 229960001462 sodium cyclamate Drugs 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid group Chemical group S(O)(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229950005250 tiquinamide Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/140,493 US4316888A (en) | 1980-04-15 | 1980-04-15 | Method and composition of reducing pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3115086A1 true DE3115086A1 (de) | 1982-04-15 |
Family
ID=22491480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19813115086 Withdrawn DE3115086A1 (de) | 1980-04-15 | 1981-04-14 | "dextromethorphan enthaltende pharamzeutische zusammensetzung und die verwendung von dextromethorphan zur schmerzbekaempfung" |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4316888A (enExample) |
| JP (1) | JPS56161328A (enExample) |
| AU (1) | AU547389B2 (enExample) |
| CA (1) | CA1174977A (enExample) |
| DE (1) | DE3115086A1 (enExample) |
| FR (1) | FR2480121A1 (enExample) |
| GB (1) | GB2074026B (enExample) |
| IT (1) | IT1195776B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0788359A4 (en) * | 1994-09-22 | 1998-08-19 | Richard Alan Smith | AGENTS FOR THE PRODUCTION OF MEDICINES FOR TREATING VARIOUS REFRACTORY DISORDER |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1194799A (en) * | 1981-12-10 | 1985-10-08 | Eric L. Nelson | Method and composition for reducing menstrual pain |
| EP0170680A4 (en) * | 1984-01-27 | 1987-06-29 | Baxter Travenol Lab | ISOTONIC MEDICAL COMPOSITIONS THAT ARE FINALLY STERILIZABLE. |
| US4694010A (en) * | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
| US4898860A (en) * | 1985-08-16 | 1990-02-06 | New York University | Anticonvulsant composition and method |
| WO1987004077A1 (en) * | 1986-01-03 | 1987-07-16 | The University Of Melbourne | Gastro-oesophageal reflux composition |
| IE58373B1 (en) * | 1986-06-18 | 1993-09-08 | Bloomfield Frederick Jacob | 5-Lipoxygenase pathway inhibitors |
| NZ230701A (en) * | 1988-09-20 | 1992-01-29 | Glaxo Group Ltd | Pharmaceutical compositions comprising ranitidine, alginic acid and a carbonate or bicarbonate |
| US5100898A (en) * | 1990-01-25 | 1992-03-31 | Richardson-Vicks Inc. | Antitussive liquid compositions containing dyclonine |
| US5229137A (en) * | 1992-05-06 | 1993-07-20 | Brigham And Women's Hospital, Inc. | Methods and pharmaceutical compositions for treating episodic heartburn |
| GR1002332B (el) * | 1992-05-21 | 1996-05-16 | Mcneil-Ppc Inc. | Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη. |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| USRE39300E1 (en) | 1993-01-28 | 2006-09-19 | Virginia Commonwealth University Medical College Of Virginia | Inhibiting the development of tolerance to and/or dependence on an addictive substance |
| US5352683A (en) * | 1993-03-05 | 1994-10-04 | Virginia Commonwealth University Medical College Of Virginia | Method for the treatment of chronic pain |
| US5834479A (en) * | 1993-03-05 | 1998-11-10 | Mayer; David J. | Method and composition for alleviating pain |
| CA2115792C (en) | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
| US5399354A (en) * | 1993-05-28 | 1995-03-21 | Mcneil-Ppc, Inc. | Process for making a hard-candy based oral pharmaceutical lozenge containing an antacid |
| JP3348230B2 (ja) * | 1995-03-03 | 2002-11-20 | アルゴス ファーマシューティカル コーポレーション | 尿失禁の治療用のデキシトルメトルファン又はデキシトルオルファンの使用 |
| US5840731A (en) * | 1995-08-02 | 1998-11-24 | Virginia Commonwealth University | Pain-alleviating drug composition and method for alleviating pain |
| US6197830B1 (en) * | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| JP3001440B2 (ja) * | 1996-11-25 | 2000-01-24 | 日本電気通信システム株式会社 | 仮想ｌａｎ方式 |
| US6207674B1 (en) | 1999-12-22 | 2001-03-27 | Richard A. Smith | Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants |
| WO2002100434A1 (en) * | 2001-06-07 | 2002-12-19 | The General Hospital Corporation | Treatment of neuropathic pain with n-methyl-d-aspartate (nmda) receptor antagonists |
| US20030175360A1 (en) * | 2002-02-22 | 2003-09-18 | Renzo Luzzatti | Symptomatic relief of gastrointestinal disorders |
| TWI326214B (en) * | 2002-07-17 | 2010-06-21 | Avanir Pharmaceuticals Inc | Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| US20040185032A1 (en) * | 2003-03-18 | 2004-09-23 | David Burrell | Compositions and methods for treating colic |
| JP2009525343A (ja) * | 2006-02-03 | 2009-07-09 | アバニール・ファーマシューティカルズ | 鬱病、不安および神経変性疾患を治療するためのデキストロメトルファンおよびキニジンを含む薬剤組成物 |
| EP3632916B1 (en) | 2007-05-01 | 2022-06-08 | Concert Pharmaceuticals Inc. | Morphinan compounds |
| DK3825306T3 (da) | 2007-05-01 | 2023-09-11 | Sun Pharmaceutical Ind Inc | Morphinanforbindelser |
| MX370608B (es) | 2007-05-01 | 2019-12-18 | Concert Pharmaceuticals Inc | Compuestos de morfinano. |
| JP5835865B2 (ja) * | 2008-09-04 | 2015-12-24 | 興和株式会社 | ロキソプロフェン含有医薬組成物 |
| EA023962B1 (ru) | 2008-09-19 | 2016-07-29 | Консерт Фармасьютикалз Инк. | Дейтерированные морфинановые соединения |
| US20100273822A1 (en) * | 2009-04-22 | 2010-10-28 | William Wayne Howard | Immediate release compositions and methods for delivering drug formulations using strong acid ion exchange resins |
| BE1018941A3 (nl) * | 2009-09-30 | 2011-11-08 | Cnh Belgium Nv | Een rechthoekige balenpers met een stuureenheid. |
| US11617728B2 (en) * | 2013-11-05 | 2023-04-04 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| EP3478664B1 (en) | 2016-07-04 | 2020-12-02 | Avanir Pharmaceuticals, Inc. | Methods for the synthesis of deuterated dextromethorphan |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2934472A (en) * | 1958-01-13 | 1960-04-26 | Dow Corning | Process for relieving human gas pains with methylpolysiloxane |
| US3108041A (en) * | 1960-05-11 | 1963-10-22 | Endo Lab | Antitussive compositions |
| US3085942A (en) * | 1960-12-28 | 1963-04-16 | Hoffmann La Roche | Antitussive compositions and preparation |
| US3140978A (en) * | 1961-11-02 | 1964-07-14 | Hoffmann La Roche | Pharmaceutical composition containing complex magnesium aluminum silicate |
| US3427379A (en) * | 1966-01-13 | 1969-02-11 | Hoffmann La Roche | Dextromethorphan and benzyl alcohol hard candy lozenges free from opaqueness and/or tiny entrapped air bubbles |
| US3767794A (en) * | 1969-11-21 | 1973-10-23 | Richardson Merrell Inc | Antifoam preparations and method of preparing same |
| US3919237A (en) * | 1972-07-07 | 1975-11-11 | Hoffmann La Roche | Preparation of isomorphinan derivative |
-
1980
- 1980-04-15 US US06/140,493 patent/US4316888A/en not_active Expired - Lifetime
-
1981
- 1981-03-10 GB GB8107444A patent/GB2074026B/en not_active Expired
- 1981-04-01 CA CA000374386A patent/CA1174977A/en not_active Expired
- 1981-04-07 AU AU69162/81A patent/AU547389B2/en not_active Ceased
- 1981-04-14 FR FR8107488A patent/FR2480121A1/fr active Granted
- 1981-04-14 DE DE19813115086 patent/DE3115086A1/de not_active Withdrawn
- 1981-04-15 IT IT21179/81A patent/IT1195776B/it active
- 1981-04-15 JP JP5570181A patent/JPS56161328A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0788359A4 (en) * | 1994-09-22 | 1998-08-19 | Richard Alan Smith | AGENTS FOR THE PRODUCTION OF MEDICINES FOR TREATING VARIOUS REFRACTORY DISORDER |
| EP1634597A1 (en) * | 1994-09-22 | 2006-03-15 | Richard Alan Smith | Compositions comprising dextromethorphan and quinidine or quinine for the treatment of emotional lability |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2074026B (en) | 1984-12-12 |
| CA1174977A (en) | 1984-09-25 |
| IT8121179A1 (it) | 1982-10-15 |
| AU6916281A (en) | 1981-10-22 |
| GB2074026A (en) | 1981-10-28 |
| IT8121179A0 (it) | 1981-04-15 |
| FR2480121B1 (enExample) | 1984-04-27 |
| IT1195776B (it) | 1988-10-27 |
| AU547389B2 (en) | 1985-10-17 |
| US4316888A (en) | 1982-02-23 |
| JPS56161328A (en) | 1981-12-11 |
| FR2480121A1 (fr) | 1981-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8141 | Disposal/no request for examination |