DE3111859C2 - Di-N↑6↑↑'↑,O↑3↑-desmethylistamycin A Verfahren zu dessen Herstellung und diese Verbindung enthaltende pharmazeutische Zubereitungen - Google Patents

Di-N↑6↑↑'↑,O↑3↑-desmethylistamycin A Verfahren zu dessen Herstellung und diese Verbindung enthaltende pharmazeutische Zubereitungen

Info

Publication number
DE3111859C2
DE3111859C2 DE3111859A DE3111859A DE3111859C2 DE 3111859 C2 DE3111859 C2 DE 3111859C2 DE 3111859 A DE3111859 A DE 3111859A DE 3111859 A DE3111859 A DE 3111859A DE 3111859 C2 DE3111859 C2 DE 3111859C2
Authority
DE
Germany
Prior art keywords
desmethylistamycin
compound
preparation
deep
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3111859A
Other languages
German (de)
English (en)
Other versions
DE3111859A1 (de
Inventor
Daishiro Tokyo Ikeda
Shinichi Yokohama Kanagawa Kondo
Hamao Tokyo Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of DE3111859A1 publication Critical patent/DE3111859A1/de
Application granted granted Critical
Publication of DE3111859C2 publication Critical patent/DE3111859C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3111859A 1980-03-28 1981-03-26 Di-N↑6↑↑'↑,O↑3↑-desmethylistamycin A Verfahren zu dessen Herstellung und diese Verbindung enthaltende pharmazeutische Zubereitungen Expired DE3111859C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3888980A JPS56138180A (en) 1980-03-28 1980-03-28 Di-n6',o3-demethylistamycin a and its preparation

Publications (2)

Publication Number Publication Date
DE3111859A1 DE3111859A1 (de) 1982-02-11
DE3111859C2 true DE3111859C2 (de) 1983-03-03

Family

ID=12537765

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3111859A Expired DE3111859C2 (de) 1980-03-28 1981-03-26 Di-N↑6↑↑'↑,O↑3↑-desmethylistamycin A Verfahren zu dessen Herstellung und diese Verbindung enthaltende pharmazeutische Zubereitungen

Country Status (7)

Country Link
US (1) US4474946A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS56138180A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1175817A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3111859C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2482107A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2073182B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (2) IT8109369A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS617284A (ja) * 1984-06-22 1986-01-13 Daicel Chem Ind Ltd 糖類アセチル誘導体の選択的脱アセチル化方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231924A (en) * 1976-09-23 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4312858A (en) * 1978-07-13 1982-01-26 Kowa Company, Ltd. Antibiotic KA-7038 and compositions containing same
SE447386B (sv) * 1978-10-18 1986-11-10 Kowa Co Aminoglykosider, komposition innehallande dem samt forfarande for framstellning av dem
US4330673A (en) * 1979-03-29 1982-05-18 Abbott Laboratories Process for producing 3-O-demethylaminoglycoside and novel 3-O-demethylfortimicin derivatives
US4282211A (en) * 1979-09-26 1981-08-04 Abbott Laboratories 1-Epi-2-deoxyfortimicin B and derivatives
US4251516A (en) * 1979-09-26 1981-02-17 Abbott Laboratories 2-Deoxy-3-O-Demethylfortimicins
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
JPS5772998A (en) * 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel appamycin derivative
JPS5775994A (en) * 1980-10-27 1982-05-12 Shionogi & Co Ltd Novel aprosamine derivative

Also Published As

Publication number Publication date
JPS56138180A (en) 1981-10-28
GB2073182B (en) 1983-09-21
FR2482107B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-02-10
IT8109369A1 (it) 1982-09-27
US4474946A (en) 1984-10-02
IT1167854B (it) 1987-05-20
FR2482107A1 (fr) 1981-11-13
IT8109369A0 (it) 1981-03-27
JPS6362513B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-12-02
DE3111859A1 (de) 1982-02-11
GB2073182A (en) 1981-10-14
CA1175817A (en) 1984-10-09

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Legal Events

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OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee