FR2482107A1 - Nouvel antibiotique aminoglycosidique derive de l'istamycine a, procede de preparation et compositions pharmaceutiques le renfermant - Google Patents

Nouvel antibiotique aminoglycosidique derive de l'istamycine a, procede de preparation et compositions pharmaceutiques le renfermant Download PDF

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Publication number
FR2482107A1
FR2482107A1 FR8106816A FR8106816A FR2482107A1 FR 2482107 A1 FR2482107 A1 FR 2482107A1 FR 8106816 A FR8106816 A FR 8106816A FR 8106816 A FR8106816 A FR 8106816A FR 2482107 A1 FR2482107 A1 FR 2482107A1
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FR
France
Prior art keywords
group
amino
compound
formula
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8106816A
Other languages
English (en)
French (fr)
Other versions
FR2482107B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Hamao Umezawa
Shinichi Kondo
Daishiro Ikeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2482107A1 publication Critical patent/FR2482107A1/fr
Application granted granted Critical
Publication of FR2482107B1 publication Critical patent/FR2482107B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8106816A 1980-03-28 1981-03-27 Nouvel antibiotique aminoglycosidique derive de l'istamycine a, procede de preparation et compositions pharmaceutiques le renfermant Granted FR2482107A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3888980A JPS56138180A (en) 1980-03-28 1980-03-28 Di-n6',o3-demethylistamycin a and its preparation

Publications (2)

Publication Number Publication Date
FR2482107A1 true FR2482107A1 (fr) 1981-11-13
FR2482107B1 FR2482107B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-02-10

Family

ID=12537765

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8106816A Granted FR2482107A1 (fr) 1980-03-28 1981-03-27 Nouvel antibiotique aminoglycosidique derive de l'istamycine a, procede de preparation et compositions pharmaceutiques le renfermant

Country Status (7)

Country Link
US (1) US4474946A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS56138180A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1175817A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3111859C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2482107A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2073182B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (2) IT8109369A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS617284A (ja) * 1984-06-22 1986-01-13 Daicel Chem Ind Ltd 糖類アセチル誘導体の選択的脱アセチル化方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430951A1 (fr) * 1978-07-13 1980-02-08 Kowa Co Antibiotiques, leur preparation et culture de preparation
FR2439206A1 (fr) * 1978-10-18 1980-05-16 Kowa Co Aminoheterosides, leur preparation et medicament contenant ces substances

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231924A (en) * 1976-09-23 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4330673A (en) * 1979-03-29 1982-05-18 Abbott Laboratories Process for producing 3-O-demethylaminoglycoside and novel 3-O-demethylfortimicin derivatives
US4251516A (en) * 1979-09-26 1981-02-17 Abbott Laboratories 2-Deoxy-3-O-Demethylfortimicins
US4282211A (en) * 1979-09-26 1981-08-04 Abbott Laboratories 1-Epi-2-deoxyfortimicin B and derivatives
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
JPS5772998A (en) * 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel appamycin derivative
JPS5775994A (en) * 1980-10-27 1982-05-12 Shionogi & Co Ltd Novel aprosamine derivative

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430951A1 (fr) * 1978-07-13 1980-02-08 Kowa Co Antibiotiques, leur preparation et culture de preparation
FR2439206A1 (fr) * 1978-10-18 1980-05-16 Kowa Co Aminoheterosides, leur preparation et medicament contenant ces substances

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/79 *
EXBK/80 *

Also Published As

Publication number Publication date
IT8109369A1 (it) 1982-09-27
US4474946A (en) 1984-10-02
CA1175817A (en) 1984-10-09
FR2482107B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-02-10
GB2073182A (en) 1981-10-14
JPS6362513B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-12-02
DE3111859A1 (de) 1982-02-11
DE3111859C2 (de) 1983-03-03
IT8109369A0 (it) 1981-03-27
JPS56138180A (en) 1981-10-28
IT1167854B (it) 1987-05-20
GB2073182B (en) 1983-09-21

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