DE3048883A1 - Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung - Google Patents

Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung

Info

Publication number
DE3048883A1
DE3048883A1 DE19803048883 DE3048883A DE3048883A1 DE 3048883 A1 DE3048883 A1 DE 3048883A1 DE 19803048883 DE19803048883 DE 19803048883 DE 3048883 A DE3048883 A DE 3048883A DE 3048883 A1 DE3048883 A1 DE 3048883A1
Authority
DE
Germany
Prior art keywords
latex particles
water
hydrophilic latex
hydrophilic
emulsion polymerization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19803048883
Other languages
German (de)
English (en)
Inventor
Manfred Dr.rer.nat. 8134 Pöcking Baier
Hans-Georg Dr.Rer.Nat. 8132 Tutzing Batz
Karel Dr.-Ing. 150 00 Prag Bouchal
Jaroslav Prof. Dr.-Ing. 160 00 Prag Kalal
Jaroslav Prof. Dr.Ing. 160 00 Praha Kalal
Frantisek Dr.-Ing. 273 43 Hrebec Svec
Paul Dr.phil. 8033 Planegg Tanswell
geb. Hrubá Eva 147 00 Praha Zurkova
geb. Hrubá Eva Dr.-Ing. 147 00 Praha Zurkova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tschechoslowakische Akademie Der Wissenschaften 11142 Praha
Czech Academy of Sciences CAS
Roche Diagnostics GmbH
Original Assignee
Tschechoslowakische Akademie Der Wissenschaften 11142 Praha
Czech Academy of Sciences CAS
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tschechoslowakische Akademie Der Wissenschaften 11142 Praha, Czech Academy of Sciences CAS, Boehringer Mannheim GmbH filed Critical Tschechoslowakische Akademie Der Wissenschaften 11142 Praha
Priority to DE19803048883 priority Critical patent/DE3048883A1/de
Priority to EP81108886A priority patent/EP0054685B1/de
Priority to AT81108886T priority patent/ATE20670T1/de
Priority to DE8181108886T priority patent/DE3174918D1/de
Priority to US06/331,114 priority patent/US4415700A/en
Priority to JP56207275A priority patent/JPS6043361B2/ja
Publication of DE3048883A1 publication Critical patent/DE3048883A1/de
Priority to JP58230705A priority patent/JPS59116548A/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/22—Emulsion polymerisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymerisation Methods In General (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE19803048883 1980-12-23 1980-12-23 Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung Ceased DE3048883A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19803048883 DE3048883A1 (de) 1980-12-23 1980-12-23 Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung
EP81108886A EP0054685B1 (de) 1980-12-23 1981-10-24 Hydrophile Latexpartikel, Verfahren zu deren Herstellung und deren Verwendung
AT81108886T ATE20670T1 (de) 1980-12-23 1981-10-24 Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung.
DE8181108886T DE3174918D1 (en) 1980-12-23 1981-10-24 Hydrophilic latex particles, process for their preparation and their use
US06/331,114 US4415700A (en) 1980-12-23 1981-12-16 Hydrophilic latex particles and use thereof
JP56207275A JPS6043361B2 (ja) 1980-12-23 1981-12-23 親水性ラテックス粒子の製法
JP58230705A JPS59116548A (ja) 1980-12-23 1983-12-08 親水性ラテツクス粒子を含有する診断薬

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803048883 DE3048883A1 (de) 1980-12-23 1980-12-23 Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
DE3048883A1 true DE3048883A1 (de) 1982-07-15

Family

ID=6120185

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803048883 Ceased DE3048883A1 (de) 1980-12-23 1980-12-23 Hydrophile latexpartikel, verfahren zu deren herstellung und deren verwendung

Country Status (2)

Country Link
JP (2) JPS6043361B2 (ja)
DE (1) DE3048883A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427441A1 (de) * 1983-06-10 1986-02-06 Japan Exlan Co. Ltd., Osaka Kornaehnliches polymer und verfahren zu dessen herstellung
DE3530312A1 (de) * 1985-08-24 1987-02-26 Guenther Dr Sawatzki Traeger fuer die photometrische immunspezifische bestimmung von antigenen oder antikoerpern, verfahren zu ihrer herstellung und verwendung
WO2005049093A1 (en) * 2003-11-03 2005-06-02 Istituto Superiore Di Sanita Use of microparticles for antigen delivery

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58185604A (ja) * 1982-04-26 1983-10-29 Tokuyama Soda Co Ltd ポリメタクリル酸グリシジルラテツクスの製造方法
JPS59182804A (ja) * 1983-04-01 1984-10-17 Toray Ind Inc 反応性微粒子およびその製造法
JPS59204601A (ja) * 1983-05-09 1984-11-20 Unitika Ltd 生理活性を有する成形体の製造方法
DE3318184A1 (de) * 1983-05-19 1984-11-22 Boehringer Mannheim Gmbh, 6800 Mannheim Traeger zur beschichtung mit immunologisch aktivem material
JPS59219380A (ja) * 1983-05-27 1984-12-10 Nippon Mektron Ltd 撥水撥油剤エマルジヨンの製造法
JPH0713641B2 (ja) * 1984-05-07 1995-02-15 株式会社トクヤマ 診断用試薬の製造方法
US7465765B2 (en) * 2004-09-27 2008-12-16 Hewlett-Packard Development Company, L.P. Latex particulates with epoxide functional groups
JP4993081B2 (ja) * 2007-02-28 2012-08-08 Ｊｓｒ株式会社 蛋白質固定化磁性粒子およびその製造方法
WO2008111599A1 (ja) * 2007-03-12 2008-09-18 Jsr Corporation 生体関連物質の検出方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2841033A1 (de) * 1978-09-21 1980-04-03 Bayer Ag Verfahren zur herstellung waessriger polymerisatdispersionen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH628738A5 (de) * 1977-08-03 1982-03-15 Hoffmann La Roche Immunologisches diagnose-reagenz.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2841033A1 (de) * 1978-09-21 1980-04-03 Bayer Ag Verfahren zur herstellung waessriger polymerisatdispersionen

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427441A1 (de) * 1983-06-10 1986-02-06 Japan Exlan Co. Ltd., Osaka Kornaehnliches polymer und verfahren zu dessen herstellung
DE3530312A1 (de) * 1985-08-24 1987-02-26 Guenther Dr Sawatzki Traeger fuer die photometrische immunspezifische bestimmung von antigenen oder antikoerpern, verfahren zu ihrer herstellung und verwendung
WO2005049093A1 (en) * 2003-11-03 2005-06-02 Istituto Superiore Di Sanita Use of microparticles for antigen delivery

Also Published As

Publication number Publication date
JPS57135801A (en) 1982-08-21
JPS59116548A (ja) 1984-07-05
JPH028271B2 (ja) 1990-02-23
JPS6043361B2 (ja) 1985-09-27

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection