DE3045288C2 - - Google Patents

Info

Publication number
DE3045288C2
DE3045288C2 DE3045288T DE3045288T DE3045288C2 DE 3045288 C2 DE3045288 C2 DE 3045288C2 DE 3045288 T DE3045288 T DE 3045288T DE 3045288 T DE3045288 T DE 3045288T DE 3045288 C2 DE3045288 C2 DE 3045288C2
Authority
DE
Germany
Prior art keywords
vitamin
hydroxy
keto
acetyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3045288T
Other languages
German (de)
English (en)
Other versions
DE3045288T1 (de
Inventor
Hector F. Deluca
Heinrich K. Madison Wis. Us Schnoes
Joseph L. Dallas Tex. Us Napoli
Mary A. Madison Wis. Us Fivizzani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE3045288T1 publication Critical patent/DE3045288T1/de
Application granted granted Critical
Publication of DE3045288C2 publication Critical patent/DE3045288C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE803045288T 1979-05-21 1980-04-29 1 alpha -hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same Granted DE3045288T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/041,081 US4264513A (en) 1979-05-21 1979-05-21 1α-hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same
PCT/US1980/000495 WO1980002502A1 (en) 1979-05-21 1980-04-29 1 alpha -hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same

Publications (2)

Publication Number Publication Date
DE3045288T1 DE3045288T1 (de) 1982-02-18
DE3045288C2 true DE3045288C2 (en:Method) 1989-07-13

Family

ID=21914622

Family Applications (1)

Application Number Title Priority Date Filing Date
DE803045288T Granted DE3045288T1 (de) 1979-05-21 1980-04-29 1 alpha -hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same

Country Status (9)

Country Link
US (1) US4264513A (en:Method)
JP (3) JPS56500611A (en:Method)
CH (2) CH653004A5 (en:Method)
DE (1) DE3045288T1 (en:Method)
FR (1) FR2457284B1 (en:Method)
GB (2) GB2075982B (en:Method)
IE (1) IE49811B1 (en:Method)
IL (1) IL60088A (en:Method)
WO (1) WO1980002502A1 (en:Method)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE899612A (fr) * 1983-05-09 1984-08-31 Wisconsin Alumni Res Found Derives 1 alpha, 25-dihydroxiles de la vitamine d2 et produits intermediaires pour leur preparation et compositions pharmaceutiques renfermant ces derives.
DE3590020T1 (de) * 1984-01-30 1986-01-23 Wisconsin Alumni Research Foundation, Madison, Wis. In der Seitenkette ungesättigte 1-Hydroxyvitamin D-Verbindungen
US5472434A (en) * 1993-05-14 1995-12-05 Akzo N.V. Spike retainer system
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2838092A1 (de) * 1977-09-07 1979-03-08 Teijin Ltd 1 alpha -hydroxy-24-oxovitamin d tief 3 , verfahren zu seiner herstellung, dabei verwendete vorlaeufer und verwendung von 1 alpha -hydroxy-24-oxovitamin d tief 3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4105660A (en) * 1977-06-29 1978-08-08 Merck & Co., Inc. Preparation of 3β-hydroxy-27-norcholest-5,7-dien-25-one
US4145346A (en) * 1977-10-03 1979-03-20 Merck & Co., Inc. Preparation of 3β-hydroxy-27-norcholest-5-ene-25-one and intermediates thereof
US4206131A (en) * 1978-06-19 1980-06-03 The Upjohn Company Compounds and process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2838092A1 (de) * 1977-09-07 1979-03-08 Teijin Ltd 1 alpha -hydroxy-24-oxovitamin d tief 3 , verfahren zu seiner herstellung, dabei verwendete vorlaeufer und verwendung von 1 alpha -hydroxy-24-oxovitamin d tief 3

Also Published As

Publication number Publication date
GB2052508B (en) 1983-06-29
JPS6485961A (en) 1989-03-30
WO1980002502A1 (en) 1980-11-27
GB2052508A (en) 1981-01-28
IE49811B1 (en) 1985-12-25
JPH0319240B2 (en:Method) 1991-03-14
FR2457284A1 (fr) 1980-12-19
IE801057L (en) 1980-11-21
JPH0146505B2 (en:Method) 1989-10-09
CH653004A5 (de) 1985-12-13
US4264513A (en) 1981-04-28
IL60088A (en) 1984-07-31
JPS56500611A (en:Method) 1981-05-07
JPH02223592A (ja) 1990-09-05
CH653344A5 (de) 1985-12-31
GB2075982A (en) 1981-11-25
GB2075982B (en) 1983-06-02
IL60088A0 (en) 1980-07-31
FR2457284B1 (fr) 1985-12-27
DE3045288T1 (de) 1982-02-18

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Legal Events

Date Code Title Description
D2 Grant after examination
8364 No opposition during term of opposition