DE3007685A1 - Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE3007685A1
DE3007685A1 DE19803007685 DE3007685A DE3007685A1 DE 3007685 A1 DE3007685 A1 DE 3007685A1 DE 19803007685 DE19803007685 DE 19803007685 DE 3007685 A DE3007685 A DE 3007685A DE 3007685 A1 DE3007685 A1 DE 3007685A1
Authority
DE
Germany
Prior art keywords
group
general formula
hydrogen atom
methyl
general formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19803007685
Other languages
German (de)
English (en)
Inventor
Hanns Dr. 7950 Biberach Goeth
Uwe Dr. 7951 Ummendorf Lechner
Roland Dipl.-Chem. Dr. 7950 Biberach Maier
Wolfgang Dipl.-Chem. Dr. 7951 Laupertshausen Reuter
Bernd Dipl.-Chem. Dr. Wetzel
Eberhard Dipl.-Chem. Dr. 7950 Biberach Woitun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to DE19803007685 priority Critical patent/DE3007685A1/de
Priority to AT81101107T priority patent/ATE5408T1/de
Priority to DE8181101107T priority patent/DE3161462D1/de
Priority to EP81101107A priority patent/EP0035161B1/de
Priority to GR64234A priority patent/GR73684B/el
Priority to US06/237,066 priority patent/US4370327A/en
Priority to DK87281A priority patent/DK87281A/da
Priority to ES499864A priority patent/ES499864A0/es
Priority to HU81493A priority patent/HU184390B/hu
Priority to PT72582A priority patent/PT72582B/pt
Priority to FI810618A priority patent/FI810618A7/fi
Priority to NZ196370A priority patent/NZ196370A/en
Priority to AU67926/81A priority patent/AU541190B2/en
Priority to CA000372017A priority patent/CA1150726A/en
Priority to IL62226A priority patent/IL62226A/xx
Priority to JP2830581A priority patent/JPS56135491A/ja
Priority to PH25277A priority patent/PH17062A/en
Priority to NO810678A priority patent/NO810678L/no
Priority to ZA00811316A priority patent/ZA811316B/xx
Publication of DE3007685A1 publication Critical patent/DE3007685A1/de
Priority to ES509555A priority patent/ES509555A0/es
Priority to ES509554A priority patent/ES8307821A1/es
Priority to ES509553A priority patent/ES509553A0/es
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
DE19803007685 1980-02-29 1980-02-29 Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Withdrawn DE3007685A1 (de)

Priority Applications (22)

Application Number Priority Date Filing Date Title
DE19803007685 DE3007685A1 (de) 1980-02-29 1980-02-29 Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AT81101107T ATE5408T1 (de) 1980-02-29 1981-02-17 Cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DE8181101107T DE3161462D1 (en) 1980-02-29 1981-02-17 Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds
EP81101107A EP0035161B1 (de) 1980-02-29 1981-02-17 Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
GR64234A GR73684B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-02-29 1981-02-20
US06/237,066 US4370327A (en) 1980-02-29 1981-02-23 Cephalosporins and pharmaceutical compositions
DK87281A DK87281A (da) 1980-02-29 1981-02-26 Cephalosporiner fremgangsmaade til deres fremstilling samt deres anvendelse
NZ196370A NZ196370A (en) 1980-02-29 1981-02-27 Cephalosporins and pharmaceutical and veterinary compositions containing them
PH25277A PH17062A (en) 1980-02-29 1981-02-27 Cephalosporins and pharmaceutical compositions
PT72582A PT72582B (pt) 1980-02-29 1981-02-27 Neue cephalosporine verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FI810618A FI810618A7 (fi) 1980-02-29 1981-02-27 Uudet kefalosporiinit, niiden valmistusmenetelmä ja näitä yhdisteitä sisältävät lääkeaineet.
ES499864A ES499864A0 (es) 1980-02-29 1981-02-27 Procedimiento para la preparacion de nuevas cefalosporinas
AU67926/81A AU541190B2 (en) 1980-02-29 1981-02-27 Cephalosporin derivatives
CA000372017A CA1150726A (en) 1980-02-29 1981-02-27 Cephalosporins, processes for the preparation and pharmaceuticals containing these compounds
IL62226A IL62226A (en) 1980-02-29 1981-02-27 ((substituted pyrimidinyl-ureido)-(2,3-dihydro-2-imino-4-thiazolyl))acetamido-cephalosporins,their preparation and pharmaceutical compositions containing them
JP2830581A JPS56135491A (en) 1980-02-29 1981-02-27 Cephalosporin
HU81493A HU184390B (en) 1980-02-29 1981-02-27 Process for producing 7-figural bracket-square bracke-bracket-4-hydroxy-5-pyrimidinyl-bracket closed-ureido-square bracket closed-bracket-2,3-dihydro-2-imino-4-triazolyl-aracket closed-acetamido-figural bracket closed-3-methyl-ceph-3-eme-4-carboxylic acid derivatives
NO810678A NO810678L (no) 1980-02-29 1981-02-27 Analogifremgangsmaate for fremstilling av farmakologisk aktive cefalosporinderivater
ZA00811316A ZA811316B (en) 1980-02-29 1981-02-27 Cephalosporins,processes for their preparation,and pharmaceutical compositions containing these
ES509555A ES509555A0 (es) 1980-02-29 1982-02-12 "procedimiento para la preparacion de nuevas cefalosporinas".
ES509554A ES8307821A1 (es) 1980-02-29 1982-02-12 "procedimiento para la preparacion de nuevas cefalosporinas".
ES509553A ES509553A0 (es) 1980-02-29 1982-02-12 "procedimiento para la preparacion de nuevas cefalosporinas".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803007685 DE3007685A1 (de) 1980-02-29 1980-02-29 Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DE3007685A1 true DE3007685A1 (de) 1981-10-01

Family

ID=6095889

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19803007685 Withdrawn DE3007685A1 (de) 1980-02-29 1980-02-29 Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE8181101107T Expired DE3161462D1 (en) 1980-02-29 1981-02-17 Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8181101107T Expired DE3161462D1 (en) 1980-02-29 1981-02-17 Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds

Country Status (18)

Country Link
US (1) US4370327A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0035161B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS56135491A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE5408T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU541190B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1150726A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3007685A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK87281A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (4) ES499864A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI810618A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR73684B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU184390B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL62226A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO810678L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ196370A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH17062A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT72582B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA811316B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3038501A1 (de) * 1980-10-11 1982-05-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel
EP0053276A3 (de) * 1980-12-02 1983-08-03 Dr. Karl Thomae GmbH Neue Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3047082A1 (de) * 1980-12-13 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
US4758557A (en) * 1985-06-26 1988-07-19 Meiji Seika Kaisha, Ltd. Cephalosporin derivatives and bactericides containing the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5919114B2 (ja) * 1975-08-25 1984-05-02 武田薬品工業株式会社 セフアロスポリンの製造法
US4063019A (en) * 1976-03-30 1977-12-13 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives
JPS5344585A (en) * 1976-10-02 1978-04-21 Meiji Seika Kaisha Ltd Cephalosporin derivatives and their preparation
JPS54117494A (en) * 1978-03-03 1979-09-12 Takeda Chem Ind Ltd Cephalosporin compound and its preparation
ZA792724B (en) 1978-06-16 1980-08-27 Squibb & Sons Inc Iminothiazolyl ureido cephalosporins
DE2828261A1 (de) * 1978-06-28 1980-01-10 Thomae Gmbh Dr K Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS6058239B2 (ja) 1978-07-20 1985-12-19 山之内製薬株式会社 新規セフアロスポリン誘導体
DE2924948A1 (de) * 1979-06-21 1981-01-22 Thomae Gmbh Dr K Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DK87281A (da) 1981-08-30
ES8303425A1 (es) 1983-02-01
PT72582A (pt) 1981-03-01
ZA811316B (en) 1982-11-24
EP0035161B1 (de) 1983-11-23
AU6792681A (en) 1981-09-03
PT72582B (pt) 1982-10-21
IL62226A0 (en) 1981-03-31
ES509554A0 (es) 1983-07-16
PH17062A (en) 1984-05-24
ES8307258A1 (es) 1983-06-16
GR73684B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-04-02
IL62226A (en) 1984-03-30
ES8307821A1 (es) 1983-07-16
FI810618L (fi) 1981-08-30
FI810618A7 (fi) 1981-08-30
US4370327A (en) 1983-01-25
EP0035161A3 (en) 1981-11-04
ES8307257A1 (es) 1983-06-16
CA1150726A (en) 1983-07-26
DE3161462D1 (en) 1983-12-29
ES509553A0 (es) 1983-06-16
ATE5408T1 (de) 1983-12-15
AU541190B2 (en) 1984-12-20
EP0035161A2 (de) 1981-09-09
HU184390B (en) 1984-08-28
ES499864A0 (es) 1983-02-01
NO810678L (no) 1981-08-31
ES509555A0 (es) 1983-06-16
NZ196370A (en) 1984-03-30
JPS56135491A (en) 1981-10-22

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Legal Events

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8139 Disposal/non-payment of the annual fee