DE2931792A1 - Antifibrotische substanz p-1894b, verfahren zu ihrer herstellung und sie enthaltende arzneimittel - Google Patents

Antifibrotische substanz p-1894b, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Info

Publication number
DE2931792A1
DE2931792A1 DE19792931792 DE2931792A DE2931792A1 DE 2931792 A1 DE2931792 A1 DE 2931792A1 DE 19792931792 DE19792931792 DE 19792931792 DE 2931792 A DE2931792 A DE 2931792A DE 2931792 A1 DE2931792 A1 DE 2931792A1
Authority
DE
Germany
Prior art keywords
cologne
streptomyces
substance
culture
microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19792931792
Other languages
German (de)
English (en)
Other versions
DE2931792C2 (enExample
Inventor
Tsuneo Kanamaru
Kazuhiko Ohta
Hisayoshi Okazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE2931792A1 publication Critical patent/DE2931792A1/de
Application granted granted Critical
Publication of DE2931792C2 publication Critical patent/DE2931792C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DE19792931792 1978-08-07 1979-08-04 Antifibrotische substanz p-1894b, verfahren zu ihrer herstellung und sie enthaltende arzneimittel Granted DE2931792A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9655378A JPS5522650A (en) 1978-08-07 1978-08-07 Novel bioactive substance

Publications (2)

Publication Number Publication Date
DE2931792A1 true DE2931792A1 (de) 1980-02-21
DE2931792C2 DE2931792C2 (enExample) 1987-11-12

Family

ID=14168253

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2954566A Expired DE2954566C2 (enExample) 1978-08-07 1979-08-04
DE19792931792 Granted DE2931792A1 (de) 1978-08-07 1979-08-04 Antifibrotische substanz p-1894b, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2954566A Expired DE2954566C2 (enExample) 1978-08-07 1979-08-04

Country Status (5)

Country Link
US (1) US4260599A (enExample)
JP (1) JPS5522650A (enExample)
DE (2) DE2954566C2 (enExample)
FR (1) FR2433026A1 (enExample)
GB (1) GB2028132B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186869A1 (en) * 1990-05-14 2003-10-02 George Poiani Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US5958300A (en) * 1998-02-06 1999-09-28 Genzyme Corporation Composition for patient sample preparation
CN103215281B (zh) * 2013-04-03 2014-06-25 中国科学院南海海洋研究所 一种格瑞克霉素和p-1894b的生物合成基因簇及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914158A (en) * 1973-06-06 1975-10-21 Merck & Co Inc Antibiotic production

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
Anal. Biochem., 1975, 331-340 *
Arch. Biochem. Biophys., 1976, 382 *
Biochim. Biophys. Acta, 1967, 460 *
Intern. Journal of Systematic Bacteriology, 1966, 313-340 *
Internal Medicine, 1978, 724 *
J. Biol. Chem., 1951, 265-275 *
J. Biol. Chem., 1967, 4007 *
Japanese Pharmakopeia, 9. Aufl. *
Methods in Enzymology, XVIIB, 1979, 306 *
Qual. Biochem., 1966, 384-394 *
The Journal of Antibiotics, 1960, 321-326, 1964, 156-160, 1968, 91-97, 1977, 908-916 *

Also Published As

Publication number Publication date
DE2931792C2 (enExample) 1987-11-12
US4260599A (en) 1981-04-07
GB2028132A (en) 1980-03-05
DE2954566C2 (enExample) 1989-10-05
FR2433026B1 (enExample) 1983-04-29
FR2433026A1 (fr) 1980-03-07
GB2028132B (en) 1983-04-27
JPS6111206B2 (enExample) 1986-04-01
JPS5522650A (en) 1980-02-18

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