DE2917244C2 - 1-[[2-(2,4-Dichlorphenyl)-2-benzyloxy]-äthyl]-imidazole, Verfahren zu deren Herstellung sowie solche enthaltende Arzneimittel - Google Patents

1-[[2-(2,4-Dichlorphenyl)-2-benzyloxy]-äthyl]-imidazole, Verfahren zu deren Herstellung sowie solche enthaltende Arzneimittel

Info

Publication number
DE2917244C2
DE2917244C2 DE2917244A DE2917244A DE2917244C2 DE 2917244 C2 DE2917244 C2 DE 2917244C2 DE 2917244 A DE2917244 A DE 2917244A DE 2917244 A DE2917244 A DE 2917244A DE 2917244 C2 DE2917244 C2 DE 2917244C2
Authority
DE
Germany
Prior art keywords
dichlorophenyl
ethyl
benzyloxy
imidazole
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2917244A
Other languages
German (de)
English (en)
Other versions
DE2917244A1 (de
Inventor
Elena Prof. Massarani
Dante Prof. Nardi
Alberto Dr. Mailand/Milano Tajana
Mario Dr.rer.nat. Bresso Mailand/Milano Veronese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati Sa Chemical And Pharmaceutical Co Chiasso Ch
Original Assignee
Recordati Sa Chemical And Pharmaceutical Co Chiasso Ch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Sa Chemical And Pharmaceutical Co Chiasso Ch filed Critical Recordati Sa Chemical And Pharmaceutical Co Chiasso Ch
Publication of DE2917244A1 publication Critical patent/DE2917244A1/de
Application granted granted Critical
Publication of DE2917244C2 publication Critical patent/DE2917244C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE2917244A 1978-05-18 1979-04-27 1-[[2-(2,4-Dichlorphenyl)-2-benzyloxy]-äthyl]-imidazole, Verfahren zu deren Herstellung sowie solche enthaltende Arzneimittel Expired DE2917244C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (it) 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi

Publications (2)

Publication Number Publication Date
DE2917244A1 DE2917244A1 (de) 1979-11-22
DE2917244C2 true DE2917244C2 (de) 1985-09-05

Family

ID=11208025

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2917244A Expired DE2917244C2 (de) 1978-05-18 1979-04-27 1-[[2-(2,4-Dichlorphenyl)-2-benzyloxy]-äthyl]-imidazole, Verfahren zu deren Herstellung sowie solche enthaltende Arzneimittel

Country Status (29)

Country Link
JP (1) JPS605592B2 (fr)
AR (1) AR219596A1 (fr)
AT (1) AT372950B (fr)
AU (1) AU523053B2 (fr)
CA (1) CA1115718A (fr)
CH (1) CH639075A5 (fr)
DD (1) DD143608A5 (fr)
DE (1) DE2917244C2 (fr)
DK (1) DK153838C (fr)
EG (1) EG14345A (fr)
ES (1) ES480552A1 (fr)
FI (1) FI71309C (fr)
FR (1) FR2426047A1 (fr)
GB (1) GB2025395B (fr)
GR (1) GR68396B (fr)
HU (1) HU182565B (fr)
IE (1) IE48372B1 (fr)
IL (1) IL57245A (fr)
IT (1) IT1096361B (fr)
MX (1) MX5927E (fr)
NL (2) NL189255C (fr)
NO (1) NO152840C (fr)
NZ (1) NZ190412A (fr)
PH (1) PH14782A (fr)
PT (1) PT69537A (fr)
SE (1) SE444812B (fr)
SU (1) SU816399A3 (fr)
YU (1) YU112279A (fr)
ZA (1) ZA792015B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1155853A (fr) * 1980-06-06 1983-10-25 Joseph A. Martin Derives d'imidazole, et leur preparation
FR2541114B1 (fr) * 1983-02-23 1986-04-11 Sanofi Sa Compositions pharmaceutiques antifongiques utilisables par voie orale contenant de l'omoconazole
DK79184A (da) * 1983-02-23 1984-08-24 Sanofi Sa Fungicide farmaceutiske midler indeholdende et imidazolderivat
CA1250586A (fr) * 1984-02-02 1989-02-28 Manuel Raga Derives de 1h-imidazole et procede de production
DE3413365A1 (de) * 1984-04-09 1985-12-19 Merz + Co GmbH & Co, 6000 Frankfurt Substituierte phenylethylderivate, verfahren zu ihrer herstellung und pharmazeutische mittel
IT1200422B (it) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog Composto con attivita' antimicrobia,sua preparazione e composizioni farmaceutiche che lo contengono
ES2249992B1 (es) * 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Un procedimiento para fabricar compuestos enantiomericos del imidazol.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Also Published As

Publication number Publication date
MX5927E (es) 1984-08-29
SE444812B (sv) 1986-05-12
IL57245A (en) 1983-02-23
SU816399A3 (ru) 1981-03-23
YU112279A (en) 1983-01-21
IL57245A0 (en) 1979-09-30
IT1096361B (it) 1985-08-26
IE790958L (en) 1979-11-18
ES480552A1 (es) 1980-04-01
FR2426047B1 (fr) 1982-11-05
AT372950B (de) 1983-11-25
JPS54151974A (en) 1979-11-29
GR68396B (fr) 1981-12-29
FI791543A (fi) 1979-11-19
ZA792015B (en) 1980-04-30
HU182565B (en) 1984-02-28
NZ190412A (en) 1981-03-16
NL189255C (nl) 1993-02-16
NO791599L (no) 1979-11-20
JPS605592B2 (ja) 1985-02-12
FR2426047A1 (fr) 1979-12-14
FI71309B (fi) 1986-09-09
GB2025395A (en) 1980-01-23
PH14782A (en) 1981-12-09
DK153838B (da) 1988-09-12
FI71309C (fi) 1986-12-19
NL930014I1 (nl) 1993-05-03
GB2025395B (en) 1982-07-28
AR219596A1 (es) 1980-08-29
ATA345079A (de) 1983-04-15
DD143608A5 (de) 1980-09-03
IT7823546A0 (it) 1978-05-18
PT69537A (fr) 1979-05-01
IE48372B1 (en) 1984-12-26
NL930014I2 (nl) 1993-09-16
EG14345A (en) 1983-09-30
CH639075A5 (fr) 1983-10-31
DK153838C (da) 1989-01-30
DK196579A (da) 1979-11-19
NO152840C (no) 1985-11-27
SE7904319L (sv) 1979-11-19
NO152840B (no) 1985-08-19
NL7903872A (nl) 1979-11-20
CA1115718A (fr) 1982-01-05
DE2917244A1 (de) 1979-11-22
AU4714979A (en) 1979-11-22
AU523053B2 (en) 1982-07-08

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition