IE790958L - Ó-imidazolyldibenzylether derivatives - Google Patents

Ó-imidazolyldibenzylether derivatives

Info

Publication number
IE790958L
IE790958L IE790958A IE95879A IE790958L IE 790958 L IE790958 L IE 790958L IE 790958 A IE790958 A IE 790958A IE 95879 A IE95879 A IE 95879A IE 790958 L IE790958 L IE 790958L
Authority
IE
Ireland
Prior art keywords
phenylthio
bromomethyl
chloromethyl
biphenyl
benzene
Prior art date
Application number
IE790958A
Other versions
IE48372B1 (en
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of IE790958L publication Critical patent/IE790958L/en
Publication of IE48372B1 publication Critical patent/IE48372B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

Novel compounds I and their acid addition salts <IMAGE> in which R is phenyl or phenylthio show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'- dichlorophenyl)-2-(N-imidazolyl- methyl)-ethanol with 4-chloromethyl- biphenyl, 4-bromomethyl-biphenyl, 1- phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide. [GB2025395A]
IE958/79A 1978-05-18 1979-08-08 Therapeutically active imidazolylmethyl-substituted dibenzyl ethers IE48372B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (en) 1978-05-18 1978-05-18 THERAPEUTICALLY ACTIVE REPLACED BONDS

Publications (2)

Publication Number Publication Date
IE790958L true IE790958L (en) 1979-11-18
IE48372B1 IE48372B1 (en) 1984-12-26

Family

ID=11208025

Family Applications (1)

Application Number Title Priority Date Filing Date
IE958/79A IE48372B1 (en) 1978-05-18 1979-08-08 Therapeutically active imidazolylmethyl-substituted dibenzyl ethers

Country Status (29)

Country Link
JP (1) JPS605592B2 (en)
AR (1) AR219596A1 (en)
AT (1) AT372950B (en)
AU (1) AU523053B2 (en)
CA (1) CA1115718A (en)
CH (1) CH639075A5 (en)
DD (1) DD143608A5 (en)
DE (1) DE2917244C2 (en)
DK (1) DK153838C (en)
EG (1) EG14345A (en)
ES (1) ES480552A1 (en)
FI (1) FI71309C (en)
FR (1) FR2426047A1 (en)
GB (1) GB2025395B (en)
GR (1) GR68396B (en)
HU (1) HU182565B (en)
IE (1) IE48372B1 (en)
IL (1) IL57245A (en)
IT (1) IT1096361B (en)
MX (1) MX5927E (en)
NL (2) NL189255C (en)
NO (1) NO152840C (en)
NZ (1) NZ190412A (en)
PH (1) PH14782A (en)
PT (1) PT69537A (en)
SE (1) SE444812B (en)
SU (1) SU816399A3 (en)
YU (1) YU112279A (en)
ZA (1) ZA792015B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1155853A (en) * 1980-06-06 1983-10-25 Joseph A. Martin Imidazole derivatives and preparation thereof
EP0117811A3 (en) * 1983-02-23 1987-06-03 Sanofi S.A. Fungicidal pharmaceutical compositions for oral administration
FR2541114B1 (en) * 1983-02-23 1986-04-11 Sanofi Sa ANTIFUNGAL PHARMACEUTICAL COMPOSITIONS FOR ORAL USE CONTAINING OMOCONAZOLE
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
DE3413365A1 (en) * 1984-04-09 1985-12-19 Merz + Co GmbH & Co, 6000 Frankfurt SUBSTITUTED PHENYLETHYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS
IT1200422B (en) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog COMPOUND WITH ANTIMICROBIA ACTIVITY, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT
ES2249992B1 (en) 2004-09-13 2007-03-01 Ferrer Internacional, S.A. A PROCEDURE FOR MANUFACTURING ENANTIOMERIC COMPOUNDS OF IMIDAZOL.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (en) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Method for preparing imidazole derivatives
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Also Published As

Publication number Publication date
AU4714979A (en) 1979-11-22
FR2426047B1 (en) 1982-11-05
DK153838C (en) 1989-01-30
FI71309B (en) 1986-09-09
NL930014I1 (en) 1993-05-03
YU112279A (en) 1983-01-21
JPS605592B2 (en) 1985-02-12
GB2025395B (en) 1982-07-28
DE2917244A1 (en) 1979-11-22
SE7904319L (en) 1979-11-19
PT69537A (en) 1979-05-01
NL189255C (en) 1993-02-16
GB2025395A (en) 1980-01-23
HU182565B (en) 1984-02-28
NO152840C (en) 1985-11-27
NO152840B (en) 1985-08-19
AU523053B2 (en) 1982-07-08
IL57245A0 (en) 1979-09-30
DK196579A (en) 1979-11-19
ES480552A1 (en) 1980-04-01
DK153838B (en) 1988-09-12
CH639075A5 (en) 1983-10-31
MX5927E (en) 1984-08-29
ATA345079A (en) 1983-04-15
FI791543A (en) 1979-11-19
AT372950B (en) 1983-11-25
NO791599L (en) 1979-11-20
AR219596A1 (en) 1980-08-29
GR68396B (en) 1981-12-29
FR2426047A1 (en) 1979-12-14
EG14345A (en) 1983-09-30
IE48372B1 (en) 1984-12-26
IL57245A (en) 1983-02-23
CA1115718A (en) 1982-01-05
DD143608A5 (en) 1980-09-03
NL930014I2 (en) 1993-09-16
NL7903872A (en) 1979-11-20
ZA792015B (en) 1980-04-30
IT7823546A0 (en) 1978-05-18
IT1096361B (en) 1985-08-26
SE444812B (en) 1986-05-12
DE2917244C2 (en) 1985-09-05
JPS54151974A (en) 1979-11-29
FI71309C (en) 1986-12-19
NZ190412A (en) 1981-03-16
PH14782A (en) 1981-12-09
SU816399A3 (en) 1981-03-23

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Legal Events

Date Code Title Description
SPCF Request for grant of supplementary protection certificate

Free format text: SPC 63/93:19930629

SPCG Supplementary protection certificate granted

Free format text: SPC 63/93 EXPIRES:20001013

MK9A Patent expired