SE7904319L - SUBSTITUTED DIBENSILETERS AND PROCEDURES FOR THE PREPARATION OF THEM - Google Patents

SUBSTITUTED DIBENSILETERS AND PROCEDURES FOR THE PREPARATION OF THEM

Info

Publication number
SE7904319L
SE7904319L SE7904319A SE7904319A SE7904319L SE 7904319 L SE7904319 L SE 7904319L SE 7904319 A SE7904319 A SE 7904319A SE 7904319 A SE7904319 A SE 7904319A SE 7904319 L SE7904319 L SE 7904319L
Authority
SE
Sweden
Prior art keywords
phenylthio
dibensileters
procedures
substituted
preparation
Prior art date
Application number
SE7904319A
Other languages
Swedish (sv)
Other versions
SE444812B (en
Inventor
D Nardi
E Massarani
A Tajana
M Veronese
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of SE7904319L publication Critical patent/SE7904319L/en
Publication of SE444812B publication Critical patent/SE444812B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Abstract

Novel compounds I and their acid addition salts <IMAGE> in which R is phenyl or phenylthio show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'- dichlorophenyl)-2-(N-imidazolyl- methyl)-ethanol with 4-chloromethyl- biphenyl, 4-bromomethyl-biphenyl, 1- phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide.
SE7904319A 1978-05-18 1979-05-17 IMIDAZOLE DERIVATIVES AND ACID ADDITION SALTS THEREOF, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE IMIDIZOL DERIVATIVES SE444812B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (en) 1978-05-18 1978-05-18 THERAPEUTICALLY ACTIVE REPLACED BONDS

Publications (2)

Publication Number Publication Date
SE7904319L true SE7904319L (en) 1979-11-19
SE444812B SE444812B (en) 1986-05-12

Family

ID=11208025

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7904319A SE444812B (en) 1978-05-18 1979-05-17 IMIDAZOLE DERIVATIVES AND ACID ADDITION SALTS THEREOF, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE IMIDIZOL DERIVATIVES

Country Status (29)

Country Link
JP (1) JPS605592B2 (en)
AR (1) AR219596A1 (en)
AT (1) AT372950B (en)
AU (1) AU523053B2 (en)
CA (1) CA1115718A (en)
CH (1) CH639075A5 (en)
DD (1) DD143608A5 (en)
DE (1) DE2917244C2 (en)
DK (1) DK153838C (en)
EG (1) EG14345A (en)
ES (1) ES480552A1 (en)
FI (1) FI71309C (en)
FR (1) FR2426047A1 (en)
GB (1) GB2025395B (en)
GR (1) GR68396B (en)
HU (1) HU182565B (en)
IE (1) IE48372B1 (en)
IL (1) IL57245A (en)
IT (1) IT1096361B (en)
MX (1) MX5927E (en)
NL (2) NL189255C (en)
NO (1) NO152840C (en)
NZ (1) NZ190412A (en)
PH (1) PH14782A (en)
PT (1) PT69537A (en)
SE (1) SE444812B (en)
SU (1) SU816399A3 (en)
YU (1) YU112279A (en)
ZA (1) ZA792015B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1155853A (en) * 1980-06-06 1983-10-25 Joseph A. Martin Imidazole derivatives and preparation thereof
FR2541114B1 (en) * 1983-02-23 1986-04-11 Sanofi Sa ANTIFUNGAL PHARMACEUTICAL COMPOSITIONS FOR ORAL USE CONTAINING OMOCONAZOLE
EP0117811A3 (en) * 1983-02-23 1987-06-03 Sanofi S.A. Fungicidal pharmaceutical compositions for oral administration
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
DE3413365A1 (en) * 1984-04-09 1985-12-19 Merz + Co GmbH & Co, 6000 Frankfurt SUBSTITUTED PHENYLETHYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS
IT1200422B (en) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog COMPOUND WITH ANTIMICROBIA ACTIVITY, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT
ES2249992B1 (en) * 2004-09-13 2007-03-01 Ferrer Internacional, S.A. A PROCEDURE FOR MANUFACTURING ENANTIOMERIC COMPOUNDS OF IMIDAZOL.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (en) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Method for preparing imidazole derivatives
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Also Published As

Publication number Publication date
DD143608A5 (en) 1980-09-03
FI71309C (en) 1986-12-19
NL7903872A (en) 1979-11-20
NL930014I2 (en) 1993-09-16
MX5927E (en) 1984-08-29
FR2426047A1 (en) 1979-12-14
ZA792015B (en) 1980-04-30
AT372950B (en) 1983-11-25
DE2917244C2 (en) 1985-09-05
AU4714979A (en) 1979-11-22
FI791543A (en) 1979-11-19
IE48372B1 (en) 1984-12-26
NL930014I1 (en) 1993-05-03
JPS605592B2 (en) 1985-02-12
FR2426047B1 (en) 1982-11-05
DE2917244A1 (en) 1979-11-22
DK196579A (en) 1979-11-19
DK153838B (en) 1988-09-12
FI71309B (en) 1986-09-09
PH14782A (en) 1981-12-09
IL57245A0 (en) 1979-09-30
ES480552A1 (en) 1980-04-01
NO152840B (en) 1985-08-19
IE790958L (en) 1979-11-18
IT1096361B (en) 1985-08-26
JPS54151974A (en) 1979-11-29
SE444812B (en) 1986-05-12
PT69537A (en) 1979-05-01
NO791599L (en) 1979-11-20
CH639075A5 (en) 1983-10-31
IT7823546A0 (en) 1978-05-18
SU816399A3 (en) 1981-03-23
YU112279A (en) 1983-01-21
HU182565B (en) 1984-02-28
ATA345079A (en) 1983-04-15
IL57245A (en) 1983-02-23
NL189255C (en) 1993-02-16
EG14345A (en) 1983-09-30
CA1115718A (en) 1982-01-05
AU523053B2 (en) 1982-07-08
GB2025395B (en) 1982-07-28
DK153838C (en) 1989-01-30
GR68396B (en) 1981-12-29
GB2025395A (en) 1980-01-23
NZ190412A (en) 1981-03-16
NO152840C (en) 1985-11-27
AR219596A1 (en) 1980-08-29

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