DE2830475A1 - Verfahren zum trennen von diastereoisomeren des 3-)3,4-dibenzyloxyphenyl)- serins - Google Patents

Verfahren zum trennen von diastereoisomeren des 3-)3,4-dibenzyloxyphenyl)- serins

Info

Publication number
DE2830475A1
DE2830475A1 DE19782830475 DE2830475A DE2830475A1 DE 2830475 A1 DE2830475 A1 DE 2830475A1 DE 19782830475 DE19782830475 DE 19782830475 DE 2830475 A DE2830475 A DE 2830475A DE 2830475 A1 DE2830475 A1 DE 2830475A1
Authority
DE
Germany
Prior art keywords
mixture
salts
isomers
threo
dibenzyloxyphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782830475
Other languages
German (de)
English (en)
Inventor
Junki Katsube
Hyogo Nishinomiya
Nachito Ohashi
Yoshinori Takashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of DE2830475A1 publication Critical patent/DE2830475A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782830475 1977-07-11 1978-07-11 Verfahren zum trennen von diastereoisomeren des 3-)3,4-dibenzyloxyphenyl)- serins Withdrawn DE2830475A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8312877A JPS5419931A (en) 1977-07-11 1977-07-11 Separation of threo, erythro-3-(3,4-dibenzyloxyphenyl)serines

Publications (1)

Publication Number Publication Date
DE2830475A1 true DE2830475A1 (de) 1979-01-25

Family

ID=13793551

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782830475 Withdrawn DE2830475A1 (de) 1977-07-11 1978-07-11 Verfahren zum trennen von diastereoisomeren des 3-)3,4-dibenzyloxyphenyl)- serins

Country Status (13)

Country Link
US (1) US4246428A (enExample)
JP (1) JPS5419931A (enExample)
AT (1) AT356646B (enExample)
AU (1) AU516261B2 (enExample)
BE (1) BE868797A (enExample)
CA (1) CA1100149A (enExample)
CH (1) CH634824A5 (enExample)
DE (1) DE2830475A1 (enExample)
ES (1) ES471639A1 (enExample)
FR (1) FR2397392A1 (enExample)
GB (1) GB2000779B (enExample)
IT (1) IT1159895B (enExample)
NL (1) NL7807469A (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4480109A (en) * 1982-01-14 1984-10-30 Sumitomo Chemical Company, Limited Process for producing threo-3-(3,4-dihydroxyphenyl)serine
JPS59112949A (ja) * 1982-12-20 1984-06-29 Microbial Chem Res Found 新規なｌ−スレオ−アドレナリン酸
CA1223602A (en) * 1983-05-25 1987-06-30 Naohito Ohashi Process for producing 3-(3,4-dihydroxyphenyl) serine
US8158149B2 (en) * 2004-05-12 2012-04-17 Chelsea Therapeutics, Inc. Threo-DOPS controlled release formulation
WO2004100929A1 (en) 2003-05-12 2004-11-25 Synergia Pharma, Inc. Threo-dops controlled release formulation
WO2005025561A1 (en) * 2003-09-04 2005-03-24 Synergia Pharma, Inc. Compositions and methods for orthostatic intolerance
DK1948155T3 (da) * 2006-06-28 2012-07-02 Chelsea Therapeutics Inc Farmaceutiske præparater omfattende droxidopa
ES2480966T3 (es) * 2007-03-09 2014-07-29 Chelsea Therapeutics, Inc. Droxidopa y composición farmacéutica de la misma para el tratamiento de la fibromialgia
AU2008248382B2 (en) * 2007-05-07 2013-07-18 Chelsea Therapeutics, Inc. Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders
JP5880913B2 (ja) 2011-05-17 2016-03-09 三郎 佐古田 パーキンソン病の体幹症状（姿勢反射異常）の治療剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182079A (en) * 1962-11-19 1965-05-04 Ajinomoto Kk Optical resolution of dl-valine
CH505785A (de) * 1969-02-07 1971-04-15 Hoffmann La Roche Verfahren zur Herstellung von (-)threo-3-(4-Hydroxy-3-methoxy-phenyl)-serin
US3830836A (en) * 1970-10-15 1974-08-20 Ajimoto Kk 3,4-dihydroxyphenylalanine hemihydrochloride

Also Published As

Publication number Publication date
AU3787078A (en) 1980-01-10
ATA499578A (de) 1979-10-15
AU516261B2 (en) 1981-05-28
CA1100149A (en) 1981-04-28
ES471639A1 (es) 1979-02-01
GB2000779B (en) 1982-01-20
IT1159895B (it) 1987-03-04
US4246428A (en) 1981-01-20
NL7807469A (nl) 1979-01-15
IT7868640A0 (it) 1978-07-11
FR2397392B1 (enExample) 1982-04-30
FR2397392A1 (fr) 1979-02-09
JPS6131097B2 (enExample) 1986-07-17
JPS5419931A (en) 1979-02-15
BE868797A (fr) 1979-01-08
GB2000779A (en) 1979-01-17
CH634824A5 (de) 1983-02-28
AT356646B (de) 1980-05-12

Similar Documents

Publication Publication Date Title
EP0822935B1 (de) Verfahren zur herstellung von enantiomerenreinen tropasäureestern
DE1543374C3 (de) 3,4 Dihydroxyphenylalkanolamine und ihre Saureadditionssalze, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen
DE2830475A1 (de) Verfahren zum trennen von diastereoisomeren des 3-)3,4-dibenzyloxyphenyl)- serins
DE60123125T2 (de) Verfahren zur herstellung von 1-(aminomethyl) cyclohexanessigsäure
DE2003486C3 (de) Verfahren zur Spaltung von racemisehen organischen Aminen durch die ( )-Di-O-isopropyliden-2-keto-L-gulonsäure
DE69020989T2 (de) Verfahren zur Racematspaltung von 5-alkoxy-substituierten (+/-)-1,3-dimethyloxindolylethylaminen.
DE602004009831T2 (de) Verfahren zur gewinnung von tolterodin
DD209805A5 (de) Verfahren zur herstellung von (d)-2-(6-methoxy-2-naphthyl)-propionsaeure
CH629192A5 (en) Process for the preparation of optically active C(1)-C(3)-alkyl esters of 1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid
JPS5982365A (ja) 新規なラセミ分割ケト化合物およびその製法
EP0728736B1 (de) Verfahren zur Herstellung von optisch aktivem tert-Leucinol und dessen Verwendung
DE69015907T2 (de) Verfahren zur optischen Trennung von Dropropizin.
DE745314C (de) Verfahren zur Herstellung von analgetisch wirkenden 1-Oxyphenyl-3-aminoalkylverbindungen
DE2400658A1 (de) Aminopropanolderivate des p-acetamidophenols und verfahren zu ihrer herstellung
DE2558508A1 (de) Verfahren zur racematspaltung von dl-pantolacton
DE2354327A1 (de) Verfahren zur herstellung von 6,7benzomorphanen
DE1124496B (de) Verfahren zur Herstellung von tertiaeren Aminen, ihren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen
DE2943125A1 (de) Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
DE943947C (de) Verfahren zur Herstellung der erythro-1-p-Nitrophenyl-2-amino-1, 3-propandiole
DE966534C (de) Verfahren zur Herstellung von basisch substituierten Pyridinverbindungen
DE2749203A1 (de) Verfahren zur racematspaltung von dl-alpha-aminocarbonsaeuren
DE1249881B (de) Verfahren zur Herstellung von Phenylathanolammen und deren Salzen
DE19647538A1 (de) Verfahren zur Herstellung von enantiomerenreinem N-Methyl-N-[1-phenyl-2-(-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-diphenylacetamid
CH581625A5 (en) 2-dimethylallylbenzomorphans - analgesics
DE2838882A1 (de) Optisch aktive salze der mandelsaeure und verfahren zur optischen spaltung von dl-mandelsaeure mit diesen salzen als zwischenprodukten

Legal Events

Date Code Title Description
OI Miscellaneous see part 1
8141 Disposal/no request for examination