DE2815853A1 - Gereinigte urokinasepraeparate und verfahren zu ihrer herstellung - Google Patents

Gereinigte urokinasepraeparate und verfahren zu ihrer herstellung

Info

Publication number
DE2815853A1
DE2815853A1 DE19782815853 DE2815853A DE2815853A1 DE 2815853 A1 DE2815853 A1 DE 2815853A1 DE 19782815853 DE19782815853 DE 19782815853 DE 2815853 A DE2815853 A DE 2815853A DE 2815853 A1 DE2815853 A1 DE 2815853A1
Authority
DE
Germany
Prior art keywords
urokinase
resin
mol
activity
plasminogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782815853
Other languages
German (de)
English (en)
Inventor
Jean Choay
Jean Goulay
Jean-Claude Lormeau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Choay SA
Original Assignee
Choay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay SA filed Critical Choay SA
Publication of DE2815853A1 publication Critical patent/DE2815853A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19782815853 1977-04-12 1978-04-12 Gereinigte urokinasepraeparate und verfahren zu ihrer herstellung Withdrawn DE2815853A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7711004A FR2387242A1 (fr) 1977-04-12 1977-04-12 Compositions purifiees d'urokinase et procede pour leur obtention

Publications (1)

Publication Number Publication Date
DE2815853A1 true DE2815853A1 (de) 1978-10-19

Family

ID=9189313

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782815853 Withdrawn DE2815853A1 (de) 1977-04-12 1978-04-12 Gereinigte urokinasepraeparate und verfahren zu ihrer herstellung

Country Status (10)

Country Link
JP (1) JPS53130485A (xx)
BE (1) BE865926A (xx)
DE (1) DE2815853A1 (xx)
DK (1) DK159878A (xx)
ES (1) ES468720A1 (xx)
FR (1) FR2387242A1 (xx)
IT (1) IT1156188B (xx)
LU (1) LU79426A1 (xx)
NL (1) NL7803888A (xx)
SE (1) SE7804141L (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015583A (en) * 1985-04-11 1991-05-14 Behringwerke Aktiengesellschaft Process for the purification of plasminogen activators (PA)
EP1245681A2 (en) * 2001-03-16 2002-10-02 Cerbios-Pharma S.A. A method for the production of pharmaceutically active recombinant proteins comprising the use of alkanoic acids, their derivatives or salts thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5411219A (en) * 1977-06-25 1979-01-27 Green Cross Corp:The Thrombolytic agent and its preparation
AU6642281A (en) * 1979-11-13 1981-06-03 Husain, S.S. Isolation of plasminogen activators useful as therapeutic anddiagnostic agents
JPS606191A (ja) * 1983-06-02 1985-01-12 Wakamoto Pharmaceut Co Ltd 低分子ウロキナ−ゼと高分子ウロキナ−ゼの分離方法
DE3439980A1 (de) * 1984-11-02 1986-05-07 Behringwerke Ag, 3550 Marburg Verfahren zur reinigung sowie pasteurisierung von urokinase

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015583A (en) * 1985-04-11 1991-05-14 Behringwerke Aktiengesellschaft Process for the purification of plasminogen activators (PA)
EP1245681A2 (en) * 2001-03-16 2002-10-02 Cerbios-Pharma S.A. A method for the production of pharmaceutically active recombinant proteins comprising the use of alkanoic acids, their derivatives or salts thereof
EP1245681A3 (en) * 2001-03-16 2003-12-03 Cerbios-Pharma S.A. A method for the production of pharmaceutically active recombinant proteins comprising the use of alkanoic acids, their derivatives or salts thereof

Also Published As

Publication number Publication date
IT7848859A0 (it) 1978-04-12
ES468720A1 (es) 1978-12-16
JPS53130485A (en) 1978-11-14
FR2387242A1 (fr) 1978-11-10
NL7803888A (nl) 1978-10-16
DK159878A (da) 1978-10-13
LU79426A1 (fr) 1978-11-28
IT1156188B (it) 1987-01-28
BE865926A (fr) 1978-10-12
SE7804141L (sv) 1978-10-13

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee