DE69303941T2 - Verfahren zur Herstellung von hochreinem Fibrinogen - Google Patents

Verfahren zur Herstellung von hochreinem Fibrinogen

Info

Publication number
DE69303941T2
DE69303941T2 DE69303941T DE69303941T DE69303941T2 DE 69303941 T2 DE69303941 T2 DE 69303941T2 DE 69303941 T DE69303941 T DE 69303941T DE 69303941 T DE69303941 T DE 69303941T DE 69303941 T2 DE69303941 T2 DE 69303941T2
Authority
DE
Germany
Prior art keywords
fibrinogen
solution
ionic strength
agarose
nacl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69303941T
Other languages
English (en)
Other versions
DE69303941D1 (de
Inventor
Bernard Dazey
Mohamed Hamsany
Sylvia Enfedaque-Morer
Gerard Vezon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AQUITAINE DEV TRANSF SANGUINE
Original Assignee
AQUITAINE DEV TRANSF SANGUINE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AQUITAINE DEV TRANSF SANGUINE filed Critical AQUITAINE DEV TRANSF SANGUINE
Publication of DE69303941D1 publication Critical patent/DE69303941D1/de
Application granted granted Critical
Publication of DE69303941T2 publication Critical patent/DE69303941T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Materials For Medical Uses (AREA)
DE69303941T 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen Expired - Fee Related DE69303941T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201238A FR2686883B1 (fr) 1992-02-04 1992-02-04 Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.

Publications (2)

Publication Number Publication Date
DE69303941D1 DE69303941D1 (de) 1996-09-19
DE69303941T2 true DE69303941T2 (de) 1997-03-27

Family

ID=9426316

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69303941T Expired - Fee Related DE69303941T2 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen
DE93400247T Pending DE555135T1 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE93400247T Pending DE555135T1 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung.

Country Status (7)

Country Link
EP (1) EP0555135B1 (de)
AT (1) ATE141284T1 (de)
DE (2) DE69303941T2 (de)
DK (1) DK0555135T3 (de)
ES (1) ES2049701T3 (de)
FR (1) FR2686883B1 (de)
GR (2) GR930300095T1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261126A1 (de) * 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
US8741846B2 (en) 2008-06-23 2014-06-03 Bio-Products & Bio-Engineering Ag Storage-stable, functionally intact fibrinogen

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0602173B1 (de) * 1991-09-05 1999-05-26 Baxter International Inc. Topischer fibrinogenkomplex
WO1996002571A1 (fr) * 1994-07-14 1996-02-01 Croix-Rouge De Belgique Concentre de fibrinogene issu de plasma sanguin, procede et installation pour sa preparation
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
WO2012038410A1 (en) * 2010-09-20 2012-03-29 Octapharma Ag Process for production of fibrinogen
US10112972B2 (en) 2012-03-13 2018-10-30 Octapharma Ag Process for production of fibrinogen and fibrinogen produced thereby
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
FR2644064B1 (fr) * 1989-02-17 1994-05-27 Aquitaine Dev Transf Sanguine Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
IT1248723B (it) * 1990-06-12 1995-01-26 Scalvo S P A Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261126A1 (de) * 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
US8741846B2 (en) 2008-06-23 2014-06-03 Bio-Products & Bio-Engineering Ag Storage-stable, functionally intact fibrinogen

Also Published As

Publication number Publication date
FR2686883A1 (fr) 1993-08-06
DE69303941D1 (de) 1996-09-19
EP0555135B1 (de) 1996-08-14
EP0555135A1 (de) 1993-08-11
DK0555135T3 (da) 1996-11-25
FR2686883B1 (fr) 1994-05-13
ES2049701T3 (es) 1997-01-16
ATE141284T1 (de) 1996-08-15
GR3021419T3 (en) 1997-01-31
ES2049701T1 (es) 1994-05-01
DE555135T1 (de) 1994-03-31
GR930300095T1 (en) 1993-09-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GROSSE, BOCKHORNI, SCHUMACHER, 81476 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: BOCKHORNI & KOLLEGEN, 80687 MUENCHEN

8339 Ceased/non-payment of the annual fee