DE555135T1 - Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung. - Google Patents

Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung.

Info

Publication number
DE555135T1
DE555135T1 DE93400247T DE93400247T DE555135T1 DE 555135 T1 DE555135 T1 DE 555135T1 DE 93400247 T DE93400247 T DE 93400247T DE 93400247 T DE93400247 T DE 93400247T DE 555135 T1 DE555135 T1 DE 555135T1
Authority
DE
Germany
Prior art keywords
fibrinogen
high purity
solution
ionic strength
agarose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE93400247T
Other languages
English (en)
Inventor
Bernard Dazey
Mohamed Hamsany
Sylvia Enfedaque-Morer
Gerard Vezon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AQUITAINE DEV TRANSF SANGUINE
Original Assignee
AQUITAINE DEV TRANSF SANGUINE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AQUITAINE DEV TRANSF SANGUINE filed Critical AQUITAINE DEV TRANSF SANGUINE
Publication of DE555135T1 publication Critical patent/DE555135T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Materials For Medical Uses (AREA)
DE93400247T 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung. Pending DE555135T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201238A FR2686883B1 (fr) 1992-02-04 1992-02-04 Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.

Publications (1)

Publication Number Publication Date
DE555135T1 true DE555135T1 (de) 1994-03-31

Family

ID=9426316

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69303941T Expired - Fee Related DE69303941T2 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen
DE93400247T Pending DE555135T1 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen, hochreines Fibrinogen so erhalten und dieses enthaltende pharmazeutische Zusammensetzung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69303941T Expired - Fee Related DE69303941T2 (de) 1992-02-04 1993-02-02 Verfahren zur Herstellung von hochreinem Fibrinogen

Country Status (7)

Country Link
EP (1) EP0555135B1 (de)
AT (1) ATE141284T1 (de)
DE (2) DE69303941T2 (de)
DK (1) DK0555135T3 (de)
ES (1) ES2049701T3 (de)
FR (1) FR2686883B1 (de)
GR (2) GR930300095T1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE180492T1 (de) * 1991-09-05 1999-06-15 Baxter Int Topischer fibrinogenkomplex
ES2139227T5 (es) * 1994-07-14 2011-05-04 Caf-Dcf Département Central De Fractionnement De La Croix Rouge S.C.R.L. Concentrado de fibrinógeno obtenido de plasma sanguíneo, procedimiento e instalación para su preparación.
DE10261126A1 (de) * 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
WO2009155626A2 (de) 2008-06-23 2009-12-30 Bio-Products & Bio-Engineering Ag Lagerstabiles, funktionell intaktes fibrinogen
CN106046147B (zh) * 2010-09-20 2019-11-19 欧克塔医药公司 纤维蛋白原生产方法
ES2642383T3 (es) 2012-03-13 2017-11-16 Octapharma Ag Procedimiento mejorado de producción de fibrinógeno y fibrinógeno producido por el mismo
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
FR2644064B1 (fr) * 1989-02-17 1994-05-27 Aquitaine Dev Transf Sanguine Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
IT1248723B (it) * 1990-06-12 1995-01-26 Scalvo S P A Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo

Also Published As

Publication number Publication date
EP0555135B1 (de) 1996-08-14
ES2049701T1 (es) 1994-05-01
DE69303941D1 (de) 1996-09-19
DE69303941T2 (de) 1997-03-27
EP0555135A1 (de) 1993-08-11
FR2686883B1 (fr) 1994-05-13
GR3021419T3 (en) 1997-01-31
ES2049701T3 (es) 1997-01-16
GR930300095T1 (en) 1993-09-30
DK0555135T3 (da) 1996-11-25
ATE141284T1 (de) 1996-08-15
FR2686883A1 (fr) 1993-08-06

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