DE2809794C2 - - Google Patents

Info

Publication number
DE2809794C2
DE2809794C2 DE2809794A DE2809794A DE2809794C2 DE 2809794 C2 DE2809794 C2 DE 2809794C2 DE 2809794 A DE2809794 A DE 2809794A DE 2809794 A DE2809794 A DE 2809794A DE 2809794 C2 DE2809794 C2 DE 2809794C2
Authority
DE
Germany
Prior art keywords
salt
ethylamine
acid
diluent
enantiomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2809794A
Other languages
German (de)
English (en)
Other versions
DE2809794A1 (de
Inventor
John Stuart Beeston Nottinghamshire Gb Nicholson
James Gordon Nuthall Nottinghamshire Gb Tantum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9697/77A external-priority patent/GB1596032A/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of DE2809794A1 publication Critical patent/DE2809794A1/de
Application granted granted Critical
Publication of DE2809794C2 publication Critical patent/DE2809794C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782809794 1977-03-08 1978-03-07 Verfahren zur erhoehung des anteils an einem gewuenschten enantiomeren einer 2-arylpropionsaeure Granted DE2809794A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9697/77A GB1596032A (en) 1977-03-08 1977-03-08 Resolution of optically active 2-arylpropionic acids
GB194678 1978-01-18

Publications (2)

Publication Number Publication Date
DE2809794A1 DE2809794A1 (de) 1978-09-21
DE2809794C2 true DE2809794C2 (ja) 1989-08-03

Family

ID=26237091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782809794 Granted DE2809794A1 (de) 1977-03-08 1978-03-07 Verfahren zur erhoehung des anteils an einem gewuenschten enantiomeren einer 2-arylpropionsaeure

Country Status (29)

Country Link
JP (1) JPS53112841A (ja)
AT (1) AT360508B (ja)
AU (1) AU521708B2 (ja)
BG (1) BG28567A3 (ja)
CA (1) CA1105942A (ja)
CH (1) CH638482A5 (ja)
CS (1) CS222255B2 (ja)
DD (1) DD136261A5 (ja)
DE (1) DE2809794A1 (ja)
DK (1) DK154418C (ja)
EG (1) EG13345A (ja)
ES (1) ES467606A1 (ja)
FI (1) FI66828C (ja)
FR (1) FR2383155A1 (ja)
GR (1) GR64816B (ja)
HU (1) HU178810B (ja)
IE (1) IE46476B1 (ja)
IN (1) IN147834B (ja)
IT (1) IT1202818B (ja)
LU (1) LU79186A1 (ja)
NL (1) NL189126C (ja)
NO (1) NO146197C (ja)
NZ (1) NZ186644A (ja)
PH (1) PH13333A (ja)
PL (1) PL110888B1 (ja)
PT (1) PT67743A (ja)
SE (1) SE436422B (ja)
SU (1) SU784759A3 (ja)
YU (1) YU41472B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2826952A1 (de) * 1978-06-20 1980-01-10 Bayer Ag Enantiomerentrennung von chiralen carbonsaeuren
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
JPS57145830A (en) * 1981-03-06 1982-09-09 Hiroyuki Nohira Optical resolution of 2-(4-chlorophenyl)-3-methylbutanoic acid
JPH01126425U (ja) * 1988-02-23 1989-08-29
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
JP3782834B2 (ja) 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
DE19717429A1 (de) * 1997-04-25 1998-12-24 Bayer Ag Herstellung enantiomerenreiner Biarylketocarbonsäuren
CN102388014A (zh) 2009-02-06 2012-03-21 帝斯曼知识产权资产管理有限公司 手性α-芳基丙酸衍生物的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23268A (en) * 1964-05-07 1969-02-27 Merck & Co Inc Anti-inflammatory preparations containing the 4-phenyl-alpha-methyl acid acetic phenyl acid
FR2015728A1 (en) * 1968-04-18 1970-04-30 Lilly Co Eli Anti-inflammatory substd-phenylalkanoic acids and - derivs
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids

Also Published As

Publication number Publication date
SE7802603L (sv) 1978-09-09
LU79186A1 (fr) 1978-09-18
PT67743A (en) 1978-04-01
FR2383155A1 (fr) 1978-10-06
BG28567A3 (ja) 1980-05-15
FR2383155B1 (ja) 1983-12-30
IT7848320A0 (it) 1978-03-07
HU178810B (en) 1982-06-28
CS222255B2 (en) 1983-06-24
NO146197B (no) 1982-05-10
NL189126B (nl) 1992-08-17
DD136261A5 (de) 1979-06-27
DK154418C (da) 1989-06-19
IN147834B (ja) 1980-07-19
NO780785L (no) 1978-09-11
IT1202818B (it) 1989-02-09
YU54078A (en) 1984-04-30
PL205161A1 (pl) 1979-03-26
NL189126C (nl) 1993-01-18
FI780738A (fi) 1978-09-09
JPS53112841A (en) 1978-10-02
CH638482A5 (en) 1983-09-30
ES467606A1 (es) 1978-10-16
AU521708B2 (en) 1982-04-29
DK100878A (da) 1978-09-09
ATA163478A (de) 1980-06-15
YU41472B (en) 1987-08-31
NL7802520A (nl) 1978-09-12
DE2809794A1 (de) 1978-09-21
NZ186644A (en) 1980-10-24
AT360508B (de) 1981-01-12
NO146197C (no) 1982-08-18
SU784759A3 (ru) 1980-11-30
AU3397778A (en) 1979-09-13
IE780467L (en) 1978-09-08
SE436422B (sv) 1984-12-10
PH13333A (en) 1980-03-13
IE46476B1 (en) 1983-06-29
CA1105942A (en) 1981-07-28
FI66828C (fi) 1984-12-10
JPS626536B2 (ja) 1987-02-12
EG13345A (en) 1981-06-30
FI66828B (fi) 1984-08-31
GR64816B (en) 1980-06-03
PL110888B1 (en) 1980-08-30
DK154418B (da) 1988-11-14

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Legal Events

Date Code Title Description
8126 Change of the secondary classification

Free format text: C07C 59/68 A61K 31/19 C07C 57/58

8127 New person/name/address of the applicant

Owner name: THE BOOTS CO. PLC, NOTTINGHAM, GB

8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: SCHWABE, H., DIPL.-ING. SANDMAIR, K., DIPL.-CHEM.

D2 Grant after examination
8364 No opposition during term of opposition