DE2710062A1 - Neue cholesterinderivate - Google Patents

Neue cholesterinderivate

Info

Publication number
DE2710062A1
DE2710062A1 DE19772710062 DE2710062A DE2710062A1 DE 2710062 A1 DE2710062 A1 DE 2710062A1 DE 19772710062 DE19772710062 DE 19772710062 DE 2710062 A DE2710062 A DE 2710062A DE 2710062 A1 DE2710062 A1 DE 2710062A1
Authority
DE
Germany
Prior art keywords
mixture
formula
solution
acetonide
cholestadiene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772710062
Other languages
German (de)
English (en)
Inventor
Enrico Baggiolini
Jun John Joseph Partridge
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,848 external-priority patent/US4026882A/en
Priority claimed from US05/664,799 external-priority patent/US4021423A/en
Priority claimed from US05/664,833 external-priority patent/US4028349A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2710062A1 publication Critical patent/DE2710062A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19772710062 1976-03-08 1977-03-08 Neue cholesterinderivate Ceased DE2710062A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/664,848 US4026882A (en) 1976-03-08 1976-03-08 Syntheses of 3,24R,25- and 3,24S,25-trihydroxy-5,7-cholestadiene 24,25-ketals and alkanoyl derivatives thereof
US05/664,799 US4021423A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol
US05/664,833 US4028349A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof

Publications (1)

Publication Number Publication Date
DE2710062A1 true DE2710062A1 (de) 1977-09-15

Family

ID=27418118

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772710062 Ceased DE2710062A1 (de) 1976-03-08 1977-03-08 Neue cholesterinderivate

Country Status (7)

Country Link
JP (1) JPS52108960A (enExample)
CH (4) CH626336A5 (enExample)
DE (1) DE2710062A1 (enExample)
FR (1) FR2343727A1 (enExample)
GB (1) GB1572952A (enExample)
IT (1) IT1078064B (enExample)
NL (1) NL7702484A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735599A (en) * 1980-08-05 1982-02-26 Chugai Pharmaceut Co Ltd 24,25-dihydroxycholestane and its preparation
ATE15050T1 (de) * 1981-04-29 1985-09-15 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten und zwischenprodukte dafuer.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178427B (de) * 1961-01-26 1964-09-24 Olin Mathieson Verfahren zur Herstellung von 16ª‡, 17ª‡-Dihydroxysteroiden der Pregnanreihe
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
JPS51128417A (en) * 1975-04-28 1976-11-09 Teijin Ltd A method for stabilizing active vitamin d3 derivatives

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Fried, J.: Organic Reactions in Steroid Chemistry, Vol. 1, 1972, S. 387-388 u. 404-405 *
J. of Steroid Biochemistry, 1975, Vol. 6, S. 117-119 *
Tetrahedron Letters, Nr. 1, 1975, S. 15-18 *

Also Published As

Publication number Publication date
CH627764A5 (en) 1982-01-29
FR2343727A1 (fr) 1977-10-07
GB1572952A (en) 1980-08-06
IT1078064B (it) 1985-05-08
FR2343727B1 (enExample) 1984-01-13
NL7702484A (nl) 1977-09-12
JPS52108960A (en) 1977-09-12
CH627159A5 (en) 1981-12-31
CH626336A5 (en) 1981-11-13
CH627192A5 (en) 1981-12-31

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Legal Events

Date Code Title Description
OC Search report available
8110 Request for examination paragraph 44
8131 Rejection