GB1572952A - Cholecalciferol derivatives - Google Patents

Cholecalciferol derivatives Download PDF

Info

Publication number
GB1572952A
GB1572952A GB9480/77A GB948077A GB1572952A GB 1572952 A GB1572952 A GB 1572952A GB 9480/77 A GB9480/77 A GB 9480/77A GB 948077 A GB948077 A GB 948077A GB 1572952 A GB1572952 A GB 1572952A
Authority
GB
United Kingdom
Prior art keywords
dihydroxycholecalciferol
acetate
acetonide
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9480/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,848 external-priority patent/US4026882A/en
Priority claimed from US05/664,799 external-priority patent/US4021423A/en
Priority claimed from US05/664,833 external-priority patent/US4028349A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1572952A publication Critical patent/GB1572952A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB9480/77A 1976-03-08 1977-03-07 Cholecalciferol derivatives Expired GB1572952A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/664,848 US4026882A (en) 1976-03-08 1976-03-08 Syntheses of 3,24R,25- and 3,24S,25-trihydroxy-5,7-cholestadiene 24,25-ketals and alkanoyl derivatives thereof
US05/664,799 US4021423A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol
US05/664,833 US4028349A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof

Publications (1)

Publication Number Publication Date
GB1572952A true GB1572952A (en) 1980-08-06

Family

ID=27418118

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9480/77A Expired GB1572952A (en) 1976-03-08 1977-03-07 Cholecalciferol derivatives

Country Status (7)

Country Link
JP (1) JPS52108960A (enExample)
CH (4) CH626336A5 (enExample)
DE (1) DE2710062A1 (enExample)
FR (1) FR2343727A1 (enExample)
GB (1) GB1572952A (enExample)
IT (1) IT1078064B (enExample)
NL (1) NL7702484A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735599A (en) * 1980-08-05 1982-02-26 Chugai Pharmaceut Co Ltd 24,25-dihydroxycholestane and its preparation
ATE15050T1 (de) * 1981-04-29 1985-09-15 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten und zwischenprodukte dafuer.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178427B (de) * 1961-01-26 1964-09-24 Olin Mathieson Verfahren zur Herstellung von 16ª‡, 17ª‡-Dihydroxysteroiden der Pregnanreihe
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
JPS51128417A (en) * 1975-04-28 1976-11-09 Teijin Ltd A method for stabilizing active vitamin d3 derivatives

Also Published As

Publication number Publication date
DE2710062A1 (de) 1977-09-15
CH627764A5 (en) 1982-01-29
FR2343727A1 (fr) 1977-10-07
IT1078064B (it) 1985-05-08
FR2343727B1 (enExample) 1984-01-13
NL7702484A (nl) 1977-09-12
JPS52108960A (en) 1977-09-12
CH627159A5 (en) 1981-12-31
CH626336A5 (en) 1981-11-13
CH627192A5 (en) 1981-12-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee