DE2652961A1 - Propionsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel - Google Patents

Propionsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Info

Publication number
DE2652961A1
DE2652961A1 DE19762652961 DE2652961A DE2652961A1 DE 2652961 A1 DE2652961 A1 DE 2652961A1 DE 19762652961 DE19762652961 DE 19762652961 DE 2652961 A DE2652961 A DE 2652961A DE 2652961 A1 DE2652961 A1 DE 2652961A1
Authority
DE
Germany
Prior art keywords
ibuprofen
aluminum
water
propionic acid
flurbiprofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19762652961
Other languages
German (de)
English (en)
Inventor
Anthony Arthur Sinkula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DE2652961A1 publication Critical patent/DE2652961A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19762652961 1975-12-15 1976-11-22 Propionsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel Withdrawn DE2652961A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64043175A 1975-12-15 1975-12-15

Publications (1)

Publication Number Publication Date
DE2652961A1 true DE2652961A1 (de) 1977-06-16

Family

ID=24568211

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762652961 Withdrawn DE2652961A1 (de) 1975-12-15 1976-11-22 Propionsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Country Status (10)

Country Link
JP (1) JPS5273835A (xx)
AU (1) AU503656B2 (xx)
BE (1) BE849450A (xx)
CA (1) CA1062721A (xx)
DE (1) DE2652961A1 (xx)
FR (1) FR2335210A1 (xx)
GB (1) GB1527563A (xx)
MX (1) MX4487E (xx)
NL (1) NL7613426A (xx)
ZA (1) ZA766709B (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400363A1 (fr) * 1977-08-18 1979-03-16 Upjohn Co Compositions pharmaceutiques contenant un sel d'aluminium d'acide 2-(4-isobutylphenyl) propionique
DE3938227C1 (en) * 1989-11-17 1991-05-02 Dolorgiet Gmbh & Co Kg, 5205 St Augustin, De Oral antiinflammatory and analgetic pharmaceutical compsn. - comprises magnesium ibuprofen dissolved in mixt. of water, propane-1,2-diol and glycerol

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
DE3270988D1 (en) * 1981-07-20 1986-06-12 Upjohn Co Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
IT1175941B (it) * 1984-02-16 1987-08-12 Stabil Bioterapico Farmachim Sali d'alluminio mono, bi e trisostituiti degli acidi aril-alcanoici e composizioni farmaceutiche che li contengono
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US5028625A (en) * 1989-06-20 1991-07-02 American Home Products Corporation Acid addition salt of ibuprofen and meglumine
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
WO1998052545A1 (en) * 1997-05-22 1998-11-26 The Boots Company Plc Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat
CN111892618A (zh) * 2020-08-24 2020-11-06 运城鸿博化工有限公司 新结构受阻酚抗氧剂及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE811810A (en) * 1974-03-04 1974-09-04 2-(3-phenoxy-phenyl)-propionyloxy-aluminium - mono-or di-basic salts which form aq. suspensions without objectionable taste

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE811810A (en) * 1974-03-04 1974-09-04 2-(3-phenoxy-phenyl)-propionyloxy-aluminium - mono-or di-basic salts which form aq. suspensions without objectionable taste

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400363A1 (fr) * 1977-08-18 1979-03-16 Upjohn Co Compositions pharmaceutiques contenant un sel d'aluminium d'acide 2-(4-isobutylphenyl) propionique
DE3938227C1 (en) * 1989-11-17 1991-05-02 Dolorgiet Gmbh & Co Kg, 5205 St Augustin, De Oral antiinflammatory and analgetic pharmaceutical compsn. - comprises magnesium ibuprofen dissolved in mixt. of water, propane-1,2-diol and glycerol

Also Published As

Publication number Publication date
AU503656B2 (en) 1979-09-13
AU1951976A (en) 1978-05-18
MX4487E (es) 1982-05-21
ZA766709B (en) 1977-10-26
FR2335210B1 (xx) 1980-02-29
JPS5273835A (en) 1977-06-21
FR2335210A1 (fr) 1977-07-15
NL7613426A (nl) 1977-06-17
GB1527563A (en) 1978-10-04
BE849450A (fr) 1977-06-15
CA1062721A (en) 1979-09-18

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZ

8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee