CA1062721A - Propionic acid derivatives - Google Patents

Propionic acid derivatives

Info

Publication number
CA1062721A
CA1062721A CA265,001A CA265001A CA1062721A CA 1062721 A CA1062721 A CA 1062721A CA 265001 A CA265001 A CA 265001A CA 1062721 A CA1062721 A CA 1062721A
Authority
CA
Canada
Prior art keywords
aluminum
ibuprofen
flurbiprofen
acid
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA265,001A
Other languages
English (en)
French (fr)
Inventor
Anthony A. Sinkula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of CA1062721A publication Critical patent/CA1062721A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA265,001A 1975-12-15 1976-11-05 Propionic acid derivatives Expired CA1062721A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64043175A 1975-12-15 1975-12-15

Publications (1)

Publication Number Publication Date
CA1062721A true CA1062721A (en) 1979-09-18

Family

ID=24568211

Family Applications (1)

Application Number Title Priority Date Filing Date
CA265,001A Expired CA1062721A (en) 1975-12-15 1976-11-05 Propionic acid derivatives

Country Status (10)

Country Link
JP (1) JPS5273835A (xx)
AU (1) AU503656B2 (xx)
BE (1) BE849450A (xx)
CA (1) CA1062721A (xx)
DE (1) DE2652961A1 (xx)
FR (1) FR2335210A1 (xx)
GB (1) GB1527563A (xx)
MX (1) MX4487E (xx)
NL (1) NL7613426A (xx)
ZA (1) ZA766709B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
DE3270988D1 (en) * 1981-07-20 1986-06-12 Upjohn Co Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
IT1175941B (it) * 1984-02-16 1987-08-12 Stabil Bioterapico Farmachim Sali d'alluminio mono, bi e trisostituiti degli acidi aril-alcanoici e composizioni farmaceutiche che li contengono
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US5028625A (en) * 1989-06-20 1991-07-02 American Home Products Corporation Acid addition salt of ibuprofen and meglumine
DE3938227C1 (en) * 1989-11-17 1991-05-02 Dolorgiet Gmbh & Co Kg, 5205 St Augustin, De Oral antiinflammatory and analgetic pharmaceutical compsn. - comprises magnesium ibuprofen dissolved in mixt. of water, propane-1,2-diol and glycerol
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
WO1998052545A1 (en) * 1997-05-22 1998-11-26 The Boots Company Plc Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat
CN111892618A (zh) * 2020-08-24 2020-11-06 运城鸿博化工有限公司 新结构受阻酚抗氧剂及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE811810A (en) * 1974-03-04 1974-09-04 2-(3-phenoxy-phenyl)-propionyloxy-aluminium - mono-or di-basic salts which form aq. suspensions without objectionable taste

Also Published As

Publication number Publication date
AU503656B2 (en) 1979-09-13
AU1951976A (en) 1978-05-18
MX4487E (es) 1982-05-21
ZA766709B (en) 1977-10-26
FR2335210B1 (xx) 1980-02-29
JPS5273835A (en) 1977-06-21
FR2335210A1 (fr) 1977-07-15
NL7613426A (nl) 1977-06-17
GB1527563A (en) 1978-10-04
DE2652961A1 (de) 1977-06-16
BE849450A (fr) 1977-06-15

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