DE2627146C3 - Adriamycinester, Verfahren zu deren Herstellung und pharmazeutische Mittel enthaltend diese Adriamycinester - Google Patents

Adriamycinester, Verfahren zu deren Herstellung und pharmazeutische Mittel enthaltend diese Adriamycinester

Info

Publication number
DE2627146C3
DE2627146C3 DE762627146A DE2627146A DE2627146C3 DE 2627146 C3 DE2627146 C3 DE 2627146C3 DE 762627146 A DE762627146 A DE 762627146A DE 2627146 A DE2627146 A DE 2627146A DE 2627146 C3 DE2627146 C3 DE 2627146C3
Authority
DE
Germany
Prior art keywords
adriamycin
esters
glycolate
preparation
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE762627146A
Other languages
German (de)
English (en)
Other versions
DE2627146B2 (de
DE2627146A1 (de
Inventor
Federico Nerviano Mailand Arcamone
Luigi Bernardi
Aurelio Di Dr. Mailand Marco
Bianca Patelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of DE2627146A1 publication Critical patent/DE2627146A1/de
Publication of DE2627146B2 publication Critical patent/DE2627146B2/de
Application granted granted Critical
Publication of DE2627146C3 publication Critical patent/DE2627146C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE762627146A 1975-06-20 1976-06-16 Adriamycinester, Verfahren zu deren Herstellung und pharmazeutische Mittel enthaltend diese Adriamycinester Expired DE2627146C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26271/75A GB1499026A (en) 1975-06-20 1975-06-20 Adriamycin esters

Publications (3)

Publication Number Publication Date
DE2627146A1 DE2627146A1 (de) 1976-12-30
DE2627146B2 DE2627146B2 (de) 1978-06-29
DE2627146C3 true DE2627146C3 (de) 1979-03-01

Family

ID=10241028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE762627146A Expired DE2627146C3 (de) 1975-06-20 1976-06-16 Adriamycinester, Verfahren zu deren Herstellung und pharmazeutische Mittel enthaltend diese Adriamycinester

Country Status (15)

Country Link
US (1) US4031211A (enExample)
JP (1) JPS525756A (enExample)
AT (1) AT342772B (enExample)
AU (1) AU502848B2 (enExample)
BE (1) BE843120A (enExample)
CA (1) CA1047032A (enExample)
CH (1) CH623830A5 (enExample)
DE (1) DE2627146C3 (enExample)
DK (1) DK270876A (enExample)
FR (1) FR2314727A1 (enExample)
GB (1) GB1499026A (enExample)
NL (1) NL7606455A (enExample)
SE (1) SE7606971L (enExample)
SU (1) SU667143A3 (enExample)
ZA (1) ZA763548B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL170737C (nl) * 1975-11-12 1982-12-16 Rhone Poulenc Ind Werkwijze voor het bereiden van tegen tumoren werkzame esters van adriamycine, alsmede voor het bereiden van geneesmiddelen met anti-tumoractiviteit.
GB1511680A (en) * 1975-11-18 1978-05-24 Farmaceutici Italia Daunosaminyl anthracyclinones
GB1518390A (en) * 1976-03-30 1978-07-19 Farmaceutici Italia Doxorubicin thioesters
US4277466A (en) * 1978-08-29 1981-07-07 Institut International De Pathologie Cellulaire Et Moleculaire Complexes of DNA and esters derived from daunorubicine, their preparation and use
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
DE3500017A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-haloanthracyclinester
DE3500023A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-desoxyanthracyclinester
DE3500029A1 (de) * 1985-01-02 1986-09-04 Farmitalia Carlo Erba S.p.A., Mailand/Milano Anthracyclinester
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
GB2169285A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxydoxorubicin-14-esters
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
EP2061900A2 (en) 2006-08-25 2009-05-27 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives

Also Published As

Publication number Publication date
JPS5610918B2 (enExample) 1981-03-11
ZA763548B (en) 1977-07-27
FR2314727B1 (enExample) 1978-10-20
DK270876A (da) 1976-12-21
JPS525756A (en) 1977-01-17
AU502848B2 (en) 1979-08-09
SE7606971L (sv) 1976-12-21
DE2627146B2 (de) 1978-06-29
AT342772B (de) 1978-04-25
FR2314727A1 (fr) 1977-01-14
BE843120A (fr) 1976-10-18
CA1047032A (en) 1979-01-23
US4031211A (en) 1977-06-21
NL7606455A (nl) 1976-12-22
GB1499026A (en) 1978-01-25
SU667143A3 (ru) 1979-06-05
AU1500776A (en) 1977-12-22
CH623830A5 (enExample) 1981-06-30
DE2627146A1 (de) 1976-12-30
ATA440876A (de) 1977-08-15

Similar Documents

Publication Publication Date Title
DE2525633C3 (enExample)
DE2527914C3 (de) Vincaminderivate, Verfahren zu ihrer Herstellung und pharmazeutische Mittel
DE2627146B2 (de) Adriamycinester, Verfahren zu deren Herstellung und pharmazeutische Mittel enthaltend diese Adriamycinester
DE2141634B2 (de) Neue Isoindolinderivate, ihre Herstellung und Zusammensetzungen, die sie enthalten
DE19547958B4 (de) Anthracyclin-Derivate
DE2515629A1 (de) Paromomycin-derivate, verfahren zu ihrer herstellung und arzneimittel
DE2804099A1 (de) Carminomycinderivate, verfahren zu ihrer herstellung und ihre verwendung
DE1815808A1 (de) Benzolderivate
DE1911464B2 (de) 3,4-Dihydroisochinoline, Verfahren zu ihrer Herstellung und Arzneimittel
DE1595876A1 (de) Verfahren zur Herstellung von Aminomethylderivaten von Rifamycin SV
DE3028148A1 (de) N-glykosylderivate der antibiotika aus der anthracylingruppe, verfahren zu deren herstellung und arzneimittel
DE2632118A1 (de) Apovincaminolester und verfahren zu deren herstellung
DE2735455B2 (de) Daunomycinanaloga, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2403786A1 (de) Neue derivate der cumarine
DE2446640A1 (de) Neue gentamicinderivate, verfahren zur herstellung derselben und diese enthaltende antibiotisch wirksame zusammensetzungen
DE2713745A1 (de) Doxorubicinthioester und verfahren zu deren herstellung
DE69917440T2 (de) 5-Imino-13-desoxy-antracyclin-Derivate, ihre Verwendung sowie Verfahren zu deren Herstellung
DE2430510C3 (de) 16,17-Dihydroapovincaminsäureamide, Verfahren zu deren Herstellung und Arzneimittel, welche diese Verbingungen enthalten
DE2611162C2 (enExample)
DE2026040A1 (de) Imidazolnbosylcyclophosphate
CH637401A5 (de) Acylderivate der 2-(3-(2-chloraethyl)-3-nitrosoureido)-2-desoxy-d-glucopyranose.
DE1620124C3 (de) 8-Hydroxychinolinderivate
DE2241076B2 (de) Tetracyclinkomplex und dessen Salze, Verfahren zu dessen Herstellung und diesen Komplex enthaltende pharmazeutische Zusammensetzungen
DE936592C (de) Verfahren zur Herstellung eines blut- und harnzuckersenkenden Praeparates aus trioxyflavonglukosidhaltigen Pflanzenteilen
DE2031359C3 (de) 1,3,8-Triazaspiro eckige Klammer auf 4,5 eckige Klammer zu decan-2,4-dithione und Verfahren zu deren Herstellung

Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee