DE2556122C2 - Substituierte Benzoldisulfonamide, Verfahren zu deren Herstellung und diese enthaltende Mittel - Google Patents

Substituierte Benzoldisulfonamide, Verfahren zu deren Herstellung und diese enthaltende Mittel

Info

Publication number
DE2556122C2
DE2556122C2 DE2556122A DE2556122A DE2556122C2 DE 2556122 C2 DE2556122 C2 DE 2556122C2 DE 2556122 A DE2556122 A DE 2556122A DE 2556122 A DE2556122 A DE 2556122A DE 2556122 C2 DE2556122 C2 DE 2556122C2
Authority
DE
Germany
Prior art keywords
amino
compound
general formula
mixture
benzenedisulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2556122A
Other languages
German (de)
English (en)
Other versions
DE2556122A1 (de
Inventor
Helmut Hugo Matawan N.J. Mrozik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/616,331 external-priority patent/US4064239A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2556122A1 publication Critical patent/DE2556122A1/de
Application granted granted Critical
Publication of DE2556122C2 publication Critical patent/DE2556122C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/04—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2637—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions between a compound containing only oxygen and possibly halogen as hetero-atoms and a halogenated hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE2556122A 1974-12-16 1975-12-12 Substituierte Benzoldisulfonamide, Verfahren zu deren Herstellung und diese enthaltende Mittel Expired DE2556122C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53335274A 1974-12-16 1974-12-16
US05/616,331 US4064239A (en) 1974-12-16 1975-09-26 Halogenated unsaturated alkyl benzenedisulfonamides as anthelmintics

Publications (2)

Publication Number Publication Date
DE2556122A1 DE2556122A1 (de) 1976-06-24
DE2556122C2 true DE2556122C2 (de) 1986-05-22

Family

ID=27064157

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2556122A Expired DE2556122C2 (de) 1974-12-16 1975-12-12 Substituierte Benzoldisulfonamide, Verfahren zu deren Herstellung und diese enthaltende Mittel

Country Status (16)

Country Link
AR (1) AR218216A1 (cs)
CA (1) CA1058194A (cs)
DE (1) DE2556122C2 (cs)
DK (1) DK145756C (cs)
FI (1) FI64799C (cs)
FR (1) FR2294710A1 (cs)
GB (1) GB1485897A (cs)
IE (1) IE42203B1 (cs)
IL (1) IL48610A (cs)
LU (1) LU74019A1 (cs)
NL (2) NL187394C (cs)
NO (1) NO142667C (cs)
NZ (1) NZ179477A (cs)
OA (1) OA05183A (cs)
PH (1) PH12041A (cs)
SE (1) SE426817B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107868024A (zh) * 2017-10-25 2018-04-03 浙江海正药业股份有限公司 克洛索隆的晶型及其制备方法和用途
CN113773235B (zh) * 2021-08-20 2022-06-17 北大方正集团有限公司 一种氯舒隆的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1483222A (fr) * 1965-06-24 1967-06-02 Merck & Co Inc Production de nouveaux dérivés, substitués à l'azote, de la 5-chloro-2, 4-disulfamoylaniline
SE410598B (sv) * 1973-05-11 1979-10-22 Merck & Co Inc Forfarande for framstellning av bensendisulfonamider med anthelmintisk verkan

Also Published As

Publication number Publication date
IE42203B1 (en) 1980-06-18
NL7514163A (nl) 1976-06-18
FI64799C (fi) 1984-01-10
FI753392A7 (cs) 1976-06-17
NL187394C (nl) 1991-09-16
DK145756B (da) 1983-02-21
NL187394B (nl) 1991-04-16
FI64799B (fi) 1983-09-30
IL48610A0 (en) 1976-02-29
IE42203L (en) 1976-06-16
DE2556122A1 (de) 1976-06-24
DK145756C (da) 1983-08-08
FR2294710B1 (cs) 1979-09-21
SE7513569L (sv) 1976-06-17
GB1485897A (en) 1977-09-14
DK544775A (da) 1976-06-17
NZ179477A (en) 1978-04-03
AU8743575A (en) 1977-06-16
NO142667B (no) 1980-06-16
NO142667C (no) 1980-09-24
LU74019A1 (cs) 1976-11-11
IL48610A (en) 1979-10-31
OA05183A (fr) 1981-01-31
NL930115I1 (nl) 1993-10-18
NO754087L (cs) 1976-06-17
CA1058194A (en) 1979-07-10
FR2294710A1 (fr) 1976-07-16
SE426817B (sv) 1983-02-14
PH12041A (en) 1978-10-16
AR218216A1 (es) 1980-05-30

Similar Documents

Publication Publication Date Title
DD207714A5 (de) Verfahren zur herstellung von benzimidazolen
DE2041771B2 (de) derivate
DE2556122C2 (de) Substituierte Benzoldisulfonamide, Verfahren zu deren Herstellung und diese enthaltende Mittel
DE2129960C2 (de) Thioureidoderivate enthaltende therapeutische Zusammensetzungen, Verfahren zu deren Herstellung sowie die Thioureidoderivate
DE1667893A1 (de) Neue Anthelminthica
CH619688A5 (cs)
DE1545718A1 (de) Benzimidazole
DE2300447C2 (de) Substituierte 3-Cyanobenzolsulfonamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0177907B1 (de) Neue 2-Pyridin-thiol-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
EP0241834A2 (de) Verwendung von 3-Carbamoyl-4-hydroxy-cumarinen zur Bekämpfung von parasitären Helminthen, neue 3-Carbamoyl-4-hydroxy-cumarine und ihre Herstellung
DE2653181C2 (de) 4-Amino-1,3-benzoldisulfonamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Tierarzneimittel
DE1445752A1 (de) 2-Thio-tetrahydro-1,3,5-thiadiazine und Verfahren zu ihrer Herstellung
DE2204665A1 (de) Verbindungen mit anthelminthischer wirkung und ihre herstellung und mittel und verfahren zur bekaempfung von helminthen
DE2147857C2 (de) Substituierte 6-Phenyl-imidazo[2,1-b]-thiazole, Verfahren zu ihrer Herstellung und sie enthaltende anthelmintische Mittel
DE2143646A1 (de) 2-Amino-l,5-benzodiazocinderivate und Verfahren zu ihrer Herstellung
DE2325036C3 (de) Arylenverbindungen sowie diese enthaltende Wurmmittel
EP0007616B1 (de) Isothiocyanobenzthiazolderivat, Verfahren zu seiner Herstellung und seine Anwendung in anthelmintischen Mitteln
DE2848493A1 (de) Pharmazeutische zusammensetzung zum abtoeten von inneren parasiten bei warmbluetern, welche als wirkstoff ein dinitriertes diphenylmethanderivat enthalten
DE2218787A1 (de) Substituierte Benzolsulfonamide
DE1252204B (de) Verfahren zur Herstellung von 2,4-Dinitropyrrolderivaten
DE2422768A1 (de) Benzoldisulfonamide als wurmmittel
DE2243015A1 (de) 4-nitro-5-cyanimidazole und verfahren zur herstellung derselben
DE2541752A1 (de) Anthelminthisch wirksame 2-carbalkoxyamino-5(6)-phenyl-sulfonyloxy- benzimidazole und verfahren zu ihrer herstellung
EP0150719B1 (de) Substituierte Salicylsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2948885C2 (cs)

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: ABITZ, W., DIPL.-ING.DR.-ING. MORF, D., DR., PAT.-

D2 Grant after examination
8364 No opposition during term of opposition