DE2541342A1 - Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben - Google Patents

Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben

Info

Publication number
DE2541342A1
DE2541342A1 DE19752541342 DE2541342A DE2541342A1 DE 2541342 A1 DE2541342 A1 DE 2541342A1 DE 19752541342 DE19752541342 DE 19752541342 DE 2541342 A DE2541342 A DE 2541342A DE 2541342 A1 DE2541342 A1 DE 2541342A1
Authority
DE
Germany
Prior art keywords
phenoxy
acid
general formula
yield
aethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752541342
Other languages
German (de)
English (en)
Inventor
Wolfgang Prof Dr Med Schaumann
Kurt Dr Ing Stach
Karlheinz Dr Rer Nat Stegmeier
Ernst-Christian Dr Rer N Witte
Hans Peter Dr Rer Nat Wolff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19752541342 priority Critical patent/DE2541342A1/de
Priority to US05/719,878 priority patent/US4151303A/en
Priority to HU76BO1632A priority patent/HU175052B/hu
Priority to FI762614A priority patent/FI762614A7/fi
Priority to CA261,125A priority patent/CA1068292A/en
Priority to NZ182021A priority patent/NZ182021A/xx
Priority to DK412376A priority patent/DK412376A/da
Priority to PT65585A priority patent/PT65585B/pt
Priority to GB37766/76A priority patent/GB1499097A/en
Priority to SU762397802A priority patent/SU664561A3/ru
Priority to AR264689A priority patent/AR211552A1/es
Priority to CH1165076A priority patent/CH627152A5/de
Priority to BE170601A priority patent/BE846162A/xx
Priority to IT27196/76A priority patent/IT1078751B/it
Priority to NL7610182A priority patent/NL7610182A/xx
Priority to AT684676A priority patent/AT358012B/de
Priority to ZA765531A priority patent/ZA765531B/xx
Priority to DD194795A priority patent/DD126217A5/xx
Priority to LU75801A priority patent/LU75801A1/xx
Priority to SE7610214A priority patent/SE7610214L/xx
Priority to IE2053/76A priority patent/IE43627B1/en
Priority to AU17789/76A priority patent/AU497932B2/en
Priority to CS7600006005A priority patent/CS185645B2/cs
Priority to PL1976192444A priority patent/PL103550B1/pl
Priority to FR7627858A priority patent/FR2324295A1/fr
Priority to ES451627A priority patent/ES451627A1/es
Priority to JP51111695A priority patent/JPS5236637A/ja
Priority to IL50507A priority patent/IL50507A/xx
Publication of DE2541342A1 publication Critical patent/DE2541342A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19752541342 1975-09-17 1975-09-17 Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben Withdrawn DE2541342A1 (de)

Priority Applications (28)

Application Number Priority Date Filing Date Title
DE19752541342 DE2541342A1 (de) 1975-09-17 1975-09-17 Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben
US05/719,878 US4151303A (en) 1975-09-17 1976-09-01 Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions
HU76BO1632A HU175052B (hu) 1975-09-17 1976-09-10 Sposob poluchenija proizvodnykh 2-/4-/acilamino-alkil/-fenoksi/-alkilkarbonovo j kisloty
FI762614A FI762614A7 (https=) 1975-09-17 1976-09-10
CA261,125A CA1068292A (en) 1975-09-17 1976-09-10 Phenoxyalkylcarboxylic acid derivatives
NZ182021A NZ182021A (en) 1975-09-17 1976-09-13 Phenoxyalkylcarboxylic acid derivatives and pharmaceuticalcompositions
DK412376A DK412376A (da) 1975-09-17 1976-09-13 Phenoxyalkylcarbonsyrer og fremgangsmade til deres fremstilling
PT65585A PT65585B (de) 1975-09-17 1976-09-13 Neue phenoxyalkylcarbonsauren und verfahren zur herstellung derselben
GB37766/76A GB1499097A (en) 1975-09-17 1976-09-13 Phenoxyalkylcarboxylic acid derivatives
SU762397802A SU664561A3 (ru) 1975-09-17 1976-09-13 Способ получени производных 2-/4(ациламиноалкил)-фенокси/-алкилкарбоновой кислоты или их солей
AR264689A AR211552A1 (es) 1975-09-17 1976-09-13 Un procedimiento para preparar derivados del acido 2(4(acilamino-alquil)-fenoxi)alcanoico
CH1165076A CH627152A5 (https=) 1975-09-17 1976-09-14
BE170601A BE846162A (fr) 1975-09-17 1976-09-14 Nouveaux derives d'acides phenoxy-alkyl-carboxyliques et procede pour leur preparation
IT27196/76A IT1078751B (it) 1975-09-17 1976-09-14 Acidi fenossialchilcarbossilici e processo per la loro preparazione
NL7610182A NL7610182A (nl) 1975-09-17 1976-09-14 Werkwijze ter bereiding van nieuwe fenoxyalkyl- carbonzuurderivaten.
AT684676A AT358012B (de) 1975-09-17 1976-09-15 Verfahren zur herstellung von neuen phenoxy- alkancarbonsaeuren und deren alkylestern
ZA765531A ZA765531B (en) 1975-09-17 1976-09-15 New phenoxyalkylcarboxylic acid derivatives
DD194795A DD126217A5 (https=) 1975-09-17 1976-09-15
LU75801A LU75801A1 (https=) 1975-09-17 1976-09-15
SE7610214A SE7610214L (sv) 1975-09-17 1976-09-15 Nya fenoxialkylkarbonsyror
IE2053/76A IE43627B1 (en) 1975-09-17 1976-09-15 Phenoxyalkylcarboxylic acid derivatives
AU17789/76A AU497932B2 (en) 1975-09-17 1976-09-15 Phenoxyalkylcarboxylic acid derivatives
CS7600006005A CS185645B2 (en) 1975-09-17 1976-09-16 Method of producing new derivatives of phenoxyalkylcarboxylic acids
PL1976192444A PL103550B1 (pl) 1975-09-17 1976-09-16 Sposob wytwarzania nowych kwasow fenoksyalkilokarboksylowych
FR7627858A FR2324295A1 (fr) 1975-09-17 1976-09-16 Nouveaux acides phenoxyalcoylcarboxyliques et procede permettant leur production
ES451627A ES451627A1 (es) 1975-09-17 1976-09-17 Procedimiento para la preparacion de derivados de acidos fe-noxialcohilcarboxilicos.
JP51111695A JPS5236637A (en) 1975-09-17 1976-09-17 Phenoxy alkyl carboxylic acid derivatives *process for preparing the same and pharmaceutical containing the same having lipidddepleting activity
IL50507A IL50507A (en) 1975-09-17 1976-09-17 Substituted aryl(or aryloxy)alkyl(or alkoxy)carbonylaminophenoxy-alkylcarboxylic acid derivatives,their preparation and pharmaceutical compositions containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752541342 DE2541342A1 (de) 1975-09-17 1975-09-17 Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
DE2541342A1 true DE2541342A1 (de) 1977-03-31

Family

ID=5956639

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752541342 Withdrawn DE2541342A1 (de) 1975-09-17 1975-09-17 Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben

Country Status (28)

Country Link
US (1) US4151303A (https=)
JP (1) JPS5236637A (https=)
AR (1) AR211552A1 (https=)
AT (1) AT358012B (https=)
AU (1) AU497932B2 (https=)
BE (1) BE846162A (https=)
CA (1) CA1068292A (https=)
CH (1) CH627152A5 (https=)
CS (1) CS185645B2 (https=)
DD (1) DD126217A5 (https=)
DE (1) DE2541342A1 (https=)
DK (1) DK412376A (https=)
ES (1) ES451627A1 (https=)
FI (1) FI762614A7 (https=)
FR (1) FR2324295A1 (https=)
GB (1) GB1499097A (https=)
HU (1) HU175052B (https=)
IE (1) IE43627B1 (https=)
IL (1) IL50507A (https=)
IT (1) IT1078751B (https=)
LU (1) LU75801A1 (https=)
NL (1) NL7610182A (https=)
NZ (1) NZ182021A (https=)
PL (1) PL103550B1 (https=)
PT (1) PT65585B (https=)
SE (1) SE7610214L (https=)
SU (1) SU664561A3 (https=)
ZA (1) ZA765531B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004011A1 (de) * 1978-03-04 1979-09-19 Roche Diagnostics GmbH Phenoxyalkylcarbonsäure-Derivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
WO1995005358A1 (de) * 1993-08-14 1995-02-23 Boehringer Mannheim Gmbh Verwendung von phenolen und phenolderivaten als arzneimittel mit fibrinogensenkender wirkung
EP0974573A4 (en) * 1997-03-03 2001-01-31 Yakult Honsha Kk PHENYL PROPENONE COMPOUNDS AND DRUGS CONTAINING THEM
FR2875805A1 (fr) * 2004-09-27 2006-03-31 Genfit S A Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639935A1 (de) * 1976-09-04 1978-03-09 Hoechst Ag Benzoesaeuren und verfahren zu ihrer herstellung
JPS5649906B2 (en) * 1978-05-12 1981-11-25 Boehringer Mannheim Gmbh Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxy**isoethylacetic acid
JPS56145261A (en) * 1980-04-10 1981-11-11 Kaken Pharmaceut Co Ltd Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredient
KR970006473B1 (ko) * 1987-06-08 1997-04-28 오노 화아마슈티칼 캄파니 리미팃드 신나모일아미드 유도체, 그들의 제조방법, 그들을 함유하는 제약학적 조성물 및 그들의 사용
US5248785A (en) * 1990-02-12 1993-09-28 Virginia Commonwealth University Using allosteric hemoglobin modifiers to decrease oxygen affinity in blood
US5705521A (en) * 1990-02-12 1998-01-06 The Center For Innovative Technology Use of allosteric hemoglobin modifiers in combination with radiation therapy to treat carcinogenic tumors
US5122539A (en) * 1990-02-12 1992-06-16 Center For Innovative Technology Allosteric hemoglobin modifiers useful for decreasing oxygen affinity and preserving oxygen carrying capability of stored blood
US5872282A (en) * 1990-12-07 1999-02-16 Virginia Commonwealth University Allosteric modifiers of hemoglobin
WO2002046176A1 (en) * 2000-12-05 2002-06-13 Nippon Chemiphar Co., Ltd. Ppar (peroxisome proliferator activated receptor) activators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6717061A (https=) * 1966-12-21 1968-06-24
DE2230383C3 (de) * 1971-10-01 1981-12-03 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben
AT341512B (de) * 1975-01-09 1978-02-10 Thomae Gmbh Dr K Verfahren zur herstellung von neuen biphenylathern

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004011A1 (de) * 1978-03-04 1979-09-19 Roche Diagnostics GmbH Phenoxyalkylcarbonsäure-Derivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
WO1995005358A1 (de) * 1993-08-14 1995-02-23 Boehringer Mannheim Gmbh Verwendung von phenolen und phenolderivaten als arzneimittel mit fibrinogensenkender wirkung
EP0974573A4 (en) * 1997-03-03 2001-01-31 Yakult Honsha Kk PHENYL PROPENONE COMPOUNDS AND DRUGS CONTAINING THEM
FR2875805A1 (fr) * 2004-09-27 2006-03-31 Genfit S A Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations
WO2006035157A3 (fr) * 2004-09-27 2006-06-29 Genfit Composes derives de n- (benzyl) phenylacetamide substitues , preparation et utilisations comme ligands des ppar dans le traitement des dereglements lipidiques et/ou glucidiques

Also Published As

Publication number Publication date
PT65585B (de) 1978-03-28
IT1078751B (it) 1985-05-08
CH627152A5 (https=) 1981-12-31
AT358012B (de) 1980-08-11
DK412376A (da) 1977-03-18
NZ182021A (en) 1978-06-02
IL50507A (en) 1979-11-30
AU1778976A (en) 1978-03-23
SE7610214L (sv) 1977-03-18
IE43627L (en) 1977-03-17
ES451627A1 (es) 1977-08-01
FI762614A7 (https=) 1977-03-18
PL103550B1 (pl) 1979-06-30
ATA684676A (de) 1980-01-15
IL50507A0 (en) 1976-11-30
NL7610182A (nl) 1977-03-21
BE846162A (fr) 1977-03-14
AR211552A1 (es) 1978-01-30
HU175052B (hu) 1980-05-28
IE43627B1 (en) 1981-04-22
SU664561A3 (ru) 1979-05-25
FR2324295A1 (fr) 1977-04-15
PT65585A (de) 1976-10-01
LU75801A1 (https=) 1977-05-06
AU497932B2 (en) 1979-01-25
CS185645B2 (en) 1978-10-31
US4151303A (en) 1979-04-24
DD126217A5 (https=) 1977-06-29
FR2324295B1 (https=) 1978-11-17
CA1068292A (en) 1979-12-18
GB1499097A (en) 1978-01-25
JPS5236637A (en) 1977-03-22
ZA765531B (en) 1977-09-28

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination